Ch1-B Flashcards
what is not a cytoplasmic organelle
the nucleus
What type of interaction hold cell membranes together
non-covalent
How thick is the bilayer
5nm
What are the two types of phospholipids
Glycerides back bone and Sphingo back bone
Types of phosphoglycerides
Phosphatidyl-ethanolamine
Phosphatidyl-serine (-‘ve charge)
Phosphatidyl-choline
How is cholesterol oriented and where
In the bilayer, having the OH group close to polar head groups
What phospho/gylco lipid are on the cytosolic side
Which are on the extracell space
Extracell- choline - glycolipid and sphingomyelin
Cytosol : serine , ethanolamine mostly
in what are liposomes found to be effective
anti-cancer drugs
What links amino acids together
peptide bonds
Amyloidosis
insoluble aggregation of proteins in the 2ndary b-sheet pattern
Membran proteins : Amphiphilic alpha helix
Goes into the cytosol of the lipid bilayer originating at the hydrophobic face
Peripheral membrane proteins
attach to bilayer by noncovalent interactions or by Gpi-linker
What type crosses lipid bilayer in alphha helical confirmation?
Multi pass proteins:
amphiphilic alpha helix and peripheral membrane proteins
What type of membrane transporters does small molecule use
Multipass
What class of membrane proteins are cell-surface receptors
Transmembrane proteins