Chapter 1 - ECM - Transport and Cell Membranes Flashcards
What are 3 ways of transporting substances across membrane?
Passive Diffusion
Transporters (Passive or active) = Conformational change
Channels (passive movement) = contineous pores
What are 3 factors that could infleunce rate of diffusion
Concentration
Size (smaller better)
Polarity (more hydrophobic better)
Name the 3 conformational change of a passive transporter
Outward
Occluded
Inward
What are the 3 conformational change for Active transport
Uniport
Symport
Antiport
What type of mutation does Cystic fibrosis come from?
Mutation in transport membrane
Which type of attachement do you see in cell-cell adhesions? Hint they tether to cytoskeletal filaments inside the cell
Anchoring jxn
Epithelia cells have this type of jxn that gaps btw cells
Occluding jxn
What type of jxn do you see in passwagewaylinks
Channel jxn
This type of jxn allows passageways for cell to cell across plasma membrane
Signal-relaying
In these cell-cell jxn, two types of cytoskeleton transmembrane families exist , what are they and what do they mediate
Cadherin - cell t cell
Integrin cell to matrix
How thick is the basal lamina
40-120nm thick
This type of fibrous proteins has oligosacch side chains
Glyco-proteins
This type of polysacch has GAG
Proteo-gylcans
what structure does a triplet glycine have?
Gly-proline-hydroxyproline
What structure does collagen have?
It has a triple L. helical strucutre
