Ch1-B Flashcards

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1
Q

what is not a cytoplasmic organelle

A

the nucleus

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2
Q

What type of interaction hold cell membranes together

A

non-covalent

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3
Q

How thick is the bilayer

A

5nm

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4
Q

What are the two types of phospholipids

A

Glycerides back bone and Sphingo back bone

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5
Q

Types of phosphoglycerides

A

Phosphatidyl-ethanolamine
Phosphatidyl-serine (-‘ve charge)
Phosphatidyl-choline

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6
Q

How is cholesterol oriented and where

A

In the bilayer, having the OH group close to polar head groups

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7
Q

What phospho/gylco lipid are on the cytosolic side

Which are on the extracell space

A

Extracell- choline - glycolipid and sphingomyelin

Cytosol : serine , ethanolamine mostly

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8
Q

in what are liposomes found to be effective

A

anti-cancer drugs

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9
Q

What links amino acids together

A

peptide bonds

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10
Q

Amyloidosis

A

insoluble aggregation of proteins in the 2ndary b-sheet pattern

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11
Q

Membran proteins : Amphiphilic alpha helix

A

Goes into the cytosol of the lipid bilayer originating at the hydrophobic face

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12
Q

Peripheral membrane proteins

A

attach to bilayer by noncovalent interactions or by Gpi-linker

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13
Q

What type crosses lipid bilayer in alphha helical confirmation?

A

Multi pass proteins:

amphiphilic alpha helix and peripheral membrane proteins

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14
Q

What type of membrane transporters does small molecule use

A

Multipass

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15
Q

What class of membrane proteins are cell-surface receptors

A

Transmembrane proteins

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16
Q

What does a transmembrane proteins get done to it

A

adding of an oligosacch

17
Q

Glycoproteins

A

covalent bond to oligosacch

18
Q

Proteo-glycans

A

attach a polysacch (GAG)

19
Q

what is the name of the carbohydrate layer on the surface?

A

Glycocalyx

20
Q

what ways does movement occur in the membrane?

A

Rotational or laterla difusion

21
Q

what 4ways does mobility of plasma membrane occur -TIA

A

Tethered outside or inside(cytosol) the cell
Interact on surface
aggregation of proteins

22
Q

glycolipids function as

A

membrane protection
cell-cell recognition
membrane elect property if charged

23
Q

Membrane proteins

A

are amphiphilic

24
Q

calnexin and calreticulin

A

prevent aggregation by being chaperones and not letting them proteins fold