Ch.3, Causal Factors/Viewpoints Flashcards
Variable risk factor vs fixed marker
If predictor X can be changed = variable risk factor for outcome Y, if not, and it can only be that one thing, then it is a fixed marker of outcome Y
If changing X does NOT lead to a change in Y, X is a variable marker
If changing X DOES change Y, X can be a causal risk factor
Risk factor
if X is proven to occur before Y, we can infer that X is a RISK FACTOR for Y (abuse for depression)
Etiology vs Nessecary cause vs Sufficient Cause
causal pattern of abnormal behavior
Nessecary Cause: X is a charachteristic that MUST exist for the disorder: like a genetic disorder
MOST DISORDERS DO NOT HAVE NEAT NESSECARY CAUSES ITS MORE MESSY THAN THAT
Sufficient Cause: a condition that GURANTEES the occurence of a disorder; like hopelessness with depression, a sufficient cause may not be a nessecary cause so it doesn’t have to exist, but if it does = the disorder
Contributory causes
considered most in psychology
increases the probability of a disorder developing but is neither necessary nor sufficient for the disorder to occur
Distal risk factors vs proximal risk factors vs reinforcing contributory cause
distyal: causal factors that occur early in life and do not show their effects for many years
proximal: factors that operate shortly before the occurence of a disorder
REINFORCING CONTRIBUTORY CAUSE: condition that tends to maintain maladaptive behavior already occuring (like isolating from friends and family that lead to greater sense of rejection)
Bidirectionality in abnormal behavior
the effects of feedback and the existence of mutual/two way influences/ interacting causes
Diathesis stress models
describe disorders in terms of when someone has a preexisting vulnerability for that disorder and then experiences a major stressor
Additive model vs Interactive Model
diathesis (vulnerability) and stress add up over time
Person with low diathesis could still develop disorder when under high stress
Person with high diathesis could develop disorder when under low stress
INTERACTIVE MODEL: some amount of diathesis must be present before stress will have any effect
Protective factors and “steeling/inoculation” effect
protective: decrease the likelihod of negative outcomes among those at risk; ACTIVELY buffers against the likelihood of negative outcome (not just the absence of a risk factor)
when a person scuessfully deals with a stressful experience and experiences a positive outcome = steeling/inoculation effect = MORE LIKELY TO ONLY WORK WITH MODERATE STRESSORS, not mild or extreme
Resilience/ Multicausal development models
may be produced by protective factors= ability to adapt successfully to difficult circumstances
children who show resilience in one domain may not in another: not nessecarily holistic, and the person may even report high levels of emotional distress while being resilient
Multicausal: in the course of development child may acquire a variety of cumulative risk factors interacting to determine their risk for psychopathology
Developmental psychopathology
which concentrates on determining what is abnormal at any point in development by comparing and contrasting it with the normal and expected changes that occur in the course of development
Biological perspective of psychopathology; genotype/phenotype
first recognized with the gross destruction of brain tissue
genetic vulnerabilities: genetic predisposition to it; carriers of info we inherit from parents
brain dysfunction and neural plasticity
neurotransmitter/hormonmal imbalances
temperment
genotype, genetic makeup, phenotype, observed characteristics phenotype
Chromosomes; Polymorphisms
23 pairs, chain-like structures within a cell nucleus that contain the genes.
Last pair is sex chromosomes,XX female XY male
Polymorphisms: most mental disorders are influenced by naturally occuring variations of genes
Polygenic: disorders are influenced by multiple genes or multiple polymorphisms
ALL ONLY IMPACT BEHAVIOR INDIRECTLY
Genotype/environment interactions
genetic factors are not necessary and sufficient to cause mental disorders but instead can contribute to a vulnerability or diathesis to develop psychopathology that only happens if there is a significant stressor in the person’s life (as in the diathesis–stress models described earlier)
Types of genotype/environment interactions: pasive, evocative, active
passive: what is inherited passively; what parents do like a good home environment
evocative: child evokes reaction from environment= happy children evoke more positive responses from environment
Active effect: child seeks out or builds environment particular to their genotype, “niche building” like following their musical or social ability
Behavior genetics: family/pedigree method, twin method, adoption method
field that focuses on the heritability of mental disorders
family/pedigree method: requires that an investigator observe samples of relatives of each proband or index case (the subject, or carrier, of the trait or disorder in question) to see whether the incidence increases in proportion to the degree of hereditary relationship. the incidence of the disorder in a normal population is compared (as a control) with its incidence among the relatives of the index cases. PROBLEM: people who are closely related tend to share more similar environments, can’t tell which one it is
twin method: no disorder for which the concordance rate is 100%,
adoption method: first way one variation on this method, the biological parents of individuals who have a given disorder (and who were adopted away shortly after birth) are compared with the biological parents of individuals without the disorder (who also were adopted away shortly after birth) to determine their rates of disorder. If there is a genetic influence, one expects to find higher rates of the disorder in the biological relatives of those with the disorder than in those without the disorder; In another variation, researchers compare the rates of disorder in the adopted-away offspring of biological parents who have a disorder with those seen in the adopted-away offspring of normal biological parents.
Concordance rate; monozygotic vs dizygotic concordance rates
the percentage of twins sharing the disorder or trait
mono= much higher ; identical
di= much lower, two diff eggs
shared vs nonshared environmental influences
shared: would make children ina family more similar
nonshared: make them more different such as difference in parent treatment
Linkage analysis vs association studies
studies of mental disorders that capitalize on several currently known locations on chromosomes of genes for other inherited physical characteristics or biological processes
like conducting a family study large scale on schizophrenia, but also keep track of something like eye color
ASSOCIATION STUDIES: start with two large groups of people, one group with and one group without a disorder, researchers then compare frequencies in these two groups of certain genetic markers
Prenatal experiences vs postnatal experiences
environment enriched prenatakl rats= offspring with more neural plasticity
Postnatal: enriched environments=rats have more rich synapses and p[hysical excersie associated with neurogenesis
Developmental systems approach
acknowledges that genetics influence neural activity, which in turn influences behavior and then environment but everything is bidirectional
Synapse, neurotransmitter, types NT imbalances
synapse: gapo betwen presynpatic and postsynpatic
NTS: chemical substance released into synapse by presynpatic
NT imbalances: excessive productiona dn release into synapses, NTs become deactivated too quickly in the synapse, receptors may be insensitive or too sensitive
Monamine oxidase
gets rid of extra neurotransmitter
Chemical circuits
neurons that are sensitive to particular NT cluster together
5 NTs most closely related to psychopathology
Norepinephrine= fight/fliught, attention, basic mtovies
dopamine= cognitive processing, reward
serotonin=behavior moods, anxiety, depression, suicide
glutamate=excitatory, schizoprhenia
GABA (gamma aminobutyric acid) = reduce anxiety, inhibitory
norepinephrine, dopamine, serotonin = monamies (Each is synthesized from single amino acid)
Agonists vs antagonists
agonists: medications that facilitate the effects of a NT on the postsynpatic neuron
Antagonists: OPPOSE or inhi9bit the effects of a NT on a postsynaptic neuron
Hormones, pituitary gland, neuroendocrine system
hromones: chemical messengers secreted by endocrine glands
neuroendocrine system: CNS is linked to the endocrine system by the effects of the hypothalamus on pituiatry
Pituitary: master gland
Hypothalamus controls pituitary
Hypothalamic-pituitary-adrenal HPA axis activation/ negative feedback loop
- Messages in the form of corticotropin-releasing hormone (CRH) travel from the hypothalamus to the pituitary.
- In response to CRH, the pituitary releases adrenocorticotropic hormone (ACTH), which stimulates the cortical part of the adrenal gland (located on top of the kidney) to produce epinephrine (adrenaline) and the stress hormone cortisol, which are released into the general circulation. Cortisol mobilizes the body to deal with stress.
=Cortisol in turn provides negative feedback to the hypothalamus and pituitary to decrease their release of CRH and ACTH, which in turn reduces the release of adrenaline and cortisol. This negative feedback system operates much as a thermostat does to regulate temperature.
Gondal glands
produce sex hormones
Temperment
refers to a child’s reactivity and characteristic ways of self-regulation, which is believed to be biologically programmed; basis for personality development
5 dimensions of tempermnent, related to three dimensions of adult personality
: fearfulness, irritability/frustration, positive affect, activity level, and attention persistence/effortful control
RELATE TO (in order)
1) neuroticism or negative emotionality, (2) extraversion or positive emotionality, and (3) constraint (conscientiousness and agreeableness
High levels of positive affect and activity
= more likely to show high levels of mastery motivation, whereas children with high levels of fear and sadness are less likely to show mastery motivation
Behavioral inhibited vs uninhibited
inhibited: child who is hypervigilant in new settings
uninhibited” shows little fear, difficulty learning moral standards, etc