Chapter 148- Vascular and lymphatic Cutaneous Diseases Flashcards
Ischemic dermopathy characterized by violaceous reticular or ‘netlike’ mottling of skin
Livedo
Primary, symmetric, reversible, and uniform discoloration affecting young to middle aged females that is benign
Livedo reticularis
Discoloration of livedo is aggravated by
Cold exposure
Livid rings are most pronounced on ___, yet the ___& ___ can also be affected
LE»_space; abdomen & UE
Painful ulcerations of ankles and forefeet
Livedoid vasculitis
Both livedo reticularis and racemosa are associated with vasospastic digits or acrocyanosis.
True or False
True
Livedo racemosa + aphasia + lateralizing neurologic signs
Sneddon syndrome
__ arteriolar vasospasm leads to livedo reticularis;
__ arteriolar vasospasm leads to livedo racemosa
Physiologic
Protracted
__ is warranted in patient with livedoid vasculopathy
Thrombophilia panel
Marker for predicting multisystem thrombosis in APAS
Livedo racemosa
40% of APAS Patients present with this initial sign
Livedo racemosa
Independent risk factor for pregnancy loss in the absence of APAS
Livedo racemosa
Treatment for livedo reticularis
Cold avoidance
Episodes of erythromelalgia can be triggered by (3)
- Dependency of the limb
- Wearing of tight socks, shoes
- Ingestion of alcohol or spicy foods
Secondary erythromelalgia occurs at any age and female predilection.
True or False
False, third decade with equal sex distribution
Mechanisms for pathogenesis of erythromelalgia
- AV shunting
2. Small fiber neuropathy
Secondary erythromelalgia is associated with
Polycythemia
Thrombocythemia
Autoimmune disorders
CCBs and B blockers are very effective for erythromelalgia.
True or False
False, minimally effective
Thromboangiitis obliterans affect __&__ arteries and veins in extremities
Medium & small
Thromboangiitis obliterans is more common in __ with onset at age of ___ years old
Men; 20 to 40
Involvement of multiple limbs is atypical for Thromboangiitis obliterans.
True or False
False, typical
40% of Thromboangiitis obliterans presents with
Migratory superficial thrombophlebitis
Distal pulses (3) absent in Thromboangiitis obliterans
Dorsalis pedis
Posterior tibial
Ulnar
Increased prevalence of (4) HlA genotypes have been observed in Thromboangiitis obliterans
HLA A9
HLA A54
HLA B5
First line therapy for symptom relief of Thromboangiitis obliterans
Local wound care and analgesics
Improves ulcer healing and eliminates rest pain for Thromboangiitis obliterans
Iloprost
Smoking 1-2 cigarettes, using nicotine replacements is allowable for Thromboangiitis obliterans.
True or False
False, keep the disease active
Recommended diagnostic test for lymphedema
Isotopic lymphoscintigraphy
__ is preferred Dx modality for lymphedema due to its ability to detect water
MRI
___ reduces capillary filtration as well as fibrotic tissue deposition
Coumarin
Common complications of longstanding lymphedema (4)
Cellulitis
Erysipelas
Tinea pedis
Lymphangitis
Not used as treatment for lymphedema ws it may worsen the condition
Diuretics
Therapeutic options for lymphedema (6)
Compression Elevation Exercise Manual lymphatic drainage Skin care Surgery