Chapter 17 Flashcards
acetycholine (ACH)
excitatory neurotransmitter in the basal ganglia
basal ganglia
group of cell bodies located within the cerebrum involved in regulation of skeletal muscle tone and body movement
bradykinesia
slowed body movements
COMT
catechol-o-methyltransferase, the enzyme that metabolizes dopamine both peripherally and in the brain
DOPA decarvoxylase
dihydroxyphenylamine decarbonxylase, the enzyme that metabolizes the peripheral conversion of levodopa to dopamine
dopamine
inhibitory neurotransmitter in the basal ganglia
dyskinesia
abnormal involuntary body movements
dystonia
muscle spasms, facial grimacing and other involuntary movements and postures
MAO-B
monomaine oxidase0B the enzyme that selectively metabolizes dopamantine the brain
on-off phenomenon
alternating periods of movement mobility and immobility
parkinsonism
symptoms of Parkinson’s disease which include resting tremor muscle rigidity and disturbances of movement and postural balance
Parkinson’s disease
movement disorder of the basal ganglia caused by a deficiency of dopamine
postural instability
inability to maintain upright erect posture
muscle rigidity
a stiffness and inflexibility of movement
tremor
a trembling and involuntary rhythmic movement