Ch20 gene expression Flashcards

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1
Q

Mutation

A

change to the base sequence of DNA

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2
Q

Base substitution

A
  1. base sequence changes
  2. triplet codes for different amino acid
  3. change in primary structure
  4. change in tertiary structure
  5. active site is changed
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3
Q

Mutagenic agents

A
  1. ultraviolet radiations
  2. ionising radiation
  3. chemicals(NO2)
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4
Q

Addition/Duplication of bases

A
  1. frame shift to the right
  2. change in base sequence
  3. triplets code for different amino acids
  4. primary structure changes
  5. tertiary structure changes
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5
Q

Deletion of bases

A
  1. frame shift to the left
  2. change in base sequence
  3. triplets code for different amino acids
  4. primary structure changes
  5. tertiary structure changes
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6
Q

Reason mutation has no affect

A
  1. degenerate code
  2. affects introns
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7
Q

Genome

A

complete set of genes in the cell of an organism

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8
Q

Proteome

A

complete set of proteins the genome codes for

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9
Q

Translocation

A
  1. group of bases separate
  2. insert into DNA of different chromosome
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10
Q

Benzopyrene

A
  1. tobacco
  2. adds group to guanine
  3. can’t bind to cytosine
    4.
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11
Q

Nitrous acid

A
  1. remove NH2 form cytosine
  2. becomes uracil
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12
Q

Sequencing prokaryotic organisms

A
  1. much easier
  2. only one circular piece of DNA not associates with histones
  3. no introns
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