Ch1-B Flashcards
what is not a cytoplasmic organelle
the nucleus
What type of interaction hold cell membranes together
non-covalent
How thick is the bilayer
5nm
What are the two types of phospholipids
Glycerides back bone and Sphingo back bone
Types of phosphoglycerides
Phosphatidyl-ethanolamine
Phosphatidyl-serine (-‘ve charge)
Phosphatidyl-choline
How is cholesterol oriented and where
In the bilayer, having the OH group close to polar head groups
What phospho/gylco lipid are on the cytosolic side
Which are on the extracell space
Extracell- choline - glycolipid and sphingomyelin
Cytosol : serine , ethanolamine mostly
in what are liposomes found to be effective
anti-cancer drugs
What links amino acids together
peptide bonds
Amyloidosis
insoluble aggregation of proteins in the 2ndary b-sheet pattern
Membran proteins : Amphiphilic alpha helix
Goes into the cytosol of the lipid bilayer originating at the hydrophobic face
Peripheral membrane proteins
attach to bilayer by noncovalent interactions or by Gpi-linker
What type crosses lipid bilayer in alphha helical confirmation?
Multi pass proteins:
amphiphilic alpha helix and peripheral membrane proteins
What type of membrane transporters does small molecule use
Multipass
What class of membrane proteins are cell-surface receptors
Transmembrane proteins
What does a transmembrane proteins get done to it
adding of an oligosacch
Glycoproteins
covalent bond to oligosacch
Proteo-glycans
attach a polysacch (GAG)
what is the name of the carbohydrate layer on the surface?
Glycocalyx
what ways does movement occur in the membrane?
Rotational or laterla difusion
what 4ways does mobility of plasma membrane occur -TIA
Tethered outside or inside(cytosol) the cell
Interact on surface
aggregation of proteins
glycolipids function as
membrane protection
cell-cell recognition
membrane elect property if charged
Membrane proteins
are amphiphilic
calnexin and calreticulin
prevent aggregation by being chaperones and not letting them proteins fold
