Chapter 1 Flashcards

1
Q

Which is the best definition of “immunity”?

A

The state of being resistant to reinfection with a pathogen

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2
Q

What happens to a pathogen as it becomes attenuated?

A

It has weakened virulence.

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3
Q

Which of the following is the BEST example of herd immunity?

A

A child infected with measles travels from Germany to the United States. Several babies contract the disease, but the outbreak is largely contained due to vaccinations.

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4
Q

Which of the following diseases does NOT currently have an effective vaccine?

A

HIV

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5
Q

Effectors of the humoral immune system are known as:

A

All of the above

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6
Q

Which of the following cell types are lymphocytes?

A

T cells

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7
Q

Which of the following is TRUE about antigens?

A

They are recognized by T cells or B cells.

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8
Q

Which of the following is a fungal pathogen?

A

Candida albicans

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9
Q

Which of the following cell types is MOST commonly associated with recognizing antigens found inside of cells?

A

CTL

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10
Q

Which of the following classes of cell surface receptors are directly encoded in the germline?

A

PRR

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11
Q

What is the central mechanism for establishing self-tolerance?

A

Self-reactive T cells and B cells are killed during development.

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12
Q

Which of the following BEST describes chemokines?

A

Soluble proteins that recruit specific cells to an area

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13
Q

Which of the following statements BEST differentiates innate and adaptive immune responses?

A

Innate responses are stronger during the primary and less important during the secondary response, while adaptive responses are less robust during primary responses and stronger during secondary responses.

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14
Q

How do memory cells develop?

A

T cells and B cells from the primary response persist and become reactivated.

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15
Q

Which of the following is the BEST example of a hypersensitivity reaction?

A

Inflammation of the airways in response to pollen

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16
Q

HIV disease is a/an:

A

immunodeficiency.

17
Q

Predict the outcome of being immunosuppressed as it relates to the development of cancer.

A

Immunosuppressed individuals are at higher risk of cancer because the immune system recognizes and destroys cancerous cells.

18
Q

What occurs when someone receives a tissue transplant from an unrelated individual?

A

The host’s lymphocytes enter the tissues and become activated.

19
Q

Conditions in which the immune system attacks self-antigens are known as:

A

autoimmunity.