Chapter 15- Drug Addiction

Question 1

What is it?

Answer 1

Drug-addicted individuals are those habitual drug users who continue to use a drug despite its adverse effects on their health and social life, and despite their repeated efforts to stop using it.

Question 2

Drug Tolerance, Drug Withdrawal Effects, and Physical Dependence

Answer 2

The fact that withdrawal effects are frequently opposite to the initial effects of the drug suggests that withdrawal effects may be produced by the same neural changes that produce drug tolerance

Question 3

Two categories of changes underlie drug tolerance:

Answer 3

metabolic and functional.

Question 4

metabolic tolerance

Answer 4

Drug tolerance that results from changes that reduce the amount of the drug getting to its sites of action

Question 5

functional tolerance

Answer 5

Drug tolerance that results from changes that reduce the reactivity of the sites of action to the drug

Question 6

cross tolerance

Answer 6

One drug can produce tolerance to other drugs that act by the same mechanism

Question 7

drug sensitization

Answer 7

tolerance may develop to some effects of a drug while sensitivity to other effects of the same drug increases. Increasing sensitivity to a drug is

Question 8

Drug Tolerance

Answer 8

is a state of decreased sensitivity to a drug that develops as a result of exposure to it. Drug tolerance can be demonstrated in two ways: by showing that a given dose of the drug has less effect than it had before drug exposure or by showing that it takes more of the drug to produce the same effect. In essence, what this means is that drug tolerance is a shift in the dose-response curve