Chapter 13 cont'd and 14 Flashcards

1
Q
Cancers of the female reproductive tract
Largely a std
Like the HPV virus
Screening: ? test
Treatment: Surgery, chemotherapy, radiation
A

Cervical cancer

Pap test

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2
Q
Uterine, or endometrial, cancer
Most often occurs after ?
Treatment is surgery
? removal of the uterus
With early detection, ? survival rate after 5 years
? if cancer has spread beyond the uterus
A

55
Hysterectomy
95%
67%

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3
Q

Ovarian cancer
•Difficult to detect and diagnose; no warning signs
•Risk factors: age, never having been ?, family history of breast or ovarian cancer, obesity, genetics, and a high number of ?
•Treatment is ? removal of the ovaries, the fallopian tubes, and the uterus
•Radiation and chemotherapy are sometimes used
•Survival rate after 5 years is over 90% for a localized tumor but is only ?% for all stages

A
  • pregnant, ovulations
  • surgical
  • 47%
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4
Q
?- Most common type of cancer, but many types are easily curable
Risk factors:
•Exposure to ultraviolet (UV) radiation
•Sunburns and suntans, especially in childhood
•Fair skin
•? ozone
•Moles
•Spending time at high ?
•Family history
A
  • Skin cancer
  • Depleted
  • altitudes
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5
Q

-Types of skin cancer
-most dangerous form
Prevention:
•Avoid long-term ? to sunlight
•Protection from sun: ? and clothing
Detection and treatment:
•Signs in skin ?: ABCDE

A
  • Basal cell carcinoma
  • Squamous cell carcinoma
  • Melanoma
  • overexposure
  • sunscreen
  • lesions
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6
Q

-rare, most common cancer in U.S. men aged 20 to 35
-Risk factors: European Americans; fathers who had ?; undescended ?
-treatment: ? is removed and, if the ? has spread, chemotherapy is used
5 year survival rate is ?

A
  • Testicular cancer
  • testicular cancer, testicles
  • testicle, tumor
  • 96%
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7
Q

-is the body’s collective set of defenses against infection
-protects us not just from ? (disease-causing organisms) but also from cancer
-? and ? barriers are the first line of defense
•Skin
•? membranes
•? tract, lined with both mucous membranes and cilia

A
  • immune system
  • pathogens
  • physical, chemical
  • mucous
  • respiratory
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8
Q
Beyond surface barriers, the immune system operates through a network of billions of ? blood cells
•Actually two interacting systems: the ? immune system (first to respond) and the ? immune system
Cells of the innate immune system
•?
•Eosinophils
•Macrophages
•Natural killer cells
•? cells
A
  • white
  • innate, adaptive
  • neutrophils, dendritic
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9
Q

Immune response
Phase 1, ?:dendritic cells are drawn to the site
•Phase 2, ?: helper T cells multiply
•Production of killer ? and ? cells
•?: special growth stimulants
•Phase 3, ?: •Activated T and B cells transform into memory and effector cells
•Effector cells mediate elimination of the ?
•Memory B cells or ?-producing plasma cells mark extracellular pathogens for destruction
•Phase 4, ?: restores “resting” levels of B and T cells
-some memory T and B cells remain

A
  • recognition
  • proliferation
  • T and B
  • cytokines
  • elimination
  • pathogen, antibody
  • slowdown
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10
Q
  • Usually, after an infection, a person has ? to the same pathogen
  • Memory T and B cells continue to circulate in the blood and ? system
  • ?immunity to infection acquired by the activation of ?-specific lymphocytes in response to infection or immunization
A
  • immunity
  • lymphatic
  • adaptive immunity, antigen
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11
Q

-?-Vessels that carry lymph; and certain organs and structures
•?, lymph nodes
•Vessels pick up ? fluid from body tissues and clear it of debris and pathogens
•As the immune response progresses, a lymph node actively involved in ? infection may fill with cells and swell—thus physicians use the location of swollen lymph nodes as a clue to an infections location

A
  • lymphatic system
  • spleen
  • excess
  • fighting
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12
Q

-?-such as by administering a vaccine, primes the body to remember an encounter with a specific antigen

A

-Immunization

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13
Q
? -result from a ? and overactive immune system
•Reaction to a harmless substance as if it were a harmful pathogen
•? elicit an exaggerated immune response
•Pollen
•Animal ?
•Dust mites and cockroaches
•? and mildew
•Foods
•Insect stings
A
  • Allergies, hypersensitive
  • Allergens
  • dander, molds
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14
Q

?-Part of the body’s response is to release large amounts of ?, a chemical involved in some cases of inflammation as well as allergy
•In some people, an allergen can trigger an ? attack
•Causes ?, shortness of breath, and coughing
•Most serious kind of allergic reaction is ?, characterized by difficulty breathing, low blood pressure, heart arrhythmia, seizure, and sometimes death
•Treatment requires immediate injection of ?

A
  • Allergic response
  • histamine
  • asthma, wheezing
  • anaphylaxis
  • epinephrine
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15
Q

First phase of infection: the ? period
•May not have symptoms; may be contagious
Second and third phases: may “feel a cold coming on” symptoms first appear during the ? period
Many symptoms are due to the immune response
You may be contagious before you have symptom

A

incubation

prodromal

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16
Q

The Chain Infection
Links in the chain:
(1) ?:disease causing carcinogen
(2) ?: natural environment of the pathogen - person, animal, or environmental component
(3) ?: discharge
(4) ?: direct and indirect
?: carrier of the pathogen from one host to another
(5) ?:skin penetration; inhalation; ingestion
Pathogens that enter the bloodstream or lymphatic system cause a ?
(6) New ?

A
Pathogen
Reservoir
Portal of exit
Means of transmission
Vector
Portal of entry
Systemic infection
host
17
Q

?: microscopic single-celled organisms
•?: an inflammation of the lungs
•?: inflammation of the meninges, the protective membranes of the brain and spinal cord
•?: strep throat and other streptococcal infections
•?: toxic shock syndrome and other staphylococcal infections
•? which usually affects the lungs
•Tick-borne infections
•Other bacterial infections, including ulcers, tetanus, C. diff, pertussis, urinary tract infections, and travelers’ diarrhea (TD

A
Bacteria
Pneumonia
Meningitis
Streptococcus
Staphylococcus
Tuberculosis
18
Q
Antibiotic treatments
•?: drugs that either inhibit the growth of bacteria or kill them
•? has resulted from overuse and misuse
•Proper usage:
•Don’t take an antibiotic every time you are ?
•Use antibiotics as directed
•Never take an antibiotic without a ?
•Avoid “antibacterial” soap products
A

Antibiotics
Antibiotic resistance
sick
prescription

19
Q

?: a microscopic organism that replicates inside the cells of another organism; cause of most contagious diseases
•Common cold; ?; measles, mumps, and rubella
•Chickenpox, cold sores, other ? infections, including the varicella-zoster virus, herpes simplex virus (HSV) types 1 and 2, and Epstein-Barr virus (EBV)
•Viral ?: HAV, HBV, HCV
•Human papillomavirus (HPV

A

Virus
influenza
herpesvirus
hepatitis

20
Q

?: an organism that is reproduced by spores
•Yeast infections, athletes foot, jock itch, ringworm
?: microscopic single-celled organisms
•? and giardiasis
? :largest organisms that can enter the body to cause infection
•Tapeworm, hookworm, pinworm

A

Fungus
Protozoa, malaria
Parasitic worms

21
Q

? diseases
•Immune system targets or destroys specific tissues
? system and cancer
•Some types of cancer suppress immune responses
•Immunotherapy

A

Autoimmune

Immune

22
Q
? - are spread from person to person mainly through sexual activity
•Also still called ?
Seven pose major health threats:
•HIV/AIDS
•?
•Gonorrhea
•Human papillomavirus (HPV)
•Herpes
•Hepatitis
•?
A

STIs
STDs
Chlamydia
Syphilis

23
Q

?- causes ?
-primary cause of death in Africa
In the U.S. today, about ? people are living with HIV; ?% of these people are not aware of their HIV status

A

HIV, AIDS
1 million
15%

24
Q

? -is a chronic viral infection that progressively damages the body’s immune system
•HIV attacks and invades ?, macrophages, and other essential elements of the immune system
•It enters a human cell and converts its own genetic material, RNA, into DNA
•Viral DNA produces new copies of HIV and ? immune function
•Signaled by the loss of CD4 T cells

A

HIV infection
CD4 T-cells
reduce

25
Q

?: flulike symptoms; highly infectious
Chronic ? stage (latency phase)
•Can last ? to ? years in untreated adults
•Virus infects and destroys cells of the immune system
•Person remains infectious (even if symptom-free)
AIDS is diagnosed when the number of CD4 cells drops below a certain level
•? (secondary) infections take hold

A

Primary infection phase
asymptomatic
2 to 20
Opportunistic

26
Q

HIV lives only within ? and ?
•Transmitted through blood products, semen, vaginal and ? secretions, and breast milk
•Cannot live in ?, water, or on objects or surfaces
Three primary means of transmission: •Specific kinds of ? contact
•Direct ? to infected blood •Contact between an HIV infected woman and her child through pregnancy, childbirth, ?, or premastication

A

cells, body fluids
cervical, air
sexual, exposure, breastfeeding

27
Q

Primary HIV infection: flulike symptoms within a few ? or ?
•After these initial symptoms, ? for the first months or years
New symptoms develop as the immune system weakens
•Opportunistic infections occur
•? , a fungal infection
•? sarcoma
•Persistent vaginal yeast infections in women
•Tuberculosis (TB) is increasingly reported

A

days, weeks
asymptomatic
Pneumocystis pneumonia
Kaposi’s sarcoma

28
Q

Three general types of diagnostic tests:
•HIV ? tests
•Combination HIV antigen/? tests
•(NATs)
If ?, the next step is to determine the disease’s severity, and the viral load is monitored
•Certain infections or a damaged immune system leads to an AIDS diagnosis
All diagnosed cases of HIV or AIDS must be reported to public health authorities

A

antibody
antibody
Nucleic acid tests
HIV positive

29
Q

?- (PrEP) is a drug that can be used with other methods to reduce risk

A

preexposure prophylaxis

30
Q

? - most prevalent bacterial STI in the U.S.
•? trachomatis
•Untreated, can lead to PID and increases risk of infertility and ? (tubal) pregnancy
•? is the most common cause of epididymitis and ?
•Infants of infected mothers can acquire the infection in the birth canal
•Antibiotics are the usual treatment
•Testing and treatment for both partners, often using expedited partner therapy

A

Chlamydia
ectopic
urethritis

31
Q

? - flourishes in mucous membranes
•Neisseria ?
•Often has no symptoms, especially in women
•Women: frequent ? during urination, menstrual irregularities, pelvic pain, discharge; and can cause urethritis, cervicitis, and PID
•Men: epididymitis and ?
•Infants: gonococcal ?
Treatment: a combination of antibiotics
•Increasing drug resistance is a major concern

A

Gonorrhea

burning, proctitis, conjunctivitis

32
Q

? - (PID) is a major complication of untreated chlamydia or gonorrhea
•Initial infection travels beyond the cervix
•Leading cause of infertility in young women
•Symptoms vary greatly
•Some asymptomatic; others have abdominal pain, fever, chills, nausea, vomiting, abnormal vaginal bleeding
Treatment with antibiotics must be started immediately
•? may be used to confirm the diagnosis
•Partners must also be treated

A

Pelvic inflammatory disease

Laparoscopy

33
Q

? - can cause several disease, including common warts, genital warts, and genital cancers (virtually all cervical cancers)
•Most common STI in the United States
•More than ?% infected by age 50
•Vaccines recommended for girls and boys
•Symptoms: small bumps to large, ? growths
•Most people have no symptoms and are not aware they are contagious
•Treatment: reduction of warts
•Regular Pap tests for all women recommend

A

Human papillomavirus
80%
warty

34
Q

Up to ? in ? adults in the U.S. has genital herpes
•HSV 1: associated with ?, fever blisters
•Usually acquired through oral–genital contact
•HSV 2: almost always ?
•Spread whether active sores or asymptomatic
•Remains in the body for life
•Symptoms: up to ?% have none
•Primary outbreak 2 to 20 days after sex with an infected partner: flulike symptoms, genital lesions
•Symptoms subsequently triggered by stress, fatigue, illness •Antiviral drugs can shorten duration and severity

A

1 in 6
cold sores
sexually transmitted
90%

35
Q

? - is an inflammation of the liver
•One type is caused by hepatitis B virus (HPB)
•Transmission: semen, saliva, blood, urine
•Sexual exposure, injection drug use, nonsexual close contact
•Vaccine is available
•? - is of particular concern for people who engage in anal sex
•Vaccine is available
•? - is associated with high-risk sexual encounters
•No vaccine

A

Hepatitis
Hepatitis A
Hepatitis C

36
Q

There is no cure for ? and no specific treatment for acute infections

A

HBV

37
Q

?- caused by Treponema pallidum, can now be treated effectively with antibiotics
•Usually acquired through sexual contact
•Pathogen breaks through openings in skin or mucous membranes; and an infected pregnant woman can pass it to her fetus
•Symptoms •Primary syphilis: ?, 10 to 90 days postexposure
•Secondary syphilis: 3 to 6 weeks after chancre, body rash, flulike symptoms
•Late or tertiary syphilis: damage to organs, ?, blindness, death
•Treatment
•All stages can be treated by antibiotics, but damage from late syphilis can be permanent

A

Syphilis
chancres
dementia

38
Q

?, often called trich, is the most prevalent nonviral STI in the United States
?-Abnormal vaginal discharge caused by unhealthy vaginal bacteria
? - Contagious parasitic infection

A

Trichomoniasis
Bacterial vaginosis
pubic lice (crabs) and scabies