Chapter 17 Flashcards

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1
Q

Virulence

A

The ability of organism to overcome host defenses

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2
Q

First line defense against the invasion of pathogens

A

Mechanical and chemical barriers, such as skin
Mucous membranes
Body secretions
Certain reflexes

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3
Q

Two components of second defense

A

Phagocytes WBC

Natural killer cells

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4
Q

Three ways fever boosts the immune system

A

Stimulates phagocytes (wbc)
Increases metabolism
Decreases certain disease organism

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5
Q

Adaptive immunity

A

an individual who can overcome a disease or it’s harmful products.

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6
Q

Antigen

A

Any substance that induces an immune response.

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7
Q

Four types of t-cells

A

Cytotoxic (destroys directly)
Helper (releases interleukins to help the immune system)
Regulatory (Suppresses)
Memory (remember an antigen)

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8
Q

APC Role

A

Antigen presenting cells mobilizes the immune system against a particular foreign antigen.

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9
Q

Antibody

A

Substance produced in response to antigen. (Immunoglobulin.)

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10
Q

Cells that produce antibodies

A

B cell (lymphocytes)

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11
Q

Active form of adaptive immunity

A

Develops naturally through contact with a specific disease.

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12
Q

Natural passive

A

Is passed from another source. Mom to fetus.

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13
Q

Natural adoptive immunity

A

When the body produces antibodies in response to pathogen.

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14
Q

Artificial immunity

A

Involves an outside source to obtain antibodies

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15
Q

Vaccine

A

A prepared substance that initiates the immune response to a specific pathogen.

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16
Q

Booster

A

Is an artificial immunity to help maintain a high titer of antibodies in the blood.

17
Q

Antiserum

A

Ready to made serum that gives short-lived but effective protection against the organism.

18
Q

Anti sera

A

Used for animals, particularly horses which produces a large amount of antibodies.

19
Q

4 types of immune disorders

A

Allergy
Autoimmunity
Immune deficiency disease
Multiple myeloma

20
Q

Second line of defense

A

Initiated cells and chemicals in the body.

21
Q

Phagocytosis

A

WBC are taken in and destroys wastes and foreign materials.

22
Q

Neutrophils

A

Granular wbc

23
Q

Macrophages

A

Large wbc known as the big eater

24
Q

Cytokines and other chemicals

A

Interferons- interfere

Compliments- a group of proteins that help antibody, destroys foreign cells.

25
Q

Natural killer cells

A

A type of lymphocytes that destroys abnormal cells.

26
Q

Adoptive Immunity characteristics

A

Specific: responding to a specific pathogen.

Acquired- a specific particular disease and develops in a person’s lifetime

27
Q

Antigen

A

Most are proteins

Substance that cause immune response

28
Q

T-cells characteristic

A

Mature in thymus
Provide cell-mediated immunity
Originates (bone marrow)

29
Q

Example of Antigen

A

Dendritic cells
Macrophages
Some lymphocytes

30
Q

B cells characteristics

A

Mature in red bone marrow
Produced antibodies
Provide humoral immunity

31
Q

B cell types

A

Plasma cells-secrete antibodies

Memory B cells

32
Q

Functions of B cells

A
Bind together 
Prevent attachment
Promote phagocytes 
Active NK cells 
Neutralized toxins 
Active complement
33
Q

Allergy

A
Anaphylaxis(swelling of the tongue)   
Releases histamine
Treatment:
Anti Histamine
Epinephrine
34
Q

Multiple Myeloma

A

Cancel in the blood forming cells in the bone marrow.