CHAPTER 09: LOWER LIMB Flashcards

1
Q

What are the contents of the anterior compartment of the leg?

A

Muscles - EHL, EDL, Tib Ant, Peron Tertius,
Nerve → Deep peroneal
Artery→ Ant tibial
Main function→ Dorsiflexion

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2
Q

What are the contents of the lateral compartment of the leg?

A

Muscles - Peroneus Longus, Peroneus Brevis
Nerve → Superficial peroneal
Artery → peroneal
Function→ eversion

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3
Q

What are the contents of the posterior compartment of the leg?

A
Muscles - Deep → FHL, FDL, Tib Post
Muscles - Superficial → Gastrocnemius, Soleus, Plantaris
Nerve → Tibial
Artery → Post tibial
Main function→ plantar flexion
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4
Q

What is the nerve supply to the lower leg?

A
Posterior thigh = post fem cut n
Lateral thigh = lat fem cut n
Anterior thigh = int & med fem cut n
Medial upper thigh = cut br of obturator n
Lateral calf = sural n
Medial calf = saphenous n
Dorsum of foot = superficial peroneal n
1st web = deep peroneal n
Sole of foot = medial and lateral plantar ns from post tib
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5
Q

What is the Gustilo and Anderson classification?

A

Gustilo & Anderson (1976) 1025 patients

Grade I - clean puncture, 1cm, no traumatic flaps, no extensive soft tissue damage, or avulsions, simple#
Grade III - Extensive soft tissue inc skin, muscle and neurovascular, high energy, severe crush, comminuted #, segmental #, bone loss, GSW, traumatic amputation.

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6
Q

Grade 2

A

Grade II - >1cm, no traumatic flaps, no extensive soft tissue damage, or avulsions, simple#

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7
Q

How was it modified?

A

Gustilo & Mendoza (1984) subdivided grade III:
Grade IIIa = high energy regardless of wound size, adequate soft tissue – rare, often posterior wounds
Grade IIIb = Extensive soft tissue with periosteal stripping and bone exposure, major wound contamination, bone loss – most common – half get infected
Grade IIIc = arterial injury requiring repair

Criticism - most injuries lumped into IIIb

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8
Q

Name another classification for lower limb trauma

A

Byrd and Spicer
Type I – Low Energy
o spiral or oblique fracture,
o with skin laceration less than 2cm,
o clean wound
Type II – Moderate Energy
o comminuted or displaced fracture,
o skin laceration more than 2cm,
o moderate adjacent skin and muscle contusion,
o without devitalised soft tissue
Type III – High Energy
o significantly displaced / severe comminution / segmental fracture, or
o bone defect with extensive associated skin loss and devitalised muscle
o Type IIIa – Extreme Energy
o As in III, but
o with extreme forces such as in gunshot, crush, degloving or
o associated vascular injury needing repair
Criticism - high inter-observer variability

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9
Q

What is the Mangled Extremity Severity Score?

A
MESS = Mangled extremity severity score - Seattle Trauma Centre - Is limb salvageable?
Score/22
If >7/22 = 100% amputation
4 variables SAVE (shock, age, vasc, energy)
o Energy → Low =1, Medium = 2, High = 3, Very High = 4
o Ischaemia (double over 6hrs) ↓pulse normal perfusion = 1, no pulse, paraesthesia ↓cap refill = 2, Cool paralysed insensate or numb = 3.
o Shock → Systolic BP always ↑90 = 1, transient ↓BP = 2, Persistent ↓BP = 3
o Age → <30yrs = 1, 30-50yrs =2, over 50 yrs = 3
Criticism - Did not mention sensate vs insensate, salvageable ones have to fit into 0-7- once again, lumped together, how relevant are parameters?
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10
Q

Who classified degloving injuries of the lower limb?

A

Arnez and Tyler. (BJPS 1999)
I - IV based on energy transfer and circumferential vs non-circumferential
Type 1 → non-circumferential degloving
Type 2 → abrasion but no degloving
Type 3 → circumferential degloving
Type 4 → circumferential degloving with avulsion between deep tissue planes (IM, Muscle - periosteum)
Types 3 & 4 paradoxically need serial conservative debridements and delayed recon. Early radical debridement → functionless limb.

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11
Q

What other classifications are there for lower limb trauma?

A

Limb Salvage Index - 7 components (injury to an artery, deep vein, nerve, bone, skin, muscle & warm ischaemia time. Criticism - predictive results have not been reproduced.
Hanover Fracture Scale-13 weighted variables
AO, Hidalgo, Harold Ellis JBJS 1958

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12
Q

What is the most commonly quoted document for lower limb management?

A

Lower Limb Trauma Standards

Joint BOA / BAPRAS

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13
Q

Who should be referred to specialist centres?

A
tib+fib, 
comminuted, 
segmental, bone loss
skin loss, 
degloving, 
devitalised muscle, 
damaged artery
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14
Q

What are the recommended antibiotic regime?

A
  1. Start Abx asap, within 3hrs
    - Augmentin / cefuroxime (or clindamycin)
  2. At 1st debridement (until (3) or 72hrs)
    - Augmentin + gentamicin (1.5mg/kg)
  3. At skeletal stabilisation & definitive closure
    - Gent + vancomycin / teicoplanin
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15
Q

What is the recommended time for debridement?

What is the recommended time for achieving wound closure?

A

Immediate exploration only if

  1. gross contamination (agricultural, marine, sewage)
  2. compartment syndrome
  3. devascularised limb
  4. multiply injured patient

Definitive wound closure - within 1wk

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16
Q

What are the indications for amputation?

A
  1. damage control
  2. warm ischaemia time >6hrs
    3 incomplete traumatic amputation, severe damage to distal remnant

Amputation considered if

  1. avascular limb >4hrs
  2. segmental muscle loss >2compartments
  3. segmental bone loss >1/3 tibia

reduced plantar sensation is not an indication

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17
Q

What should the A&E do before referral?

A

Initial assessment & Rx according to ATLS
Haemorrhage control - direct pressure
Limb assessment - document & repeated after manipulation
Wound - remove gross contaminants, photo, dress
Antibiotics, anti-tetanus
X ray 2 views tibia & ankle

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18
Q

What are the different types of fixation?

A

Spanning external fixator (quad frame)
Internal fixation - only if definitive closure can be performed at the same time
- intramedullary nailing - reamed / unreamed avoids disruption of endosteal blood supply
- plating, exacerbates periosteal stripping and infection risk
Multiplanar and circular fixators (Ilizarov, Taylors spacial frame with computer program)
Avoid nails in children (disrupt growth plates)

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19
Q

What evidence is there for muscle vs fasciocutaneous flaps in lower limb?

A

diaphyseal tib fractures w periosteal stripping -muscle flaps better
metaphyseal fractures esp ankle - FC flaps best (free / local)

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20
Q

How is compartment syndrome diagnosed?

A
  • Pain on palp.
  • Pain on passive stretch (Homans’ sign)
  • Swelling/turgor
  • Sensory deficit (1st Webspace)
  • Muscle weakness
  • 6% of Gustillo IIIB
  • Loss of pulses = too late

Intra-compartment pressure = diastolic BP - compartment pressure
Decompress if
- Compartment pressure >30mmHg, or
- <30mmHg below diastolic pressure.

  • Measure using Whiteside’s Infusion technique (3-way tap/syringe etc) or Stryker STIC device.
  • Rest 5mmHg, Exercised 20 - 30mmHg, within 30 of diastolic
  • Danger if delta-P 10-30
  • Most imp measure in anterior comp at fracture level
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21
Q

In compartment syndrome, what is the injury sequence?

A
  1. Nerve
  2. Muscle (deep ones first)
  3. Arteries
  4. Veins
  5. Skin

Upper limb

  • FDP FPL and Median n. first affected - i.e deep structures
  • Ellipsoid necrosis
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22
Q

Where are the fasciotomy incisions situated?

A

Anterolateral incision
2 cm lateral to sc tibial border
divide lateral intermuscular septum to enter peroneal compartment
releases anterior and lateral compartments

Posteromedial incision
1cm medial to sc tibial border
at ankle, identify fascia over post tibial NV bundle, split fascia upwards detaching soleus from tibia
releases superficial and deep post comps

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23
Q

Principles of Rx - Vascular injuries of lower limb

A

compare with normal leg - if compromised explore without delay (<4hrs)
pulse present does not equal intact artery- angiography may influence surgery
shunting will reduce ischaemia time, reduce fracture then revasc w reversed vein grafts
1 single patent vessel is not contraindication to free flap recon w end to side anastomosis, but aim to repair injured vessels

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24
Q

How do you deal with degloved plantar skin?

A

a. If suprafascial, is defatted and replaced as full-thickness graft
b. If subfascial and proximally based, is sutured back without tension
c. If subfascial and distally based, is considered for revascularisation

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25
What outcome measures are useful for lower limb trauma pts?
Pt health status questionnaires Enneking Score (compares with contralateral uninjured limb) Union time of fracture
26
What is the surgical plan for lower limb trauma?
1. Debridement of all non-viable tissue, excise wound. Lavage 6L 2. Fasciotomy → crush / reperfusion 3. Restore perfusion by arterial repair (temp shunts if needed while bone fixed) 4. Reduce and stabilise fracture 5. Soft tissue cover
27
What are the timings and advantages of early cover of open fracture?
``` Advantages of early or emergency cover of the open fracture o Less infection o Fewer operations o Shorter hospital time o Earlier mobilisation o Lower treatment costs ``` Emergency free flap → at the time of first debridement < 24hrs Early – 24-72hrs Delayed 72hrs – 3mths Late > 3 months
28
What are the options for soft tissue cover?
Depends on defect, pt, surgeon Secondary intention - VAC, Papineau technique (drill holes, moist) Primary closure: Gustillo I+II SSG: Gustillo IIIA FC flap prox / distally based ( distal = PT perforators) 5 or 10cm above medial malleolus, intermuscular septum b/t FHL & soleus Cross leg flap - immobilisation main problem Free flap - Gustillo IIIB
29
What are the recipient vessels for free flaps?
1. Post Tibial → usu well protected, best option (end to side) 2. Ant Tib A → usu compromised by trauma 3. Geniculate vessels in pop fossa 4. Vein grafts to the femoral canal → proximal vein graft first before detaching the flap, leave the vein graft as a loop then divide and anastomose to the donor vessels.
30
What local / pedicled flap options are there for lower leg recon?
``` Upper 1/3 - proximally based FC (peroneal / post tib a) - gastrocnemius Middle 1/3 - prox / distally based FC - soleus - bipedicled tibialis ant turnover flap Lower 1/3 - distally based FC - adipofascial turnover flap - sural artery flap (based on A&V of sural nerve: small & unreliable, sacrifice nerve) ```
31
What local / pedicled flap options are there for ankle / heel recon?
Ankle / heel - distally based islanded FC flap - medial plantar island flap (can be sensate, based on medial plantar artery) - dorsalis pedis flap
32
What paper do you know about definitive cover for lower limb?
Early microsurgical reconstruction of complex trauma of the extremities (GODINA 1986 PRS)  Early 3 months (to 12yrs) – 9.5% failure, longest hospital stay, slowest to heal, most anaesthetics o 26% of 1st 100 free flaps failed, 4% of last o But  Injuries not described – old ladies with pre-tib lacerations were lumped in with severest injuries.  Infections not described  62/532 cases in Kuwait  Return to weight bearing not mentioned  Published posthumously
32
Early, late and delayed wound closure
Early <72hrs – 0.75% failure, lowest infection (even lower under free flaps), quickest bone healing, shortest hospital stay, fewest anaesthetics, fewest free flap failures Late 72hrs – 3 months – 12% failure, highest infection Delayed >3 months (to 12yrs) – 9.5% failure, longest hospital stay, slowest to heal, most anaesthetics o 26% of 1st 100 free flaps failed, 4% of last
33
What did Gopal's paper in 2000 show about fix & flap?
debride, ORIF & flap within 72hrs (33/80) - flap failure rate 3.5% - deep infection rate 9.5% - bone union 39wks - retrospective study, no functional outcome assessment
34
How are bone defects managed?
1. Primary bone shortening o Segmental defects < 5cm (>5cm → kinking of vessels & ischaemia) 2. Temporary Spacer - Masquelet technique o Gentamicin-impregnated methylmethacrylate spacers bridge bony defect and keep limb length. Later removed and defect reconstructed 3. Bone Grafting o Small defect + well vascularised bed o Delayed cancellous bone grafting usually performed about 6 – 12 weeks after the injury when soft tissues are healed 4. Ilizarov Techniques o 5-8cm bone gaps 5. Vascularised bone o >8cm bone gaps
35
How do you reconstruct bone defects with Ilizarov technique?
4. Ilizarov Techniques o 5-8cm bone gaps o Limb SHORTENING followed by DISTRACTION OSTEOGENESIS o Limb HELD TO LENGTH followed by BONE TRANSPORT → corticotomy to develop the mobile segment (preserving medullary and periosteal supply), Need adequate soft tissue/ free flap, avoids soft tissue contracture of shortened limb (muscle atrophy, joint contractures, stiffness, disuse osteoporosis) o Latent period ~ 5 days then 1mm/day o Bone must be healthy o Monitor distraction by serial x-rays → avoid too slow = premature fusion or too fast = lucency o When at required length, leave frame for 2 months → consolidate o Complications → length discrepancy, refracture, pin infections, incomplete docking/non-union (req 2ry bone graft).
36
How do you reconstruct bone defects with vascularised bone graft?
5. Reconstruction with vascularised bone o Complex reconstruction performed in early post trauma phase o Vascularised bone good for segmental defects > 8cm o Free fibula or DCIA o Bone and soft tissue free flap together usually required. o Takes a long time to hypertrophy and strengthen → strict non wt bearing or will #.
37
How is chronic osteomyelitis managed?
Incidence - 4.5% in Gustillo III ``` Investigations o X-rays o Bone scan o Wound swab/culture o Arteriography ``` Treatment o Radical wound debridement → soft tissue and sequestrum o Bone graft to defect → free or vascularised o Rigid immobilisation o Free muscle flap → brings good blood o Antibiotics → local delivery systems / systemic 2-6/52
38
What are the causes of leg ulcers?
VATIMAN Venous disease (85%) Arterial disease Trauma → insect bites, trophic ulcers, DSH, Frostbite, Radiation Infection → bacterial, fungal, TB, syphilis Metabolic→ Diabetes, Necrobiosis lipoidica diabeticorum, pyoderma gangrenosum, porphyria, gout Autoimmune→ Lupus, RhA, Polyarteritis Nodosa Neoplasia → SCC (Marjolin’s Ulcer), BCC, Kaposi’s sarcoma, lymphoma
39
What causes venous ulceration?
- varicose veins, DVT, chronic venous insufficiency, poor calf muscle func, AV fistulae, obesity, prev leg fracture thrombophlebitis -> valve incompetence Lipodermatosclerosis = scarred, fibrotic hyperpigmented skin 2dry to venous hyperten
40
What is important in history of leg ulcers?
Time (Marjolins), how it started ? trauma Previous trauma, mobility, check footwear Claudication? Conditions predisposing to poor wound healing - diabetes, inflammatory disease, smoking?
41
Examination of leg ulcers
Ulcer → characteristics, shape, size edge etc, signs of malignancy Circulation → Temp of leg, cap refill, pulses, Buergers angle Sensation→ presence and pattern, glove and stocking - ?diabetes.
42
Investigations for leg ulcers
Wound swab for micro Measure ABPI normally 1.2, ↓ in arterial disease Vascular studies → venous duplex for clots, angio for ischaemia Radiology → X-ray and bone scans for bony involvement Biopsy → exclude malignancy
43
Management of leg ulcers
Non – op o Elevation, meticulous hygiene, elastic compression Op o failed conservative, if ↑↑↑ pain o Rx → subfascial ligation of the perforating vessels o SSG → high recurrence rate if not Rx cause o Local or free flaps → very rarely indicated
44
How do you prepare a patient for compression bandaging? What does it involve?
``` Limb assessment including ABPI (less than 0.8 not indicated) Wound assessment, size and photograph Dressings Pain assessment Pt understanding and commitment ``` ``` 4 layer bandaging Orthopaedic wool Cotton crepe Elastic extensible bandaging 17mmHg Cohesive bandage 23mmHg ```
45
What is the pathophysiology of diabetic foot ulcers?
1. Sensory neuropathy → loss of protective sensation 2. Motor neuropathy → derangement of joints → pressure sores over metatarsal heads 3. Autonomic neuropathy → dry, cracked skin → infection 4. Peripheral vascular disease → tissue hypoxia → infection 5. ↓ cellular and humeral immunity → infection
46
How do you manage diabetic foot ulcers?
Prevention & Non-surgical 1. Effective gylcaemic control 2. Chiropody, DM foot care regimes, shoes 3. Systemic antibiotics 4. Hyperbaric Oxygen
47
What are the surgical options?
``` Surgical 1. Wound debridement 2. Revascularisation 3. Amputation / arthrodesis Amputation at level of - toes - TMT joints → Lisfranc - talonavicular joint → Chopart - just above ankle → Syme’s - MTP joint arthrodesis for dorsal ulceration as a result of motor imbalance Soft tissue - dressings, granulation, SSG - local flap - medial plantar, distally based FC - free flap ```
48
Lower limb amputations
1. Hindquarter 2. Transfemoral - must do adductor magnus myodesis and myoplasty of flexors to extensors, 11-13cm 3. Knee disarticulation (better in kids) 4. Transtibial - 10 - 14cm – ant/post tib nerves and peroneal nerves divided. Smooth, bevelled end to tibia, fib cut 1cm shorter. Myoplasty (stitch muscle ends together vs myodesis - drill into bone) usually enough. - Burgess - Long post flap - Robinson - Skew flap - Sagittal Flap - End myodesis important says Umraz 5. Symes Osteointegration
49
What is lymphoedema?
Abnormal collection of protein-rich interstitial fluid in subcutaneous tissues. May be caused by a maldevelopment of the lymphatics or an acquired obstruction. Lymphoedema is confined to subcut tissues and skin
50
What is the anatomy of the lymphatic system?
Embryonically develops from venous system Superficial (follows veins) and deep lymphatic vessels (follows arteries in deep fascia). None in muscles. Superficial joins deep system at cubital fossa, popliteal fossa & inguinal region Lower limb → Cisterna chyli (thin walled sac at L1-2) → thoracic duct at T12 → int jug vein and left subclavian vein at their confluence. Can be damaged in Level IV LND Lymph from right arm → right subclavian trunk Right side of head → into right jugular lymph trunk.
51
What is the pathophysiology of lymphoedema?
Abnormal flow / obstruction → stasis → valvular mechanism disrupted → interstitial fluid cannot return to vasc system → raised oncotic pressure in tissues → oedema Protein triggers inflammatory response → collagen deposition and fibroplasia → stasis predisposes to infection, oedema reduces oxygen transport to cells → hypoxia → more inflammation
52
What is the function of the lymphatic system?
1. Returns protein and lipid from interstitial space to vascular system 2. 50% of body's albumin processed each 24hrs 3. Humoral immune system → Carries foreign particles or proteins to LNs 4. Fat transport pathway from GI tract to vascular system.
53
How do you classify lymphoedema?
``` Primary vs Secondary Primary 1. Lymphoedema Congenita 15-20%, FHx Milroy's disease (sex linked) usu anaplastic 2. Lymphoedema praecox (puberty) 70-80% primary cases usu hypoplastic 3. Lymphoedema tarda (after 35) 10% Meige disease usu hyperplastic ```
54
What are the secondary causes of lymphoedema?
Mechanical obstruction of a normal lymphatic system. o Invasion by Tumour →1ry or 2ry o Infection → Filariasis from Wuchereria bancrofti (elephantiasis of legs and genitalia, commonest lymphoedema in world), TB, lymphogranuloma and recurrent infection. o Inflammation → snake bites, insect bites o Irradiation o Iatrogenic → ELND, v vein stripping
55
What is important in history and examination?
onset, inciting factors, symptoms, prev Rx skin - thick brawny, fissures, ulceration neurovascular status
56
What are the differential diagnoses?
``` Lipodystrophy, Myxoedema and Oedema Venous thrombosis, Venous stasis, Klippel-Trenaunay syndrome, Congestive heart failure, Low protein state, Factitious use of tourniquets ```
57
What malignant changes may occur?
Lymphangiosarcoma in 10% of severe cases after 10yrs. | Stewart-Treves syndrome → malignant change in postmastectomy lymphoedema → high mortality
58
What imaging may be used?
``` Doppler USS (venous obstruction) CT scan, MRI, lymphoscinitigraphy ```
59
How is treatment classified? What excisional treatments are available?
Non-surgical (90%) - elevation, compression, exercise, meticulous hygiene, treat inf, lose weight - NO diuretics - Complex decongestive physiotherapy Surgical 10% (Excisional & Physiological) Excisional Charles technique - resurfacing - Circumferential excision of lymphoedematous tissue + SSG to fascia Homans technique - debulking - Longitudinal segment of skin and subcut tissue removed. Edges sewn together. Medially then laterally later. Thompson technique -Segment of s/c tissue excised. Dermal flap tunnelled through fascia into muscular compartment Liposuction - may worsen fibrosis
60
What physiological treatments are there?
Lymphangioplasty ``` Omental transfer (pedicled → affected limb) Enteromesenteric flap (transected iliac / inguinal nodes covered w segment of ilium) ``` Lymphovenous shunts (Koshima 2000 J Recon Micro) Lympholymphatic anastomosis Free vascularised LN transfers (Becker 2000)
61
Name the layers in the sole of the foot
Layer 1 = Abductor Hall, Flex Dig Brevis, Abductor Dig Minimi Layer 2 = FHL, FDL, Lumbricals, Flexor accessorius Layer 3 = FHB, Add Hall, Flex Dig Min Brevis Layer 4 = Interosseii
62
What are the risks of chronic lymphoedema?
- Recurrent cellulitis → 30% of cases of primary and assoc with ↑ disease - Ulceration - Verrucous skin changes - ↑ risk if SCC - Lymphangiosarcoma → Rare less than 1 % but has poor prognosis - Kaposi’s sarcoma → rare but reported
63
Causes of foot defects
Vascular - arterial or venous Metabolic - diabetes (microangiopathy, neuropathy), alcoholism, gout Tumour - melanoma, epithelioma, sarcoma of bone, soft tissue Infection Trauma Malformation (club foot)
64
What considerations are taken into account when reconstructing large foot defects?
Can and should this foot be saved? | How can the best functional and morphologic recovery be achieved?
65
How are foot defects classified?
Size - Small tissue defects less than 3 cm2 - Large tissue defects greater than 3 cm2 Depth - Skin - Subcutaneous and aponeurosis systems - Muscle - Bone - skin, subcutaneous fat, plantar fascia, muscles, bone Localization - Anatomic areas (dorsum, medial, lateral side, sole, heel, toes) - Baropodometric areas (WB or non-weightbearing [NWB])
66
What are the indications for surgical treatment?
Skin graft or local flap is indicated 1. < 3cm2 limited - traumatic or neoplastic 2. Small (< 3 cm2) involving aponeurosis or muscular layers or even more superficial but resistant to medical therapy 3. Limited* > 3 cm2 of NWB areas Free flap is indicated 1. > 3 cm2 of WB areas 2. Bone loss of WB areas *Limited = skin & sub cut tissue only
67
What are the indications for medical treatment?
<3cm skin and sc defects of vascular, metabolic and infective aetiology
68
What is the arterial supply to the foot?
``` Ant tib → dorsalis pedis Post tib → medial and lateral plantar arteries Peroneal → branches to posterior ankle and calcaneum ```
69
What is the innervation to the foot?
Anterior tibial nerve → EDB, EHB → skin in 1st WS Posterior tibial nerve → Medial plantar nerve → abductor hallucis, flexor brevis digitorum, flexor brevis hallucis, and the first and second lumbricales → sole, 1st - 1/2 of 4th toe Lateral plantar nerve → flexor brevis minimi digiti, all interosseus muscles, lumbricales, adductor obliquus hallucis, adductor transversus hallucis, abductor minimi digiti, and accessorius → 1/2 of 4th & 5th toe Saphenous nerve → medial foot
70
What is your treatment algorithm?
< 3 cm2 Soft tissue WB areas Local flap < 3 cm2 Soft tissue NWB areas Skin grafts >3 cm2 Soft tissue WB areas Free flap (free FC, MC, muscle flap + graft) >3 cm2 Soft tissue and bone loss WB areas Free osteocutaneous flap
71
Choice of local flap from the sole of the foot?
Sole 1. MEDIAL PLANTAR FLAP (O'Brien and Shanahan, 1979) Type B fasciocutaneous flap Maximum dimensions - 10 X 7 cm Pedicle - Medial plantar artery 12cm long, proximally or distally based Arc of rotation - calcaneum, medial malleolar area, distal WB areas on heads of metatarsus 2. Transposition, rotation, and V-Y skin flaps Sensitive fasciocutaneous or cutaneous flaps to cover WB areas Defects less than 3 cm2, with random vascularisation 3. Island flaps of toes based on digital artery (WB areas of MT heads) - difficult dissection ``` 4. Flexor brevis digitorum Abductor brevis hallucis Abductor brevis minimi Flexor brevis hallucis ```
72
Choice of flaps from the dorsum of the foot?
1. Dorsalis pedis flap Type B fasciocutaneous flap Sensate FC or MC flap (including the extensor brevis digitorum muscle) Flap - dorsal skin of the medial two thirds of the foot from ankle to toes Pedicle - septocutaneous perforators of dorsalis pedis and first dorsal metatarsal arteries, 6-10cm long, 2-3mm diameter Arc of rotation - Medial or lateral dorsal area, malleolar areas 2. First webspace flap Fasciocutaneous sensitive flap harvested from the first web space Very small dimensions Pedicle - First web space artery, which is the terminal branch of the dorsalis pedis artery Arc of rotation - Distal dorsum
73
What choices of flaps are there from the lateral and medial aspects of the foot?
1. Lateral calcaneal flap Cutaneous sensate flap below lateral malleolar area along lateral side of foot Pedicle - Lateral calcaneal artery, (terminal branch of the peroneal artery) Innervation - branches from sural nerve Arc of rotation - Achilles tendon and lateral malleolar area 2. Medial pedis flap
74
What regional / island flaps are available for foot reconstruction?
1. Sural artery flap (Donski 1983) Type A fasciocutaneous flap Pedicle - Sural artery, branch of the peroneal artery Flap - b/t popliteal fossa and midposterior leg b/t medial and lateral heads of gastrocnemius. The flap can measure 15 x 6 cm and may include the sural nerve as a neurosensory flap. Arc of rotation - Achilles tendon and lateral malleolar area 2. Perforator flap from posterior tibialis artery Type B fasciocutaneous flap Flap - medial aspect of leg along axis from knee to medial malleolus b/t soleus and flexor longus digitorum Pedicle - Septocutaneous branches from the posterior tibialis artery Arc of rotation - Medial malleolar area, calcaneum, proximal dorsum of foot 3. Reverse dermis or fascia flap Dermal or adipofascial flap harvested from posterior leg, +/- donor skin grafted Pedicle - Random Arc of rotation - Calcaneum, Achilles tendon
75
What free flaps for the foot are suitable for reconstruction?
Cutaneous 1. Groin flap (Daniel and Taylor, 1973) Pedicle - Superficial iliac circumflex artery 2. Scapular Pedicle - Circumflex artery of the scapula 3. Parascapular Pedicle - Descending branch of the circumflex artery of the scapula ``` Fasciocutaneous 1. Radial (Chang, 1978) 2. Lateral arm Pedicle - Septocutaneous branches from the brachialis profunda artery 3. Dorsalis pedis ``` ``` Muscular 1. LD (thoracodorsal) 2. Gracilis (Tamai 1971) Pedicle - 3. Anterior serratus Pedicle - Branch from thoracodorsal artery ``` ``` Osteocutaneous Iliac crest Pedicle - For the bone, profundus iliac circumflex artery; for the skin paddle, superficial iliac circumflex artery Fibula - peroneal artery ```
76
What is the epidemiology of sarcoma?
- Sarcomas = 1% of all malignant disease - 50% of deep sarcomas are lower limb, most in thigh - 1250/yr in UK
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How are sarcomas classified?
By: - Tissue of origin - TNMG classification: Stage - Enneking classification (out of date)
78
How are sarcomas classified by their tissue of origin?
- Smooth muscle → leiomyosarcoma – if truly dermal - good prognosis, don't metastasise, if subcut - metastasise - Striated muscle → rhabdomyosarcoma - Fat → Liposarcoma - Blood Vessels → angiosarcoma and Kaposi sarcoma - Lymph channels → lymphangiosarcoma - Fibrous tissue → Fibrosarcoma - Nerve → malignant schwannoma - Synovial tissue → synovial sarcoma - Skin → dermatofibrosarcoma protuberans (DFSP), atypical fibroxanthoma (AFX), and malignant fibrous histiocytoma (MFH)
79
What is the TNMG classification?
TNMG – AJCC ’92, ‘97 - T1 (5cm) - T3 (invasion of bone, vascularity or nerve) - N0 or N1(histologically confirmed) - M0 or M1 (distant mets) - G1 low grade tumour - G2 intermediate - G3 high grade Stage 1 - T1 or T2, G1 Stage 2 - T1 or T2 , G2 Stage 3 - T1 or T2, N1, G3 Stage 4 - T3 M1
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T classification of sarcoma
T1 (<5cm), T2 (>5cm), T3 (invasion of bone, vascularity, or nerve)
81
What are the principles of sarcoma treatment?
- Primary amputation rare - no survival benefit - Isolated limb perfusion - Melphalan (cytotoxic) and TNF-alpha (biological) - Wide skin margins usually illogical - usually margins are defined by a neurovascular structure - e.g. sciatic nerve ``` Sarcoma Reconstruction – same principles as for Head & neck  MDT lead  Hole filling in 10%  Know your role as a Plastic Surgeon  Timing – Radiotherapy ```
82
How do sarcomas present?
- Slowly enlarging mass - May also produce pressure on surrounding structures - Systemic symptoms e.g. ↓wt, malaise and rigors ``` Presenting features of 526 pts with soft tissue sarcomas (Johnson Ann RCS Eng 2001) 1. Subcutaneous mass >5cm 2. Pain 3. Increase in size 4. Depth beneath deep fascia ```
83
What investigations are necessary?
``` ASSESS EXTENT OF LESION 1. X-rays 2. MRI → Gadolinium aides resolution 3. CT → assess bony involvement 4. Angiography → if vessel involvement suspected 5. Radionuclide imaging → 3 phases A. Arterial phase → inflow into tumour B. Venous phase → venous pooling within tumour C. Osseous phase → bony invasion ``` HISTOLOGY - Biopsy → Must be done CORRECTLY - POOR BIOPSY TECHNIQUE = WORSE PROGNOSIS, therefore: 1. Only AFTER radiology complete 2. FNA or Trucut 3. Skin entry must be removed by excision 4. Incision biopsy NOT recommended 5. Should be performed in the unit where definitive surgery is planned (SAME SURGEON)
84
What are the principles of biopsy?
1. Plan biopsy site so that it will be excised subsequently 2. Avoid transverse incisions 3. Same surgeon performing biopsy and subsequent excision 4. Avoid contamination of adjacent structures 5. Good tissue handling 6. Consider referral before biopsying
85
What is the surgical management?
 Large deep sarcomata should be managed in specialised units  Deeply situated sarcomas are surrounded by pseoudocapsule.  Enucleation → prohibitively high recurrence rates  Ideally resect with one uninvolved anatomical plane in each direction.  Functional compartmentectomy (preserving at least one muscle within compartment) performed whenever possible  Resection should include both origin and insertion of the muscle in which the tumour occurs. If not possible then at least 10cm of muscle on either side of tumour.  preserve major nerve in compartment unless directly infiltrated by tumour.  post op radiotherapy usu indicated
86
When is radiotherapy indicated?
 Most sarcomas are radiosensitive to varying degrees.  Ewing sarcoma → very radiosensitive  Liposarcoma → relatively radiosensitive  Post op radiotherapy seems to ↓ risk of local recurrence  Esp. indicated in → high grade lesions, incomplete excisions, > 5cm lesions, deep sarcomas of head and neck region.
87
What are desmoid tumours?
 Tumour of musculoaponeurotic system (mesothelium)  Myofibroblast is main cell  Commonest in rectus sheath in post partum women  Although histologically benign, can be locally invasive and also cause morbidity due to pressure effect  So manage like sarcoma
88
What treatment is there for common peroneal nerve palsy?
Shah Tib post via interosseus membrane - inc adhesions Tib post routed medially to tib ant or peroneus - foot dorsiflexion or eversion 90% get active function range 6-85 degrees 90% functional gait
89
What does Complex Decongestive Therapy (= Decongestive Lymphatic Therapy) consist of?
1. Manual lymphatic drainage 2. Multilayer lymphoedema bandaging 3. Remedial exercises (active muscles in limb to improve drainage) 4. Skin care Intensive phase - daily for up to 6wks Maintenance phase, 6mthly reviews
90
What evidence is there for liposuction in lymph oedema treatment?
In a case series, 35 patients underwent liposuction combined with controlled compression therapy (CCT) and 14 underwent CCT alone. CCT involves wearing a custom-made sleeve-and-glove garment taken in gradually and replaced with new custom-made garments, usually at 3, 6 and 12 months after the operation. Compared with baseline, mean reductions in oedema volume at 12 months were 103% and 50%, respectively, for the two groups (p < 0.0001). All pts had reductions in self-rated pain, swelling and fatigue, and increases in mobility and activities of daily living at 12-month follow-up (p < 0.01 for all outcomes). In the 14 patients treated with CCT alone, only swelling of the arm improved significantly (p < 0.04). A non-randomised study using matched-pairs analysis (n = 16 in each group) reported that liposuction with CCT was significantly more effective in reducing oedema volume than CCT alone (p < 0.0001). In the above study and in a further case series of 28 patients, mean pre treatment oedema volumes of 1745 ml and 1845 ml were reduced to 30 ml and –122 ml (that is, the removed oedema volume exceeded the baseline volume), respectively, at 12-month follow-up. Adverse events include haemorrhage, skin necrosis, infection, bruising, pain, scarring and neurovascular injury
91
What physiologic surgery is available? What is the evidence to support it?
Physiologic procedures attempt to improve lymphatic drainage. - buried dermal flaps - omental transposition - enteromesenteric bridging - lymphangioplasty - microvascular lympholymphatic anastomosis None of these techniques has clearly documented favorable long-term results. Venous-lymphatic anastomosis - performed in patients with severe lymphedema and a functioning venous system - literature suggest this is effective only in secondary lymphedema
92
What is compartment syndrome?
It is a limb-threatening and potentially life-threatening condition when perfusion pressure falls below tissue pressure / compartment pressure, which will lead to tissue necrosis, renal failure and death if untreated. Local blood flow = (Pa - Pv) / resistance Reduced Pa - high elevation, premorbid limb ischaemia Increased Pv - limb dependency, high interstitial pressure Tissue perfusion = cap perfusion pressure - interstitial perfusion pressure CPP = 25mmHg IPP = 4mmHg (if it rises above 30mmHg, capillaries will collapse) Anaerobic metabolism, lactic acid accumulation, Na pump fails, further increase in oedema and compression Reperfusion generates free radicals and causes further injury
93
What is the aetiology of compartment syndrome?
- crush - prolonged extrinsic compression (lying in 1 posn, POP, antishock trousers) - burns - fractures - vascular injury: extravasation, bleeding from fractures, reperfusion - swelling of soft tissue (electrical injury, myositis, nephrotic syndrome, excessive exercise)
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What investigations may be indicated?
``` Diagnosis of clinical suspicion Compartment pressures Doppler / arteriography / MRI (usu chronic cases) Serum potassium, CK, clotting profile Urine myoglobin ```
95
What is the management of compartment syndrome?
Release extrinsic compression emergent fasciotomy, splint in position of function, elevation anticipate myoglobinuria - fluid resus, mannitol, dialysis Wound closure / SSG (shoelace, vessel loop techniques, Sure-Closure device, VAC assisted dermal recruitment, suture tension adjustment reel STAR) HBO
96
How do you perform fasciotomies of - foot - thigh - upper arm - forearm - hands
Foot - 2 dorsal incisions in 2nd and 4th interMT spaces (interossei, central lateral and medial comp) Thigh - medial and lateral incisions (medial and ant/post compartments) Upper arm - medial and lateral incisions (medial and post compartments) - avoid ulnar and radial nerves Forearm Dorsal - epicondyle to middle MC Volar - CTR, curve ulnarly (avoid exposing FCR) then radially at elbow (avoid ulnar nerve) Hands Dorsal - 2nd and 4th interMC spaces (AdP and interossei) Volar - thenar, hypothenar eminences, CT
97
What are the recipient vessels for free tissue transfer?
Posterior tibial artery - end to side - Godina muscle splitting approach: pt in lateral decubitus position, op leg down, split through 2 heads of gastroc and soleus, outside zone of injury, may simultaneously harvest vein (SSV) and nerve (sural) grafts Geniculate vessels Vein grafts: Anastomose distal LSV to superficial femoral artery (AV fistula). Divide loop and anstomose to donor vessels Flow through flaps - ALT, RFFF Cross leg free flap (anastomose to contralateral leg, inset to injured leg, allow neovascularisation and divide pedicle after 4wks, possibly longer for muscle flaps)
98
Justify why you are using a free ALT to cover this lower leg wound?
High energy injury, surrounding zone of injury makes local FC options unsuitable. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC, can be re-elevated with relative ease if required, better donor and recipient cosmesis.
98
Justify why you are using a free ALT to cover this lower leg wound?
High energy injury, surrounding zone of injury makes local FC options unsuitable. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC, can be re-elevated with relative ease if required, better donor and recipient cosmesis.
98
Justify why you are using a free ALT to cover this lower leg wound?
High energy injury, surrounding zone of injury makes local FC options unsuitable. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC, can be re-elevated with relative ease if required, better donor and recipient cosmesis.
98
Justify why you are using a free ALT to cover this lower leg wound?
High energy injury, surrounding zone of injury makes local FC options unsuitable. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC, can be re-elevated with relative ease if required, better donor and recipient cosmesis.
98
Justify why you are using a free ALT to cover this lower leg wound?
High energy injury, surrounding zone of injury makes local FC options unsuitable. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC, can be re-elevated with relative ease if required, better donor and recipient cosmesis.
98
Justify why you are using a free ALT to cover this lower leg wound?
High energy injury, surrounding zone of injury makes local FC options unsuitable. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC, can be re-elevated with relative ease if required, better donor and recipient cosmesis.
98
Justify why you are using a free ALT to cover this lower leg wound?
High energy injury, surrounding zone of injury makes local FC options unsuitable. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC, can be re-elevated with relative ease if required, better donor and recipient cosmesis.
98
Justify why you are using a free ALT to cover this lower leg wound?
High energy injury, surrounding zone of injury makes local FC options unsuitable. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC, can be re-elevated with relative ease if required, better donor and recipient cosmesis.
98
Justify why you are using a free ALT to cover this lower leg wound?
High energy injury, surrounding zone of injury makes local FC options unsuitable. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC, can be re-elevated with relative ease if required, better donor and recipient cosmesis.
108
Justify why you are using a free ALT to cover this lower leg wound?
1. High energy injury, surrounding zone of injury makes local FC options unsuitable. 2. Position of wound - distal 1/3 ALT - FC flap, no definitive literature to suggest muscle is superior over FC. 3. Can be re-elevated with relative ease if required, better donor and recipient cosmesis.