Chapter 187 - colloid osmotic pressure and osmolality monitoring Flashcards
goal COP to reduce the risk of oedema formation in dogs and cats?
15 mm Hg
which term is redundant?
colloid osmotic pressure
colloid oncotic pressure
oncotic pressure
colloid oncotic pressure
what is the percentage contribution of albumin (and associated cations) to COP?
60-70%
what is the percentage contribution of globulins to COP?
30-40%
state Starling’s principal
net rate of capillary filtration = the difference between capillary and interstitial hydrostatic pressure minus the osmotic reflection coefficient outside the difference between the plasma and interstitial oncotic pressure
which variable(s) in Starling’s principal can be manipulated clinically?
plasma oncotic pressure
capillary hydrostatic pressure
in the revised Starling’s principal, which variable is changed?
COP of the subglycocalyx space is used instead of the COP of the interstitium
to what level will the total solids (by refractometer) trend towards in patients receiving artificial colloids?
4-4.2mg/dL
published normal COP for canine and feline plasma?
dogs: 21-25mmHg
cats: 23-25mmHg
published normal COP for canine and feline whole blood?
dogs: 17.85-22.05mmHg
cats: 21-28.4mmHg
indications for COP measurement
- patients receiving artificial colloids
- patients with oedema
- patients treated with aggressive crystalloid therapy with with low serum albumin
3 strategies for treatment of low COP?
plasma
human/canine albumin solutions
artificial colloids
osmolarity v osmolality
osmolality: number of osmotically active particles/kg of solution
osmolarity: number of particles/L volume of solution
normal osmolality?
dogs: 290-310mOsm/kg
cats: 290-330mOsm/kg
formula for calculation of osmolality
2(Na+) + (BUN/2.8) + (glucose/18)