Chapter 156- Miscellaneous Bacterial Infections With Cutaneous Manifestations Flashcards
Presents as an exquisitely painful nodule on distal phalanx of finger that may progress to tenosynovitis or joint destruction
Seal finger
Pathogen of seal finger
Mycoplasma
Treatment of choice for seal finger
Tetracyclines for 4-6 weeks
Most coomin in pregnant women, neonates, patients with AIDS, in foodborne outbreaks
Human listeriosis
Listeria monocytogenes is ___ when cultured on blood sheep agar and ___ in broth
Beta hemolytic
Tumbling motility
Treatment for neonates with listeriosis
IV penicillin
In neonatal listeriosis with septicimeia or with meningitis, mortaity is approximately ___%
50
How to prevent listeriosis
Avoid unpasteurized dairy products, unwashed vegetables, and poorly cooked meats
Facultative anaerobic, pleomorphic, Gram (-) rods found in marine waters, estuaries, brackish lakes when water is above 20 C
Vibrio
Vibrio vulnificus can cause (3) clinical syndromes
Gastroenteritis
Primary sepsis
Primary wound infection
There is nearly always a history of contact with ___ or consumption or handling of ___ with Vibrio infection
Saltwater
Shellfish
Vibrio sp. that ferments lactose on MacConkey agar
V.vulnificus
Wound infections sustained in fresh water suggest infection with ___ than Vibrio
Aeromonas
Antibiotics of choice for Vibrio are
Doxycycline
Ceftazidime
Modified Dakin (0.025% NaOCl)
Patients with (3) should not eat raw shellfish
Cirrhosis
DM
AIDS
Disease with Aeromonas Hydrophila are also associated with
Medical use of leeches
MC presentation of Aeromonas hydrophila infection
Cellulitis associated with laceration followed by abscess formation
Treatment of Aeromonas hydrophila
Third gen cephalosporins
Fluoroquinolones
Aminoglycoside
Meloidosis caused by
Burkholderia pseudomallei
Susceptible to Burkholderia pseudomallei
Rice farmers with
DM
Chronic renal failure
Common presentation of meloidosis in children
Acute unilateral suppurative parotitis
Treatment for meloidosis
2 weeks of IV antibiotics
(Ceftazidime + Carbepenem)
Ff by TMP-SMX, Co-Amxiclav
Associated with percutaneous trauma while handling raw fish or poultry
Erysipeloid (Erysipelothrix rhusiopathiae)
Volaceous, warm, tender plaque with well defined margins involving the web spaces but spares the terminal phalange and does not progress beyond the wrist
Erysipeloid of Rosenbach
Treatment for erysipeloid
High dose penicillin or ampicillin for 7-10 days
Complication of erysipeloid
Subacute bacterial endocarditis of aortic valve
Most important reservoir of leptospirosis
Leptospira interrogans
2 clinical forms of leptospirosis
Mild, anicteric form
Severe icteric form (Weil disease)
Prominent jaundice, hepatomegaly, interstitial nephritis
Weil disease
Distinctive rash that appears on 4th- 5th day of illness with tender erythematous papules on the shins
Pretibial or Fort Bragg fever
Pretibial or Fort Bragg fever is caused by
L. Interrogans serovar autumnalis
Treatment for leptospirosis
Doxycycline
Penicillin
Untreated Weil disease have mortality rate of ___% due to renal failure
5 to 40%
Prophylaxis for leptospirosis
Doxycycline 200mg once weekly
Adherent asymmetrical gray leathery membranous pharyngeal lesions along tonsils and soft palate which may cause lethal airway obstruction
Diphtheria
Diphtheria exotoxin may cause (2)
Latent peripheral neuritis (2 weeks to several months) Lethal cardiomyopathy (1-2 weeks)
Tender pustules that break down into punched out ulcers covered by gray membranes
Cutaneous diphtheria
Culture for diphtheria
Loffler/Tellurite agar
Treatment for diphtheria
High dose IV penicillin
Diphtheria antitoxin IV
Tetanus and diphtheria toxoid should be given evvery ___ years
10
Resembles diphtheria but is caused by drinking raw milk
Corynebacterium ulcerans
Resembles diphtheria and can cause SSTIs after exposure to horse manure or cause pulmonary disease in AIDS patients
Rhodococcus equi
Colonizes or infects freshwater tilapia
Streptococcus iniae
In dolphins, S. Iniae causes slow growing nodular abscesses of skin, subQ giving it name of
Golf ball disease
Key element in Streptococcus iniae infection
Rapid onset of hand cellulitis in 1-3 days with ascending lymphangitis and fever
Treatment for Streptococcus iniae
Penicillin for 10 days
Gram (-) motile flagellated bacillus rarely pathogenic except to people with disorders of neutrophil function
Chromobacterium violaceum
Treatment consists of
Oral doxycycline + TMP-SMX
Difference od erysipeloid with erysipelase
In erysipeloid, there is central clearing