Chapter 1.12 Yersinia, Francisella, Brucella, And Pasteurella Flashcards
What are the common characteristics of Yersinia, Francisella, Brucella, and Pastrurella?
Gram-negative rods (bacilli)
Zoonotic diseases (primarily diseases of animals)
Very virulent and can penetrate any body area they touch
Are facultative intracellular organisms
Where do Yersinia, Franccisella, Brucella, and Pasteurella migrate to?
Regional lymph nodes, bloodstream, liver, spleen, lungs
What is the immune response against facultative intracellular organisms?
Cell-mediated and delayed type hypersensitivity reaction
What bacteria is associated with rats?
Yersinia PESTis (rats are PESTS)
What is another name for Yersinia pestis?
Bubonic plague
What are the virulence factors of Yersinia pestis?
Fraction 1, V antigen, W antigen
What type of bacteria is Yersinia pestis?
Gram-negative bacterium with bipolar staining pattern
What mammals fall prey to Yersinia pestis?
Wild rodents, domestic city rodents, and humans
What does the word “boubon” mean in Greek?
“Groin” - relates to bubonic plague because these are the lymph nodes that Yersinia pestis goes to first
What is the morphology of lymph nodes infected with Yersinia pestis?
Swell like eggs and become hot, red, and painful
What is the skin morphology of a person infected with Yersinia pestis?
Blackish discoloration
*lead to people calling the bubonic plague the “Black Death”
What US locations should be considered for Yersinia pestis?
Arizona and New Mexico
What bacteria causes Tularemia?
Francisella tularensis
What is tularemia?
Resembles bubonic plague and is acquired from handling infected rabbits, tick bites and deerflies
What is the Mneumonic for Francisella tularensis?
Francis (Francisella) the rabbit (rabbit vector) is playing in the Tulips (Tularensis)
One ear has a tick and the other has a deer flu