Chapter 17 Flashcards

1
Q

acetycholine (ACH)

A

excitatory neurotransmitter in the basal ganglia

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2
Q

basal ganglia

A

group of cell bodies located within the cerebrum involved in regulation of skeletal muscle tone and body movement

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3
Q

bradykinesia

A

slowed body movements

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4
Q

COMT

A

catechol-o-methyltransferase, the enzyme that metabolizes dopamine both peripherally and in the brain

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5
Q

DOPA decarvoxylase

A

dihydroxyphenylamine decarbonxylase, the enzyme that metabolizes the peripheral conversion of levodopa to dopamine

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6
Q

dopamine

A

inhibitory neurotransmitter in the basal ganglia

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7
Q

dyskinesia

A

abnormal involuntary body movements

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8
Q

dystonia

A

muscle spasms, facial grimacing and other involuntary movements and postures

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9
Q

MAO-B

A

monomaine oxidase0B the enzyme that selectively metabolizes dopamantine the brain

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10
Q

on-off phenomenon

A

alternating periods of movement mobility and immobility

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11
Q

parkinsonism

A

symptoms of Parkinson’s disease which include resting tremor muscle rigidity and disturbances of movement and postural balance

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12
Q

Parkinson’s disease

A

movement disorder of the basal ganglia caused by a deficiency of dopamine

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13
Q

postural instability

A

inability to maintain upright erect posture

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14
Q

muscle rigidity

A

a stiffness and inflexibility of movement

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15
Q

tremor

A

a trembling and involuntary rhythmic movement

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