Chapt 11 Other Blood Group Systems

Question 1

Donath-Landsteiner test

Answer 1

test designed to identify the biphasic antibody in paroxysmal cold hemoglobinuria, the sample is kept warm after collection, cooled, & then returned to 37 degrees C, hemolysis in the test but not in the control is considered a positive test

Question 2

high-incidence antigens antigen

Answer 2

antigen occurring in a large percentage of the population

Question 3

high titer, low avidity antibody

Answer 3

an antibody that is present to a high dilution, but the strength of reaction is not higher at lower dilutions than at higher dilutions, for example, an antibody that shows agglutination with RBCs at a dilution of 1:512, but the reaction strength of all tubes is only 1+

Question 4

low-incidence antigen

Answer 4

an antigen that occurs in a low number of people in a population, usually less than 10%

Question 5

sialoglycoprotein

Answer 5

combination of sialic acid glycoprotein (which is, itself, a combination of sugar & protein)

Question 6

silent allele

Answer 6

an allele that does not produce a detectable product