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Immunohematology > Chapt 4 Genetics > Flashcards

Chapt 4 Genetics Flashcards

1
Q

Chromosome

A

Threads of DNA found in the nucleus of a cell, Genes are found along the strands, Humans have 23 pairs of chromosomes

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2
Q

Gene

A

Units of inheritance

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3
Q

Homozygous

A

Inheritance of like genes at a chromosomal locus

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4
Q

Dosage

A

Stronger expression due to homozygous state of inheritance

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5
Q

Meiosis

A

Cell division producing gametes (egg & sperm), cells containing a haploid # of 23 chromosomes

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6
Q

Linkage

A

Genes are linked together on a chromosome

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7
Q

Dominant trait

A

A gene product that is expressed to the exclusion of the expression of its allele, these traits are expressed in both homozygous & heterozygous states

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8
Q

Co-Dominant Traits

A

Equal expression of 2 different inherited alleles, most blood group genes produce co-dominant traits

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9
Q

Alleles

A

Alternate forms of a gene that may be present at a single chromosome locus

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10
Q

Phenotype

A

Observable expression of inherited traits

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11
Q

Sex chromosomes

A

X/Y chromosomes that determine sex, Males=XY, Females=XX

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12
Q

Locus

A

Site of a gene on a chromosome

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13
Q

Heterozygous

A

Inheritance of 2 different alleles at a given locus

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14
Q

Crossing over

A

Exchange of genetic material during meiosis between paired chromosomes, resulting in a recombination of genetic information on these chromosomes

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15
Q

Mitosis

A

Cell division that results in diploid # (23 pairs) of chromosomes, all cells except sex cells (egg & sperm) undergo mitosis

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16
Q

Amorphic gene

A

Describes a gene that does not produce a serologically detectable product; a silent allele

17
Q

Recessive gene

A

Trait that is expressed only if the gene is inherited in double dose (homozygous)

18
Q

Traits

A

Inherited characteristic that is an expression of the actions of a gene

19
Q

Genotype

A

Actual genes inherited; often can be determined only with family studies

Immunohematology (8 decks)

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