Chapter 172- Chancroid Flashcards
Acute ulcerative disease localized at the anogenital area and associated with inguinal adenitis or bubo
Chancroid
Chancroid manifests as painful soft ulcers with ragged undermined margins that develops ___ weeks after inoculation
1-2
Diagnostic test for chancroid
Nucleic acid amplification test
Reservoid in all reported outbreaks of chancroid
Low class prostitutes
Reduces risk of chancroid transmission
Male circumcision
Chancroid ulcer is an important risk factor for
Heterosexual spread of HIV
Duration of infectivity is estimated to be ___ for women
45 days
Transmission rate from males to females is __% and females to males is __%
70%/sexual act
?
Incubation period of chancroid
3-7 days
Vesicles are commonly seen in chancroid.
True or False
False, not seen
Chancroid ulcers in males are found in (3)
Prepuce
Frenulum
Glans
Meatus and shaft of penis and anus are involved more commonly in chancroid.
True or False
Less commonly
Chancroid ulcers in females are found in (4)
Fourchette
Labia minora
Vestibule
Painful inguinal adenitis (bubo) occurs in __% of patients within a few days to 2 weeks
50
Buboes are bilateral and may rupture spontaneously.
True or False
False, unilateral
In industrialized countries, isolated painful chancres are most likely caused by ___
Herpes simplex virus
In a high percentage of ulcers, no pathogen can be isolated but coninfections with syphilis or herpes simplex are not uncommon
Ulcus mixtum
Lesion that becomes confluent, spreading by extension and autoinoculation in the groin or thigh
Large serpiginous ulcer (ulcus molle serpiginosum)
Rapid and profound destruction of tissue caused by superinfection with fusospirochetess
Phagedenic chancroid
Ulcus molle gangrenosum
Small ulcer that resolves spontaneously in a few days ff by regional lymphadenopathy in 2-3 weeks
Transient chancroid (Chancre mou volant)
Multiple small ulcers in follicular distribution
Follicular chancroid
Single lesion extends peripherally and shows extensive ulceration
Giant chancroid
Granulomatous ulcerated papule that resemble dinivanosis or condyloma
Papular chancroid
Ulcus molle elevatum
3 classic etiologic agents for ulceration
H. Ducreyi
T. Pallidum
Herpes simplex
Low sensitivity and specificity hence not recommended for diagnosis
Chancroid
Most frequent complaint of chancroid
Local pain
Reinfections are impossible.
True or False
False, possible hence use condoms properly
WHO/CDC recommendation for chancroid (4)
Azithromycin 1g PO in single dose
Ceftriaxone 250mg IM in single dose
Ciprofloxacin 500mg PO BID for 3 days
Erythromycin 500mg PO QID for 7 days
In pregnancy, treatment of choice is
Ceftriaxone 250mg IM in a single dose
Risk factor for reinfection and Tx failure for chancroid (2)
HIV infection
Lack of circumcision
If patient complains of one or more small blisters with history of recent blisters, treat for
Herpes
If patient complains of isolated small ulcer and painful matted gland, treat for
LGV
Chancroid
Syphiliis
If patient complains of ulcer, treat for
Syphilis
Chancroid
Sexual contact of patients within __ days should be examined and treated regardless of whether symptoms of disease are present
10 days
H. Ducreyi is considered as a cause of chronic limb ulcers in adults and in children. True or False
True
Treatment for suppurative nodes
Punctured with a large syringe, emtered laterally, to prevent spontaneous rupture and sinus tract formation
Not incised
