Chapter 17: Analgesics Flashcards by Sonya Narla | Brainscape

Q

Morphine

A

Natural or semisynthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Codeine

A

Natural or semisynthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Oxycodone

A

Natural or semisynthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Hydrocodone

A

Natural or semisynthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Tramadol

A

Natural or semisynthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Methadone

A

Synthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Fentanyl

A

Synthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Alfentanil

A

Synthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Sufentanil

A

Synthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Ramifentanil

A

Synthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Meperidine

A

Synthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

midriasis - pupils big and wide

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Levorphanol

A

Synthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Propoxyphene

A

Synthetic agonists of the μ-opioid receptor that result in inhibition of neurotransmission

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Butorphanol

A

Partial μ-receptor agonist

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Buprenorphine

A

Partial μ-receptor agonist

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Nalbuphine

A

κ-agonist with partial μ-antagonist activity

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Naloxone

A

Antagonists of μ-opioid receptor, thereby blocking endogenous or exogenous opioid effects

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Naltrexone

A

Antagonists of μ-opioid receptor, thereby blocking endogenous or exogenous opioid effects

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Alvimopan

A

Antagonists of μ-opioid receptor, thereby blocking endogenous or exogenous opioid effects

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Methylnaltrexone

A

Antagonists of μ-opioid receptor, thereby blocking endogenous or exogenous opioid effects

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Acetaminophen

A

NSAID - Affect prostaglandin synthetic pathway

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Aspirin

A

NSAID - Affect prostaglandin synthetic pathway

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Naproxen

A

NSAID - Affect prostaglandin synthetic pathway

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Ibuprofen

A

NSAID - Affect prostaglandin synthetic pathway

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Indomethacin

A

NSAID - Affect prostaglandin synthetic pathway

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Diclofenac

A

NSAID - Affect prostaglandin synthetic pathway

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Piroxicam

A

NSAID - Affect prostaglandin synthetic pathway

Q

Celecoxib

A

NSAID - Affect prostaglandin synthetic pathway

Q

Diclofenac

A

NSAID - Affect prostaglandin synthetic pathway

Q

Keterolac

A

NSAID - Affect prostaglandin synthetic pathway

Q

Amitirptyline

A

Tricyclic Antodepressant - Promote serotonergic and nonadrenergic neurotransmission by inhibiting neurotransmitter reuptake

Q

Nortriptyline

A

Tricyclic Antodepressant - Promote serotonergic and nonadrenergic neurotransmission by inhibiting neurotransmitter reuptake

Q

Imipramine

A

Tricyclic Antodepressant - Promote serotonergic and nonadrenergic neurotransmission by inhibiting neurotransmitter reuptake

Q

Desipramine

A

Tricyclic Antodepressant - Promote serotonergic and nonadrenergic neurotransmission by inhibiting neurotransmitter reuptake

Q

Duloxetine

A

Tricyclic Antodepressant - Promote serotonergic and nonadrenergic neurotransmission by inhibiting neurotransmitter reuptake

Q

Venlafaxine

A

Tricyclic Antodepressant - Promote serotonergic and nonadrenergic neurotransmission by inhibiting neurotransmitter reuptake

Q

Carbamazepine

A

Antiepileptic Drug or Antiarrythmic - Inhibit action potantial initiation or conduction

Q

Oxcarbazepine

A

Antiepileptic Drug or Antiarrythmic - Inhibit action potantial initiation or conduction

Q

Gabapentin

A

Antiepileptic Drug or Antiarrythmic - Inhibit action potantial initiation or conduction

Q

Pregabalin

A

Antiepileptic Drug or Antiarrythmic - Inhibit action potantial initiation or conduction

Q

Lamotrigine

A

Antiepileptic Drug or Antiarrythmic - Inhibit action potantial initiation or conduction

Q

Mexiletine

A

Antiepileptic Drug or Antiarrythmic - Inhibit action potantial initiation or conduction

Q

Ketamine

A

Blocks NMDA receptor-dependent postsynaptic depolariztion

Q

Dextromethorphan

A

Blocks NMDA receptor-dependent postsynaptic depolariztion

Q

Sumatriptan

A

5-HT10 Seretonin Receptor Agonist - Induce cerebrovascular vasoconstriction, reduce nociceptive transmission

Q

Rizatriptan

A

5-HT10 Seretonin Receptor Agonist - Induce cerebrovascular vasoconstriction, reduce nociceptive transmission

Q

Naratriptan

A

5-HT10 Seretonin Receptor Agonist - Induce cerebrovascular vasoconstriction, reduce nociceptive transmission

Q

Zolmitriptan

A

5-HT10 Seretonin Receptor Agonist - Induce cerebrovascular vasoconstriction, reduce nociceptive transmission

Q

Almotriptan

A

5-HT10 Seretonin Receptor Agonist - Induce cerebrovascular vasoconstriction, reduce nociceptive transmission

Q

Eletriptan

A

5-HT10 Seretonin Receptor Agonist - Induce cerebrovascular vasoconstriction, reduce nociceptive transmission

Q

Which drugs prevent morphine induced constipation, but have no effect on morphine analgesia?

A

Alvimopan and Methylnaltrexone

Q

Which drugs do you have to avoid if there is use of a MOAI, in order to avoid seretonin syndrome?

A

Dextromethorphan and Meperidine

Q

Which drugs active metabolite, M6G, is excreted in the kidney?

A

Morphine

Q

Which of these drugs is the most potent: Fentanyl, Alfentanil, Sufentanil?

A

Sufentanil

Q

Which of these drugs is the least potent: Fentanyl, Alfentanil, Sufentanil?

A

Alfentanil

Q

Due to its long duration of action, which drug is used to achieve long lasting pain relief in cancer patients?

A

Methadone

Q

Which opioid causes mydriasis rather than miosis?

A

Meperidine

Q

Which pain control drug may precipitate withdrawl in patients who have received opioids chronically?

A

Nalbuphine

Q

Which u-opioid receptor agonist has minimal abuse potential?

A

Tramadol

Q

Which drug has an unusually rapid metabolism and elimination rate?

A

Ramifentanil

Q

Which drug cannot be given via an epidural or intrathecally, because the glycine in the formulation may cause neurotoxicity?

A

Ramifentanil

Q

Which drugs produce morphine-like analgesia with milder euphoric effects?

A

Butorphanol and Buprenorphine

Q

Which drug’s usage is limited due to it’s psychomimetic effects?

A

Ketamine

Q

Which drug is used for anesthesia, that has minimal risk of respiratory depression?

A

Ketamine

Q

Which drug is used to treat neuropathic pain as well as the cough?

A

Dextromethorphan

Q

Which drug can be used to treat opioid and alcohol addiction?

A

Naltrexone

Q

Which drug can only be used to treat acute oipoid toxicity?

A

Naloxone