Ch3 BB AALA

Question 1

1. An ideal inhalant anesthetic has what characteristics?

Answer 1

Stable molecular structure
High potency
Low solubility in blood

Question 2

2. Some other characteristics of an ideal inhalant anesthetic?

Answer 2

Cardiovascular and respiratory systems unaffected
CNS effects reversible and nonstimulatory
Compatible with other drugs

Question 3

3. An important advantage of inhalant anesthetics for research is that the _____________ can be measured on a ___________ basis, which ensures that all animals are at a similar _________ ___________.

Answer 3

3. concentrations, continuous, anesthetic depth

Question 4

4. Vapor pressure is a measure of:

Answer 4

Volatility of the drug

Question 5

5. Vapor pressure is defined as the:

Answer 5

Maximum pressure that can be produced by the anesthetic at a given temperature and pressure.

Question 6

6. Precision vaporizers are designed to mix the correct _______ of _______ gas and anesthetic vapor to produce

Answer 6

volume, dilution, concentration

Question 7

7. True or False: Since halothane and isoflurane have nearly similar boiling points and vapor pressures, they can be used in identically manufactured vaporizors.

Answer 7

True

Question 8

8. MAC stands for:

Answer 8

minimum alveolar concentration

Question 9

9. The definition of MAC is:

Answer 9

MAC is the concentration at 1 atm that produces immobility in 50% of animals exposed to noxious stimuli.

Question 10

10. True or False: The use of alveolar anesthetic concentration as a measurement of the animal’s anesthetic level is based on the assumption that gases within the alveoli are in equilibrium with the blood exiting the lung.

Answer 10

True

Question 11

11. Which of the following factors have been found to affect MAC:

Answer 11

circadian rhythms
animal’s body temperature
age of the animal
other drugs

Question 12

12. At room temperature which inhalant anesthetic is present as both a liquid and a gas?

Answer 12

nitrous oxide

Question 13

13. At room temperature all of the currently used inhalant anesthetics are liquids with the exception of __________ .

Answer 13

nitrous oxide

Question 14

14. True or False: The blood/gas coefficient is an indication of the speed of onset.

Answer 14

True

Question 15

15. True or False: All other factors being equal, the greater the solubility of the anesthetic gas in blood the longer the equilibration time.

Answer 15

True

Question 16

16. The principal advantage of N2O is that it has ______ cardiovascular and respiratory ______ effects.

Answer 16

The principal advantage of N2O is that it has minimal cardiovascular and respiratory depressive effects.

Question 17

17. True or False: Halothane causes respiratory depression which is dose dependent.

Answer 17

True

Question 18

18. When using isoflurane, increases in cerebral blood flow can be prevented if ______ is instituted prior to the administration of isoflurane (Boarini, 1984).

Answer 18

hyperventilation

Question 19

19. True or False: Isoflurane is a ventilatory stimulant.

Answer 19

19. False: Isoflurane is a ventilatory depressant.

Question 20

20. Name three methods used to measure measuring volatile anesthetics

Answer 20

20. infrared spectroscopy, mass spectrometry, and gas chromatography.