chap 14 Flashcards
involves alteration of supposed action of antimicrobial against the target pathogens
antibiotics resistance
involves disturbance in organisms physiology
biologic mediated resistance
due to changes in PH of environment, oxygen level or cation concentration of the antibiotics
environmental mediated resistance
observed when various bacterial strains create different susceptibility patterns
clinical mediated resistance
form of resistance that develop as result of normal physiologic and biochemical make up of bacteria
intrinsic resistance
passed vertically in new cell
intrinsic resistance
caused by changes in genetic structure of the microorganism
acquired resistance
other name of b (beta) lactamase
penicillinase or cephalosporinase
most clinically important b lactmase
class a and c
class a and d
serine peptidase
class b
metalloenzyme
class c
cephalosporinase
class d beta lactamse is commonly identified as
OXA
mosy commonly isolated b lactamase in gram negative bacteria
TEM-1
most common of chromosomal b lactamse found in a species
SHV - 1