Chapter 15 Flashcards

1
Q

This is made up of DNA

A

Genes

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2
Q

If you know the genotype you know the

A

Phenotype

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3
Q

If you know what the genes are you know an organisms

A

Traits

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4
Q

If you know the DNA make up of an organism you know the

A

Proteins for it

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5
Q

The biochemical pathway to create Arginine has ____stepsin which each step requires a separate ______

A

5 ; enzyme

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6
Q

List similarities of DNA and RNA

A

Both nucleaic acid molecules

Both have phosphate backbone

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7
Q

List differences of DNA and RNA

A

> RNA sugar is ribose -DNA sugar is deoxyribose
RNA is slightly hydrophyllic move through cytoplasm
RNA has uracil base instead of the DNA thymine base
RNA single strand ; DNA double strand

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8
Q

What are the rna that are formed in transcription

A
mRNA
rRNA
tRNA
snRNA
microRNA
siRNA
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9
Q

Sequence of 3 nucleotide bases in the template strand of DNA codes for a specific amino acid

A

DNA triplet

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10
Q

Triplets are transcribed into ______ codon

A

mRNA

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11
Q

How many possible amino acids are there

A

20

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12
Q

When speaking of genetic code it is

A

Specific
Code is degenerate
Almost universal
Have special codons

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13
Q

What is the start codon where translation always starts

A

AUG

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14
Q

What are sequences of the stop codons where translation stops

A

UGA
UAA
UAG

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15
Q

What are the 3 steps in transcription

A

Initiation
Enlongation
Termination

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16
Q

Small RNA that are involved in gene expression

A

miRNA

siRNA

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17
Q

How does a retrovirus convert RNA to a DNA copy

A

Reverse transcriptase

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18
Q

This RNA carries DNA message to ribosome for processing of proteins

A

mRNA

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19
Q

This RNA has amino acids covalently attached to one end and an anticodon that can base pair with an mRNA

A

tRNA

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20
Q

Series of nucleotides grouped into blocks of information which corresponds to an amino acid

A

Codons

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21
Q

The genetic code is ______ which some amino acids are specified with more than one codon

A

Degenerate

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22
Q

For the most genetic code is universal. Which examples of living cells do not follow this universality

A

Mitochondria

Chloroplasts

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23
Q

How many codons total specify for amino acids

A

64

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24
Q

In prokaryotes the initiation of mRNA does not require______.

A

A primer

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25
Initiation of transcription requires two sites on DNA what are they
Promoter | Start site
26
This site forms a recognition and binding site for the RNA polymerase
Promoter
27
The site at which transcription begins
Start site
28
The polymerase needs this to end transcription
Terminator
29
In prokaryotes the mRNA produced by transcription begins to be translated before transcription is finished - they are _______. This can not occur in eukaryotes
Coupled
30
In eukaryotes transcription occurs in__________ and __________occurs in cytoplasm
Nucleus | Translation
31
This is a single transcription unit that encodes multiple enzymes in prokaryotes
Operon
32
How many RNA polymerase enzymes do prokaryotes and eukaryotes have in transcription
Prokaryotes-1 | Eukaryotes- 3
33
The RNA synethsized by RNA polymerase II is called the
Primary transcript
34
The primary transcript produces
Mature mRNA
35
The 5' cap and the 3' poly A tail are added to mRNA during eukaryotic transcription because
It protects it from degradation
36
Non coding DNA that interrupts the sequence of the gene
Introns
37
Coding sequences of DNA that are expressed
Exons
38
What percent of the human genome is made of introns and exons
24% | 1.5%
39
What complex recognizes the intron and exon junctions
snRNPs ( snurps)
40
The snRNPs cluster together to form a ______ which is responsible for the splicing of introns
Spliceosome
41
Or protein synthesis to proceed each ______ must be attached to tRNA with the correct ______.
Amino acid | Anticodon
42
Where does mRNA undergo translation to make a protein
Ribosomes
43
Ribosomes are made of
rRNA and proteins
44
What are the functions of the small and large unit in ribosomes
Small - decoding the transcribed message | Large- formation of peptide bonds by use of the enzyme peptidyl transferase
45
Su units only come together in
Translation
46
Name differences in prokaryotes and eukaryotes gene expression
Translation begins before transcription is completed ( coupled ) in prokaryotes while eukaryotes undergo modifications
47
In genetic code one codon
Consists of three bases and specifies a single amino acid
48
When the small and large subunits of the ribosomes come together they form ______.
3 slots APE
49
When the elongation step in protein synthesis reaches a stop codon what attaches to this codon
Release factor
50
What does the release factor initiates in protein synthesis
Release the polypeptide ( protein) mRNA is released Subunits beak apart to form again elsewhere
51
A mutation that alters a single base by either substitution deletion addition
Point mutation
52
This type of point mutation is the substitution of one base pair for another which may or may not alter the amino acid encoded
Base substitution mutation
53
This point mutation is the addition or deletion of a single base in this case it can alter the reading in the mRNA which could lead to altering most protein as well as early termination of translation
Frame shift mutation
54
Mutations altering the structure of the chromosomes
Chromosomal mutation
55
Deletion in a chromosome mutation is not
Reversible
56
This mutation changes the codon to a different codon that changes the amino acid
Missense mutation
57
This mutation changes a codon to a stop codon
Nonsense mutation
58
This type of chromosomal mutation an entire section of chromosome and entire genes are lost
Deletion
59
In this chromosomal mutation is duplicated and new results in 2 copies of the gene
Duplication
60
This chromosomal mutation a section breaks off and reattached to different chromosome
Translocation
61
Section is broken off in two places rotates 180* and reattaches where broken
Inversión | May effect how genes are expressed