Chapter 11 Flashcards
two processes create new combinations of genetic info in populations during sexual reproduction
- indepenedent assortment of chromosomes
2. crossing over
independant assortment of chromosomes
produces gametes with different maternal and paternal chromosomes
the more chromosomes present, the greater the number of different gametes
crossing over
exchange of sections of chromosomes on homologous pairs
occurs during prophase 1 of meiosis
mixes maternal and paternal homologous chromosomes
mutations
change in the genetics of an organisms
point mutations
change in the nucleotide sequence or a small section of a nucleic acid. caused by:
-copying errors during DNA replication
-changes in the structure of nucleotides by:
high energy photons (radiation)
chemicals in the environment
types of point mutations
- base substitutions
2. base deletions
base substitutions
change in nucleotide sequence
base deletions
loss of nucleotide
results in a change in the amino acid sequences downstream from the deletion
chromosomal mutations
- extra or missing copies of chromosomes
results from nodisjunction (failure of chromosomes to seperate) during meiosis
missing chromsoems are lethal
extra chromosomes are usually lethal in animals
nondisjunction in meiosis 1
all abnormal gametes
results in extra chromosomes and missing chromosomes
nondisjunction in meiosis 2
normal and abnormal gametes
results in normal, extra, and missing chromosome
exceptions to lethal effects of extra chromosomes in animal
1. extra copies of sex chromosomes: extra X chromosomes are silenced Y chromosomes carry few geens XXX- normal female XYY- normal male XXY- sterile male 2. extra copy of chromosome 21 causes down syndrome
nondisjunction events
increase with age
chromosomal abnormalities: result from
from improper crossing over and seperation of chromosomes
a) deletions
b) duplications
c) inversions
d) translocation:
exchange of chromosomal material between non homologous chromosome
cane result in extra or missing regions of chromosome in gamates