Chapter 1: Structure and Functions of the Body Flashcards
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Describe the Macrostructure of Muscles
Large, Visiablestructures
Organs
Skeletal Muscles that contain muscle tissue, connective tissue, nerves, and blood vessels.
Describe Microstructures of Muscles
Connective Muscle Layers:
AKA Schematic of a muscle:
Epimysium ——(the outer layer)
Perimysium ——(surrounding each fasciculus/group of
fibers)
Endomysium—— (surrounding individual fibers)
Where does muscle growth occur on a cellular level?
Adds to Actin and Myosin
What is a sarcomere?
Functional contractile unit of muscle
Primarily made of Actin and myosin
Measured from z line to z line
What are Myofilaments?
Actin & Myosin
Actin
Thin filament
Molecules arranged in double helices
(like DNA)
Myosin
Thick Filament with the cross-bridge heads
pulls z-line toward center of sarcomere and shortening the muscle fiber
What are the 5 phases of the sliding filament theory?
- Resting phase
—Little Ca in Sarcoplasm
— Myosin heads detached
—Tripomyosin covers binding sites on actin - Excitation-Contraction coupling phase
—Ca released from action potential
— Ca binds to Troponin = conformational shift
— Troponin pulls tropomyosin away
— Myosin headds bind to actin - Contraction Phase
—Cocked heads
— Power storke (myosin fires and attches)
—ATP binds to myosin, making to release
— ATP hydrolyzed by ATPase and releases energy
— Back in the cocked position - Recharge Phase
—continues as long as there is Ca, ATP and ATPase - Relaxation phase
— Ca os sequestered, preventing heads from contracting
— CA is pumped (takes energy) back into SR
Motor end plate
The muscle fiber area is innervated by a motor neuron (axonal terminal)
—Muscle site of axonal terminal—
Acetylcholine
Neurotransmitters released by motor neuron NMJ
Action potential
All-or-None principle
Twitch
Summation
Motor Unit