chapter 13 Flashcards
The first layer of protection for the central nervous system is
the hard bony skull and vertebral column.
The second protective layer of the CNS
is the meninges, three membranes that lie between the bony encasement and the nervous tissue in both the brain and spinal cord
The final protective layer of the CNS is
cerebrospinal fluid
The spinal cord is located within
the vertebral canal of the vertebral column
meninges (me-NIN-jēz; singular is meninx [MĒ-ninks])
three distinct protective, connective tissue coverings that encircle the spinal cord and brain.
From superficial to deep the menegies are .
the (1) dura mater, (2) arachnoid mater, and (3) pia mater
epidural space (ep′-i-DOO-ral),
a space between the dura mater and the wall of the vertebral canal
There is a cushion layer of fat in the
epidural space
Dura mater (DOO-ra MĀ-ter = tough mother).
The most superficial of the three spinal meninges is a thick strong layer composed of dense irregular connective tissue.
Arachnoid mater (a-RAK-noyd MĀ-ter; arachn- = spider; - oid= similar to).
This layer, the middle of the meningeal membranes, is a thin, avascular covering comprised of cells and thin, loosely arranged collagen and elastic fibers
Between the dura mater and the arachnoid mater is a thin _________ which contains interstitial fluid.
subdural space
Pia mater (PĒ-a MĀ-ter; pia = delicate).
This innermost meninx is a thin transparent connective tissue layer that adheres to the surface of the spinal cord and brain.
Within the pia mater are
many blood vessels that supply oxygen and nutrients to the spinal cord.
denticulate ligaments (den-TIK-ū-lāt = small tooth),
Triangular-shaped membranous extensions of the pia mater suspend the spinal cord in the middle of its dural sheath
Extending along the entire length of the spinal cord, the denticulate ligaments
protect the spinal cord against sudden displacement that could result in shock.
Between the arachnoid mater and pia mater is a space,
the subarachnoid space, which also contains shock-absorbing cerebrospinal fluid.
Why does the spinal cord not extend to the end of the spine
Elongation of the spinal cord stops around age 4 or 5, but growth of the vertebral column continues. Thus, the spinal cord does not extend the entire length of the adult vertebral column.
the cervical enlargement,
extends from the fourth cervical vertebra (C4) to the first thoracic vertebra (T1). Nerves to and from the upper limbs arise from the cervical enlargement.
the lumbosacral enlargement,
extends from the ninth to the twelfth thoracic vertebra. Nerves to and from the lower limbs arise from the lumbar enlargement.
Inferior to the lumbar enlargement, the spinal cord terminates as a tapering, conical structure called the __________which ends at the level of the _______________
conus medullaris
intervertebral disc between the first and second lumbar vertebrae (L1–L2) in adults.
Arising from the conus medullaris is the _______________which is ______________
filum terminale (FĪ-lum ter-mi-NAL-ē = terminal filament),
an extension of the pia mater that extends inferiorly, fuses with the arachnoid mater and dura mater, and anchors the spinal cord to the coccyx.
In a spinal tap (lumbar puncture),
a local anesthetic is given, and a long hollow needle is inserted into the subarachnoid space to withdraw cerebrospinal fluid (CSF)
Spinal nerves are
the paths of communication between the spinal cord and specific regions of the body.
How many pairs of nerves are at each segment of the spine
There are 8 pairs of cervical nerves (represented in Figure 13.2 as C1–C8), 12 pairs of thoracic nerves (T1–T12), 5 pairs of lumbar nerves (L1–L5), 5 pairs of sacral nerves (S1–S5), and 1 pair of coccygeal nerves (Co1).
Two bundles of axons, called roots,
connect each spinal nerve to a segment of the cord by even smaller bundles of axons called rootlets
The posterior root and rootlets contain
only sensory axons, which conduct nerve impulses from sensory receptors in the skin, muscles, and internal organs into the central nervous system.
spinal (dorsal root) ganglion
A swelling in the posterior root which contains the cell bodies of sensory neurons.
The anterior root and rootlets contain
axons of motor neurons, which conduct nerve impulses from the CNS to effectors (muscles and glands).
cauda equina
The roots of these lower spinal nerves angle inferiorly alongside the filum terminale in the vertebral canal like wisps of hair.
As spinal nerves branch from the spinal cord,
they pass laterally to exit the vertebral canal through the intervertebral foramina between adjacent vertebrae.
The spinal cord extends
from the medulla oblongata of the brain to the superior border of the second lumbar vertebra.
A transverse section of the spinal cord
reveals regions of white matter that surround an inner core of gray matter
The white matter of the spinal cord consists primarily of
bundles of myelinated axons of neurons.
The anterior median fissure
a wide groove on the anterior (ventral) side of the spinal cord
The posterior median sulcus is
a narrow furrow on the posterior (dorsal) side of the spinal cord
The gray matter of the spinal cord is shaped like the letter H or a butterfly; it consists of
dendrites and cell bodies of neurons, unmyelinated axons, and neuroglia.
The gray commissure (KOM-mi-shur)
forms the crossbar of the H of the gray matter
the central canal
extends the entire length of the spinal cord and is filled with cerebrospinal fluid. At its superior end, the central canal is continuous with the fourth ventricle (a space that contains cerebrospinal fluid) in the medulla oblongata of the brain.
Anterior to the gray commissure is the anterior white commissure, which
connects the white matter of the right and left sides of the spinal cord.
In the gray matter of the spinal cord and brain, clusters of neuronal cell bodies form functional groups called
nuclei.
The posterior gray horns contain
axons of incoming sensory neurons as well as cell bodies and axons of interneurons
The anterior gray horns contain
somatic motor nuclei, which are clusters of cell bodies of somatic motor neurons that provide nerve impulses for contraction of skeletal muscles.
The lateral gray horns contain
autonomic motor nuclei, which are clusters of cell bodies of autonomic motor neurons that regulate the activity of cardiac muscle, smooth muscle, and glands.
The anterior and posterior gray horns divide the white matter on each side into three broad areas called
funiculi
tracts
distinct bundles of axons having a funiculus origin or destination and carrying similar information. These bundles, which may extend long distances up or down the spinal cord
Sensory (ascending) tracts consist of
axons that conduct nerve impulses toward the brain
Tracts consisting of axons that carry nerve impulses from the brain are called
motor (descending) tracts.
How does the does the spinal cord allow sensory input and motor output to be processed by the spinal cord
- Sensory receptors detect a sensory stimulus.
- Sensory neurons convey this sensory input in the form of nerve impulses along their axons, which extend from sensory receptors into the spinal nerve and then into the posterior root. From the posterior root, axons of sensory neurons may proceed along three possible paths (see steps 3, 4, and 5).
- Axons of sensory neurons may enter the posterior gray horn and then extend into the white matter of the spinal cord and ascend to the brain as part of a sensory tract.
- Axons of sensory neurons may enter the posterior gray horn and synapse with interneurons whose axons extend into the white matter of the spinal cord and then ascend to the brain as part of a sensory tract.
5, Axons of sensory neurons may enter the posterior gray horn and synapse with interneurons that in turn synapse with somatic motor neurons that are involved in spinal reflex pathways. Spinal cord reflexes are described in more detail later in this chapter.
How does the spinal cord allow motor outouts to be processed by the spinal cord
1.Motor output from the spinal cord to skeletal muscles involves somatic motor neurons of the anterior gray horn. Many somatic motor neurons are regulated by the brain. Axons from higher brain centers form motor tracts that descend from the brain into the white matter of the spinal cord. There they synapse with somatic motor neurons either directly or indirectly by first synapsing with interneurons that in turn synapse with somatic motor neurons.
2. When activated, somatic motor neurons convey motor output in the form of nerve impulses along their axons, which sequentially pass through the anterior gray horn and anterior root to enter the spinal nerve. From the spinal nerve, axons of somatic motor neurons extend to skeletal muscles of the body.
3. Motor output from the spinal cord to cardiac muscle, smooth muscle, and glands involves autonomic motor neurons of the lateral gray horn. When activated, autonomic motor neurons convey motor output in the form of nerve impulses along their axons, which sequentially pass through the lateral gray horn, anterior gray horn, and anterior root to enter the spinal nerve.
4. From the spinal nerve, axons of autonomic motor neurons from the spinal cord synapse with another group of autonomic motor neurons located in the peripheral nervous system (PNS). The axons of this second group of autonomic motor neurons in turn synapse with cardiac muscle, smooth muscle, and glands. You will learn more about autonomic motor neurons when the autonomic nervous system is described in Chapter 15.
Sensory input is conveyed
from sensory receptors to the posterior gray horns of the spinal cord
motor output is conveyed
from the anterior and lateral gray horns of the spinal cord to effectors (muscles and glands).
the amount of white matter decreases
from cervical to sacral segments of the spinal cord.
why does the amount of white matter decreases from cervical to sacral segments of the spinal cord.
(1) As the spinal cord ascends from sacral to cervical segments, more ascending axons are added to spinal cord white matter to form more sensory tracts. (2) As the spinal cord descends from cervical to sacral segments, the motor tracts decrease in thickness as more descending axons leave the motor tracts to synapse with neurons in the gray matter of the spinal cord.
Describe the characteristics of the cervical segment of the spinal cord
Relatively large diameter, relatively large amounts of white matter, oval; in upper cervical segments (C1–C4), posterior gray horn is large but anterior gray horn is relatively small; in lower cervical segments (C5 and below), posterior gray horns are enlarged and anterior gray horns are well developed.
Describe the characteristics of the thoracic segment of the spinal cord.
Small diameter due to relatively small amounts of gray matter; except for first thoracic segment, anterior and posterior gray horns are relatively small; small lateral gray horn is present.
Describe the characteristics of the lumbar segment of the spinal cord.
Nearly circular; very large anterior and posterior gray horns; small lateral gray horn is present in upper segments; relatively less white matter than cervical segments.
Describe the characteristics of the sacral segment of the spinal cord.
Relatively small, but relatively large amounts of gray matter; relatively small amounts of white matter; anterior and posterior gray horns are large and thick.
Describe the characteristics of the coccygeal segment of the spinal cord.
Resembles lower sacral spinal segments, but much smaller.
Spinal nerves
are associated with the spinal cord and, like all nerves of the peripheral nervous system (PNS), are parallel bundles of axons and their associated neuroglial cells wrapped in several layers of connective tissue.
The 31 pairs of spinal nerves are named and numbered according to
the region and level of the vertebral column from which they emerge
The first cervical pair of spinal nerves emerges from the spinal cord
between the occipital bone and the atlas
Spinal nerves C1–C7 exit the vertebral canal
above their corresponding vertebrae.
Spinal nerve C8 exits the vertebral canal
between vertebrae C7 and T1
Spinal nerves T1–L5 exit the vertebral canal
below their corresponding vertebrae.
From the spinal cord, the roots of the sacral spinal nerves (S1–S5) and the coccygeal spinal nerves.
enter the sacral canal, the part of the vertebral canal in the sacrum
spinal nerves S1–S4 exit the sacral canal via
the four pairs of anterior and posterior sacral foramina, and spinal nerves S5 and Co1 exit the sacral canal via the sacral hiatus.
The posterior and anterior roots unite to form a spinal nerve at the
intervertebral foramen.
Because the posterior root contains sensory axons and the anterior root contains motor axons, a spinal nerve is classified as a
mixed nerve
Each spinal nerve and cranial nerve consists of
many individual axons and contains layers of protective connective tissue coverings
Individual axons within a nerve, whether myelinated or unmyelinated, are wrapped in
endoneurium (en′-doˉ -NOO-rē-um; endo- = within or inner; -neurium = nerve), the innermost layer.
Groups of axons with their endoneurium are held together in bundles called
nerve fascicles, each of which is wrapped in perineurium (per′-i-NOO-rē-um; peri- = around), the middle layer.
The outermost covering over the entire nerve is the
epineurium (ep′-i-NOO-rē-um; epi- = over). It consists of fibroblasts and thick collagen fibers.
Three layers of connective tissue wrappings protect axons:
Endoneurium surrounds individual axons, perineurium surrounds bundles of axons (nerve fascicles), and epineurium surrounds an entire nerve.
A short distance after passing through its intervertebral foramen,
a spinal nerve divides into several branches. These branches are known as rami
The posterior (dorsal) ramus (RĀ-mus; singular form) serves
the deep muscles and skin of the posterior surface of the trunk.
The anterior (ventral) ramus serves
the muscles and structures of the upper and lower limbs and the skin of the lateral and anterior surfaces of the trunk.
meningeal branch (me-NIN-jē′-al).
This branch reenters the vertebral cavity through the intervertebral foramen and supplies the vertebrae, vertebral ligaments, blood vessels of the spinal cord, and meninges
The branches of a spinal nerve are
the posterior ramus, the anterior ramus, the meningeal branch, and the communicating rami.
Axons from the anterior rami of spinal nerves, except for thoracic nerves T2–T12,
do not go directly to the body structures they supply.
plexus
networks on both the left and right sides of the body that join with various numbers of axons from anterior rami of adjacent nerves.
The principal plexuses are the
cervical plexus, brachial plexus, lumbar plexus, and sacral plexus. A smaller coccygeal plexus is also present
The anterior rami of spinal nerves T2–T12
do not enter into the formation of plexuses and are known as intercostal nerves or thoracic nerves.
After leaving its intervertebral foramen, the anterior ramus of nerve T2 innervates the
intercostal muscles of the second intercostal space and supplies the skin of the axilla and posteromedial aspect of the arm.
Nerves T3–T6 .
extend along the costal grooves of the ribs and then to the intercostal muscles and skin of the anterior and lateral chest wall
Nerves T7–T12 supply
the intercostal muscles and abdominal muscles, along with the overlying skin.
dermatome
The area of the skin that provides sensory input to the CNS via one pair of spinal nerves or the trigeminal (V) nerve
Knowing which spinal cord segments supply each dermatome makes it possible to
locate damaged regions of the spinal cord
The cervical plexus (SER-vi-kul) is formed by
the roots (anterior rami) of the first four cervical nerves (C1–C4), with contributions from C5 (Figure 13.8). There is one on each side of the neck alongside the first four cervical vertebrae.
The cervical plexus supplies
the skin and muscles of the head, neck, and superior part of the shoulders and chest. The phrenic nerves arise from the cervical plexuses and supply motor fibers to the diaphragm. Branches of the cervical plexus also run parallel to two cranial nerves, the accessory (XI) nerve and hypoglossal (XII) nerve.
the Lesser occipital nerve
originates from C2 and is a sensory branch that serves the Skin of scalp posterior and superior to ear.
Great auricular nerve
originates from C2-C3 and is a sensory branch that serves the Skin anterior, inferior, and over ear, and over parotid glands.
Transverse cervical branch
a senxory branch that Originates from C2-C3 and serves the Skin over anterior and lateral aspect of neck.
Supraclavicular branch
A sensory branch originating from C3-C4 that serves the Skin over superior portion of chest and shoulder.
Ansa cervicalis
Motor branch that Divides into superior and inferior roots.
Superior Root
Motor branch that originates at C1 and controls the Infrahyoid and geniohyoid muscles of neck.
Inferior Root
Motor branch that originates at C2-C3 and controls the Infrahyoid muscles of the neck
Phrenic
Motor branch that originates at C3-C5 and controls the diaphragm
Segmental branches
Motor branches that originate at C1-C5 and control Prevertebral (deep) muscles of neck, levator scapulae, and scalenus medius muscles.