Chapter 17

Question 1

acetycholine (ACH)

Answer 1

excitatory neurotransmitter in the basal ganglia

Question 2

basal ganglia

Answer 2

group of cell bodies located within the cerebrum involved in regulation of skeletal muscle tone and body movement

Question 3

bradykinesia

Answer 3

slowed body movements

Question 4

COMT

Answer 4

catechol-o-methyltransferase, the enzyme that metabolizes dopamine both peripherally and in the brain

Question 5

DOPA decarvoxylase

Answer 5

dihydroxyphenylamine decarbonxylase, the enzyme that metabolizes the peripheral conversion of levodopa to dopamine

Question 6

dopamine

Answer 6

inhibitory neurotransmitter in the basal ganglia

Question 7

dyskinesia

Answer 7

abnormal involuntary body movements

Question 8

dystonia

Answer 8

muscle spasms, facial grimacing and other involuntary movements and postures

Question 9

MAO-B

Answer 9

monomaine oxidase0B the enzyme that selectively metabolizes dopamantine the brain

Question 10

on-off phenomenon

Answer 10

alternating periods of movement mobility and immobility

Question 11

parkinsonism

Answer 11

symptoms of Parkinson’s disease which include resting tremor muscle rigidity and disturbances of movement and postural balance

Question 12

Parkinson’s disease

Answer 12

movement disorder of the basal ganglia caused by a deficiency of dopamine

Question 13

postural instability

Answer 13

inability to maintain upright erect posture

Question 14

muscle rigidity

Answer 14

a stiffness and inflexibility of movement

Question 15

tremor

Answer 15

a trembling and involuntary rhythmic movement