ch4 Flashcards
Charactersitics of epithelial tissue
cellularity (composed of all cells with little extracellular matrix)
polarity (apical surface and basal surface, lateral surface w intercellular junctions.)
attachment to basement membrane (in the basal surface the epithelial layer is bound to basement membrane)
avascularity (lack of tissues and blood vessels)
innervation (detect changes in enviro)
high regen capacity (apical surface damaged more frequently, so they replace themselves quick through mitotic divison of deep epithelial cells(stem cells) near basement membran)
how do epithelial cells obtain nutrients
from apical surface or diffusion on basal surface from connective tissue
what can be on the apical surface
cilia or microvilli
what is attached to the basal surface
epithelium in basal surface attached to a basement membrane which is part of both the epithelium and connective tissue underneath
functions of epithelial tissue
physical protection
selective permability
secretion
sensation
what do epithelial tissues protect against
dehydration, abrasion, and phyisical chemical or biological destruction
what are exocrine glands
epithelial cells specialized to produce secretions. can either be scattered or clumped to form a gland
neuroepithelium
a specialized epithelium hat some organs contain that house specific cells that a responsble for senses like taste, smell, vision, hearing, and equilibrium
why dont epithelial cells contain blood vessels?
to prevent bleeding bc this cell is frequently injured, and bc its protective function would be compromised
3 layers of basemement membrane and what do they contain
lamina lucida, lamina densa( both of these have protein and collagen) and reticular lamina (has protein and carbs)
functions of the basement membrane
1 physical support for epithelium
2 anchors epithelium to connective tissue
3 barrier to reg movement of large molecules btwn epi and underlying tissue
intercellular junctions
speciliazed connections in plasma membranes of the lateral surfaces of eipthelial cells that bind them together
types of intercellular junctions
tight, adhering, desmosomes, and gap junctions
tight junctions
encircle cells near their surface and completely attach each cell to its neighbor. very tightly sealed, forcing all materials to move through the cells instead of between them. allows them to control anything that enters the body
adhering junctions
located deep to tight junctions. microfillaments extend from cytoplasm into plasma membrane that completely circles the cell. they have a bit more space between them allowing things that have already passed through the tight junctions on the surface to pass between the cells instead of thru on their way to the basement membrane.
desmosome
like a button between epithelial cells. each cell contributes half of the complete desmosome. they dont cover the whole cel and only attach to neighboring cells at potential stress points
gap junctions
formed across gap btwn neighboring cells. bridged by connexons. they provide passageways for small molecules into neighboring cells, allowing for ions, glucose, and amino acids to pas thru. also in muscle tissue to help with contractions.
what intercellular junction provides resistance to mechanical stress at a single point
desmosomes
hemidesmosomes
some basal cels have half demisomes that anchor them to the basement membrane
simple epithelium and wher eis it found
one cell layer so all cells touch basement membrane. found where stress is minimal and diffusion/filtration/absorption/secretion is the main function (air sace, intestines, blood vessels)
stratified epithelium and whre is it found
2 or more layers of epithelial cells. only deep cells touch basement. multiple layesr make it strong so it is found in areas subjected to more stress (skin, esophagus, vagina) cells in basal layer continually regen as the apical cells are lost from damage
pseudostratified epithelium
appears layered bc nucleui are at dif levels but all of the cells are actually attached to basement membrane. some cells dont reach apical surface. (nasal cavity, respiratory passageways)
squamous cells
flat, wide, irregular shaped. nucleus looks like flat disc, cells look like irregular floor tiles.
cuboidal cell shape
as tall as they are wide, not perfect cubes bc rounded edges. nucleus spherical and in center of cell.
columnar shaped cells
slender, tall. look like hexagonal columns. nucleus oval and sits lenthwise in basal region.
transitional shaped cells
can change shape depending on how stretched epithelium becomes. (bladder, etc) polyhedral when cell is relaxed, looks squamous when stretched.
types of simple epithelium
simple squamous, simple cuboidal, simple columnar, pseudostratified columnar
types of stratified epithelium
transitional, stratified columnar, stratified cuboidal, stratified squamous(keratinized and nonkeratinized)
simple squamous epithelium
STRUCTURE:single layer of thin flat cells like floor tiles, nucleus bulges at center of each cell
FUNCTION: rapid diffusion and filtration, some secretion in serous membranes
LOCATION: amnion, inner later of membran around embry, air sacs, lining of heart, blood vessels, serous membrans of body cavities
simple cuboidal epithelium
STRUCTURE:single layer tall and wide ells, spherical, central nucleus
FUNCTION:absorption and secretion
LOCATION:kidney tubules, thyroud follicles, ducst and secretory regions of most glands, surface of ovaries,
NONCILIATED SIMPLE COLUMNAR EPITHELIUM
STRUCTURE:single layer of tall narow cells, oval nuc lengthwise at basal, apical reg has macrovili, can contain goblet cells
FUNCTION:absorbtion and secretion, secretion of mucin
LOCATION:lining of digestive tract, lining of stomach does not contain goblet cells
ciliated simple columnar epithelium
STRUCTURE: same as nonciliated but without microvilli.
FUNCTION: secretion of mucin and movement along apical surface with the cilia. oocyte movement thru uterine tube.
LOCATION: lining of uterine tubes and larger bronchioles of resp tract
pseudostratified columnar epithelium
STRUCTURE:single layer. varying heights that look multilayered. all cells connect basement membrane but not all to apical. ciliated form has goblet cells and cilia, nonciliated form does not.
FUNCTION: protection, ciliated forms secrete mucin and movement
LOCATION: ciliated lines resp tract like nasal, pharynx, larynx, trachea, bronchi. nonciliated isRARE, lines epididymus and male urethra.
endothelium
simple squamous epithelium that lines lumen of blood, lymphatic vessels, and heart
mesothelium
simple squamous epithelium of the serous membrane that lines internal walls of pericardial, pleural, and peritoneal cavities as well as external surfaces of organs withtin those cavities
brush border
what microvili appear as when viewd with light microscopy. lookslike a fuzzy structure
mucin
a glycoprotein secreted by mucin that when hydrated forms mucus.
keratinized vs nonkeratinized stratified squamous epithelium
STRUCTURE:multiple layers of cells, basal cells cuboidal/polyhedral, apical cells squamous.
keratinized-more superficials cells dead and filled with keratin
nonkeratinized-superficial cells are alive and kept moist
FUNCTION:protection of underlying tissue
LOCATION:
keratinized- epidermis of skin
nonkeratinized-lining of vagina, oral cavity, pharynx, espohagus, and anus
stratified cuboidal epithelium
STRUCTURE:2+ layers, cells are apical surface cuboidal
FUNCTION: protection and secretion
LOCATION: large ducts in exocrine glands and some parts of male urethra
stratified columnar epithelium
STRUCTURE: 2+ layers of cells, cells at apical surface columnar
FUNCTION: protection and secretion
LOCATION: rare, found in regions of male urethra and large ducts of exocrine glands
transitional epithelium
STRUCTURE: appearance varies depending on whether stretched or relzxed. some cels may be binucleated
FUNCTION: distension and relaxtation to accomodate urin volume changes
LOCATION: lining of bladder, ureters, and urethra
glands
individual or multicellular, composed of mostly epithelial tissue. secrete substances for use in body or for elimination from body (mucin, electolytes, hormones, enzyms, waste)
endocrine glands
lack ducts and secrete direct to blood and intersitital fluid. secrete hormones that are chem messenges to influence activites in other parts of bvody
exocrine glands
maintain contact with epithelial surface through a duct. secretes onto skin or epithelial surfaces lining passageways
(Sweat, milk, enzymes)
connective tissue
most diverse and widely used version of tissue. supports, protects, and binds organs. glue that holds body structure together
what do all connective tissues share
cells, protein fibers, and ground substance
how are connective tissue cells and epithelial cells different
connective tissue cells are scattered, whereas some epi cells are clumped together
three types of protein fibers and what they signify ab the funciton of connective tissues
collagen fibers (strong and strech resistant)
elastic fibers (flexible and reslient)
reticular fibers (for interwoven framework)
ground substance, what is it and what types are there
nonlibving material produced by connective tissue cells. made of protein and carb molecules and some water.
can be viscous (blood), semisolid (cartilage), or solid (bone).
extracellular matrix
formed by ground substance and protein fibers. most connective tissue is composed majority of this with smaller amount of cells.
functions of connective tissue
phys protection, support and structural framework, binding of structure, storage, transport, immune protection
how does connective tissue provide physical protection
bones protect organs