Ch3 BB AALA Flashcards
1
Q
- An ideal inhalant anesthetic has what characteristics?
A
Stable molecular structure
High potency
Low solubility in blood
2
Q
- Some other characteristics of an ideal inhalant anesthetic?
A
Cardiovascular and respiratory systems unaffected
CNS effects reversible and nonstimulatory
Compatible with other drugs
3
Q
- An important advantage of inhalant anesthetics for research is that the _____________ can be measured on a ___________ basis, which ensures that all animals are at a similar _________ ___________.
A
- concentrations, continuous, anesthetic depth
4
Q
- Vapor pressure is a measure of:
A
Volatility of the drug
5
Q
- Vapor pressure is defined as the:
A
Maximum pressure that can be produced by the anesthetic at a given temperature and pressure.
6
Q
- Precision vaporizers are designed to mix the correct _______ of _______ gas and anesthetic vapor to produce
A
volume, dilution, concentration
7
Q
- True or False: Since halothane and isoflurane have nearly similar boiling points and vapor pressures, they can be used in identically manufactured vaporizors.
A
True
8
Q
- MAC stands for:
A
minimum alveolar concentration
9
Q
- The definition of MAC is:
A
MAC is the concentration at 1 atm that produces immobility in 50% of animals exposed to noxious stimuli.
10
Q
- True or False: The use of alveolar anesthetic concentration as a measurement of the animal’s anesthetic level is based on the assumption that gases within the alveoli are in equilibrium with the blood exiting the lung.
A
True
11
Q
- Which of the following factors have been found to affect MAC:
A
circadian rhythms
animal’s body temperature
age of the animal
other drugs
12
Q
- At room temperature which inhalant anesthetic is present as both a liquid and a gas?
A
nitrous oxide
13
Q
- At room temperature all of the currently used inhalant anesthetics are liquids with the exception of __________ .
A
nitrous oxide
14
Q
- True or False: The blood/gas coefficient is an indication of the speed of onset.
A
True
15
Q
- True or False: All other factors being equal, the greater the solubility of the anesthetic gas in blood the longer the equilibration time.
A
True
16
Q
- The principal advantage of N2O is that it has ______ cardiovascular and respiratory ______ effects.
A
The principal advantage of N2O is that it has minimal cardiovascular and respiratory depressive effects.
17
Q
- True or False: Halothane causes respiratory depression which is dose dependent.
A
True
18
Q
- When using isoflurane, increases in cerebral blood flow can be prevented if ______ is instituted prior to the administration of isoflurane (Boarini, 1984).
A
hyperventilation
19
Q
- True or False: Isoflurane is a ventilatory stimulant.
A
- False: Isoflurane is a ventilatory depressant.
20
Q
- Name three methods used to measure measuring volatile anesthetics
A
- infrared spectroscopy, mass spectrometry, and gas chromatography.
21
Q
A
22
Q
A
