Ch.4 - Histology Flashcards
What are the four primary tissue types
Epithelial tissues
connective tissue’s
muscle tissues
nervous tissues
Histology
Study of normal structures of tissues
epithelial tissues
Tightly packed sheets of cells with no visible ECM; cover and line all body surfaces and cavities; specialized form glands that manufacture secretion such a sweat saliva or chemical messengers called hormones
Connective tissue’s
Connect all other tissues and body to one another; ECM is a prominent feature for most connective tissue types with cells scattered throughout; bind, support, protect, and allow for transportation of substances
Muscle tissues
Capable of generating forced by contracting; little ECM between cells
Nervous tissue’s
Consisting of cells capable of generating, sending, receiving messages, and sells the support this activity all within a unique ECM
Extracellular matrix
Composed of substances in a liquid, Joe, or solid that around cells of a tissue
What are the two main components of the extracellular matrix
Ground substance and protein fibers
What are the functions of the ECM (extracellular matrix)
Provides tissue with strength to resist tensile (stretching) and compressive forces,
direct sales to their proper positions within a tissue and hold cells in place,
regulates development, mitotic activity, and survival of cells anything if you
Ground substance
Makes up most of ECM and consist of extracellular fluid; components include water nutrients ions and three families of micro molecules
what are the three families of macromolecules found in ground substance
Glycosaminoglycan’s,
proteoglycans,
cell adhesion molecules
Proteoglycans
Bound to a protein core helps make ECM firm or more solid and resistant to compression by “aggregation”
Cell adhesion molecules
Made up of different types of glycoproteins
adheres surroundings; holds everything in place within the ECM,
maintains normal tissue agriculture
Protein fibers
Embedded within ground substance; long molecules composed of multiple fibrous subunits with a rope like structure; enormous tensile strength
What are the three protein fibers found within the ECM
Collagen fibers, elastic fibers, reticular fibers
Collagen fibers
Make up 20–25% of all proteins in the body; composed of multiple repeating subunits that form a white fibrous proteins; resistant to tension (pulling a stretching forces) and pressure
Elastic fibers
Composed of protein elastin surrounded by glycoproteins; extensibility allows fiber to stretch up to 1 1/2 times resting length without breaking; once stretched, fibers return to resting length
Reticular fibers
Thin, short collagen fibers; form a meshwork of scaffold the support cells and ground substance of many tissues; form a weblike structure in organs like the spleen that help trap foreign cells
What are some diseases of collagen and elastic fibers (two)
Ehlers- Danlos syndrome,
Marfan syndrome
Ehlers Danlos syndrome
Abnormal collagen fibers; re-current joint dislocation, hyperextensibility of skin, fragility of blood vessels, easy bruising, plus various effects and intestines, heart, and lungs
Marfan syndrome
Abnormal elastic fibers; tall stature with long limbs and fingers; multiple skeletal abnormalities, recurrent joint dislocations, heart valve and lens (eye) abnormalities and dilation of aorta; aortic dissection(rupture) is most lethal complication
Cell junctions
Ways that cells bind to one another
What are the three major types of cell junctions
Tight junctions,
desmosomes,
gap junctions
Tight junctions
Hold cells closely together such that the space between is impermeable to movement of macromolecules
Where might tight junctions be found
Between cells and blood vessels; to prevent blood from exiting vessels
Desmosomes
Composed of linking integral proteins; allow for materials and extracellular fluid to pass through space between cells
Where might desmosomes be found
In tissues subjected to a great deal of mechanical stress such as epithelia of skin
Gap junctions
Small pores formed by protein channels between adjacent cells that allow small substances to flow freely between each cell cytoplasm
Where are my gap junctions be found
Between cells that communicate with electrical signals such as cardiac muscle cells
What are the functions of epithelial tissues (five)
Protection, immune defenses, secretion, transport into other tissues, sensation
What does ground substance Generally look like
Clear or has a slight tinge of color generally look like wavy or straight lines
What kind of junctions does epithelial tissues consist of
Tight junctions and desmosomes
What issues are avascular
Epithelial tissues
Define avascular
Lack blood vessels and must obtain oxygen and nutrients by the fusion from deeper tissues
Are the two components of a basement membrane
Basal lamina, reticular lamina
Basal limina
ECM synthesized by epithelial cells consist of collagen fibers and ground substance
Reticular lamina
Synthesized by underlying connective tissue; consists of reticular fibers and ground substance
Together what does basal and reticular Lamina do?
Together these two layers “Glue “epithelial tissue to underlying connective tissue ; anchor underlying blood vessels in place; provide a barrier between epithelia an underlying tissues
Epithelial tissue is classified based on two criteria’s by the number of cell layers and shape of the cells in those layers known as
Simple epithelia and stratified epithelium
Simple epithelium
Consist of a single cell layer
Stratified epithelia
Consist of more than one cell layer
What are the three epithelial tissue shapes
Squamous cells – flattened
cuboidal cells – short
columnar cells – tall and elongated
What are the four types of simple epithelia
Simple squamous epithelium,
simple cuboidal epithelium,
simple columnar epithelium,
pseudostratified columnar epithelium
Simple squamous epithelium
Very thin single layer of cells; adapter for rapid diffusion of a substance is like oxygen carbon ,dioxide fluids, and ions
Where can simple squamous epithelium be found
In the air sacs of lungs, specific segments of the kidney tubules, and lining blood vessels
Simple cuboidal epithelium
Single layer of cube shaped cells with large central nucleus did enough for rapid substance to fusion,
Where can simple cuboidal epithelium be found
Segments of renal tubule’s, respiratory passages, ducts of many glands, and thyroid gland
Simple columnar epithelium
Single layer of rectangular shaped cells with nuclei located in basil portion of cell, often as Microvilli or cilia
Where might simple columnar epithelium be found
Small intestines,
Uterine tubes and segments of the respiratory tract
Pseudostratified columnar epithelium
Appears to be layered because nuclei are formed at various heights but only one cell layer thick with basil plasma membrane’s family in contact with basement membrane