Chapter 172- Chancroid Flashcards

1
Q

Acute ulcerative disease localized at the anogenital area and associated with inguinal adenitis or bubo

A

Chancroid

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2
Q

Chancroid manifests as painful soft ulcers with ragged undermined margins that develops ___ weeks after inoculation

A

1-2

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3
Q

Diagnostic test for chancroid

A

Nucleic acid amplification test

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4
Q

Reservoid in all reported outbreaks of chancroid

A

Low class prostitutes

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5
Q

Reduces risk of chancroid transmission

A

Male circumcision

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6
Q

Chancroid ulcer is an important risk factor for

A

Heterosexual spread of HIV

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7
Q

Duration of infectivity is estimated to be ___ for women

A

45 days

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8
Q

Transmission rate from males to females is __% and females to males is __%

A

70%/sexual act

?

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9
Q

Incubation period of chancroid

A

3-7 days

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10
Q

Vesicles are commonly seen in chancroid.

True or False

A

False, not seen

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11
Q

Chancroid ulcers in males are found in (3)

A

Prepuce
Frenulum
Glans

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12
Q

Meatus and shaft of penis and anus are involved more commonly in chancroid.
True or False

A

Less commonly

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13
Q

Chancroid ulcers in females are found in (4)

A

Fourchette
Labia minora
Vestibule

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14
Q

Painful inguinal adenitis (bubo) occurs in __% of patients within a few days to 2 weeks

A

50

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15
Q

Buboes are bilateral and may rupture spontaneously.

True or False

A

False, unilateral

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16
Q

In industrialized countries, isolated painful chancres are most likely caused by ___

A

Herpes simplex virus

17
Q

In a high percentage of ulcers, no pathogen can be isolated but coninfections with syphilis or herpes simplex are not uncommon

A

Ulcus mixtum

18
Q

Lesion that becomes confluent, spreading by extension and autoinoculation in the groin or thigh

A

Large serpiginous ulcer (ulcus molle serpiginosum)

19
Q

Rapid and profound destruction of tissue caused by superinfection with fusospirochetess

A

Phagedenic chancroid

Ulcus molle gangrenosum

20
Q

Small ulcer that resolves spontaneously in a few days ff by regional lymphadenopathy in 2-3 weeks

A
Transient chancroid
(Chancre mou volant)
21
Q

Multiple small ulcers in follicular distribution

A

Follicular chancroid

22
Q

Single lesion extends peripherally and shows extensive ulceration

A

Giant chancroid

23
Q

Granulomatous ulcerated papule that resemble dinivanosis or condyloma

A

Papular chancroid

Ulcus molle elevatum

24
Q

3 classic etiologic agents for ulceration

A

H. Ducreyi
T. Pallidum
Herpes simplex

25
Q

Low sensitivity and specificity hence not recommended for diagnosis

A

Chancroid

26
Q

Most frequent complaint of chancroid

A

Local pain

27
Q

Reinfections are impossible.

True or False

A

False, possible hence use condoms properly

28
Q

WHO/CDC recommendation for chancroid (4)

A

Azithromycin 1g PO in single dose
Ceftriaxone 250mg IM in single dose
Ciprofloxacin 500mg PO BID for 3 days
Erythromycin 500mg PO QID for 7 days

29
Q

In pregnancy, treatment of choice is

A

Ceftriaxone 250mg IM in a single dose

30
Q

Risk factor for reinfection and Tx failure for chancroid (2)

A

HIV infection

Lack of circumcision

31
Q

If patient complains of one or more small blisters with history of recent blisters, treat for

A

Herpes

32
Q

If patient complains of isolated small ulcer and painful matted gland, treat for

A

LGV
Chancroid
Syphiliis

33
Q

If patient complains of ulcer, treat for

A

Syphilis

Chancroid

34
Q

Sexual contact of patients within __ days should be examined and treated regardless of whether symptoms of disease are present

A

10 days

35
Q

H. Ducreyi is considered as a cause of chronic limb ulcers in adults and in children. True or False

A

True

36
Q

Treatment for suppurative nodes

A

Punctured with a large syringe, emtered laterally, to prevent spontaneous rupture and sinus tract formation
Not incised