chapter 11 Flashcards
substance related disorders
- pattern of recurrent substance use
- cogntive, behavioral, physiological symptoms
- changes in brain circuits
- to diagnose: must have 2-11 symptoms over 12mp
- mild (2 sympt) to severe (6+ sympt)
- extremely rewarding but just feel good fast
- potential for addiction high because dont have to work for rewards
alcohol
- central ns depressant: initally depresses inhibitory centers in brain, influences NTs like gaba, glutamate, serotonin
- effects of chronic alcohol use: alcohol withdrawal, brain conditions, fasd, liver disease
stimulants: amphetamines
- elation, vigor, reduced fatigue
- increased hr, bp, respiration, insomnia, loss of appetite
- blocks reuptake fo 5ht, ne, da, increases stimulation of da neurons
- severe intoxication/overdose: panic, agitation, stimulant, psychosis
- addictive
- tolerance and dependence common
- withdrawal like depression
- sometimes given in low doses for adhd
stimulants: cocaine
- short lived sensations of elation, vigor, reduced fatigue, increased alertness
- increases bp, hr, insomnie, loss of appetite
- blocks reuptake of 5ht, ne, da, increases stimulation of da neurons in pleasure pathway, followed by a crahs
- highly addictive but develops slowly
- consequences: paranoia, depressed mood, psychological symptoms
- crack a problem bc quick high and cheap
opiates and opiods
opoids
- natural and synthetic substances with narcotic effects
- heroin, codeine, morphine, oxycodone, fentanyl
effects
- binds to opioid receptors, activates enkephalines and endorphines, increased dopamine in brains pleasure centres
- low doses: euphoria, drowsiness, slowed breathing
- high doses: result in death quickly from respiration suppression
- quick tolerance
- withdrawal: nausea, vomiting, chills, doesnt gett better until 72h later but starts 8h after dose
hallucinogens
- change perception
- may produce delusions, paranoia, hallucinations, dissociative expereinces, altered sensory perception
- lsd, shrooms, pcp
- mimics nts
- tolerance builds quickly
- withdrawal uncommon
cannabis
- associated with mood swings, heightened sensory experiences, dream like states, large doses: paranoia and hallucinations
- frequent users get impaired memory, concentration, reduced self esteem, relationship impairment
- neurological effects on development: alterations on matter, volume, neuronal connectivity, leads to behavioural effects
- withdrawal syndrome: mood disturbances and physical symptoms
family and genetic influences
- strong genetic component
- genes that may influence alcoholism and alcohol consumption levels
- differences found in alcohol metabolism
- polygenetic
- less alcoholism in groups that have a harder time metabolizing
neurobiological influences
- addiction involes several brain regions and neurocircuitry related to reward, motivation, memory, impulse control
- activates pleasure pathway: da system, nts that are responsible for anxiety may be inhibited by substances
psychological dimensions-
- positive and negative reinforcements: pleasurable effects of substances, self medication, use to cope
- opponent process theory: uses reinforcement model to explain continued use and abuse
- role of expectancy: expectancies regarding effects and use have indirect influence on relapse
social and cultural dimensions
- exposure is a prerequisite for use
- modelled by parents
- if parents are alcholics its more likely for kids to be
- abuse = moral weakness, failure of self control, sign of disease
- culture influences hw use/abuse is manifested,
- cultural expectations
treatment biological
- agonist substitution: safe drug with similar chemical composition
- antagonist treatment: blocks pleasurable effects
- aversive treatment: makes ingestion of substances unpleasant
- other meds to cope with withdrawal or reduce cravings
- efficacy: limited when used alone, better with psychological treatment
psychosocial treatment
- individual and group therapy = aversion therapy and covert sensitization - contingency management - community reinforcement - relapse prevention - community education to prevent - alcoholics anonymous - controlled use, harm reduction
gambling disorder
- recurrent problematic gambling that disrupts life
- gamble with increasing $ to achieve excitement’
- gamble more when money lost
- gambles when distressed
- jeopardizes relationships, jobs
- relies on others to provide$ to relieve financial situation
- lies to conceal involvemetn
- repeated attempts to control or stop
gambling disorder subtypes
- motivated by action
- motivated by escap e
gd onset and duration
- young adults and middle aged
- earlier onset associated with impulsivity and substance abuse
- for diagnosis 4+ symptoms in 12 months, impairment and distress
gd treatment
- less than 10% seek treatment
- cbt that targets gambling motivation showing promise