Chapter 15 - Conditioned Drug Tolerance

Question 1

Central Assumption Theory

Answer 1

theory that conditional stimuli that predict drug administration come to elicit conditional responses opposite to the unconditional effects of the drug.

Question 2

Siegel

Answer 2

has termed these hypothetical opposing conditional responses conditioned compensatory responses. The theory is that conditional stimuli that repeatedly predict the effects of a drug come to elicit greater and greater conditioned compensatory responses; and those conditioned compensatory responses increasingly counteract the unconditional effects of the drug and produce situationally specific tolerance.

Question 3

Conditioned Drug Tolerance

Answer 3

refers to demonstrations that tolerance effects are maximally expressed only when a drug is administered in the same situation in which it has previously been administered

Question 4

Before and After Design

Answer 4

Most studies of contingent drug tolerance employ the before-and-after design. In before-and-after experiments, two groups of subjects receive the same series of drug injections and the same series of repeated tests, but the subjects in one group receive the drug before each test of the series and those in the other group receive the drug after each test of the series. At the end of the experiment, all subjects receive the same dose of the drug followed by a final test so that the degree to which the drug disrupts test performance in the two groups can be compared.