Ch15 Nervous coordination Flashcards

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1
Q

Nervous system

A
  1. nerve cells pass electrical impulses
  2. secrete neurotransmitters
  3. short-lived
  4. fast
  5. localised
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2
Q

Hormonal system

A
  1. produces chemicals transported by blood plasma
  2. change in hormone concentration stimulate target cell receptors
  3. long-lasting
  4. wide-spread
  5. slower
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3
Q

Resting potential of axon

A
  1. three Na+ actively transported out of axon
  2. two K+ ions actively transported into axon
  3. by sodium potassium pump
  4. Na+ channels are closed - axon is less permeable
  5. K+ ions diffuse out of axon through open channels
  6. more negative inside axon
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4
Q

Depolarisation

A
  1. Stimulus reaches threshold value
  2. Na+ channels open
  3. Na+ diffuse into axon down electrochemical gradient
  4. membrane becomes more permeable to Na+ ions
  5. depolarisation occurs
  6. inside axon becomes more positive (+40mv)
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5
Q

Repolarisation

A
  1. Potassium channels open
  2. Potassium ions diffuse out
  3. down electrochemical gradient
  4. Sodium channels occur
  5. repolarisation occurs
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6
Q

Hyperpolarisation

A
  1. Outward movement of K+ ions
  2. Sodium channels close
  3. Axon becomes more negative than usual
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7
Q

All or nothing principle

A

Once stimulus reaches threshold value, all action potentials reach same charge

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8
Q

Different protein channels

A
  1. each protein has specific tertiary shape complementary to ions
  2. ions have different shapes and charges
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9
Q

Saltatory conduction

A
  1. Myelin sheath is electrical insulator
  2. Action potential jump from node to node (of Ranvier)
  3. increases speed of conductance
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10
Q

3 Factors affecting action potential speed

A
  1. myelin sheath
  2. diameter of axon
  3. temperature
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11
Q

Diameter of axon

A
  1. greater diameter, faster speed of conductance
  2. less ion leakage
  3. membrane potential easier to maintain
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12
Q

Temperature

A
  1. higher temperature, faster speed of conductance
  2. diffusion rate increases
  3. proteins and enzymes involved(active transport and channels) can denature
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13
Q

Refractory period

A
  1. no NA+ ions can diffuse in because channels are closed
  2. no new action potential can be produced
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14
Q

Function of refractory period

A
  1. Action potentials propagated in one direction only
  2. discrete impulses
  3. limits number of action potentials
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15
Q

Transmission across cholinergenic synapse

A
  1. depolarisation of presynaptic membrane
  2. Calcium channels open and calcium ions enter synaptic knob
  3. Synaptic vesicles fuse with presynaptic membrane
  4. neurotransmitter(acetylcholine) released - exocytosis
  5. diffuses across synaptic cleft
  6. binds to receptors on postsynaptic membrane
  7. sodium channels open, sodium ions enter
  8. postsynaptic neurone is depolarised
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16
Q

Recycling acetylcholine

A
  1. acetylcholinterase hydrolyses acetylcholine
  2. ethanoic acid and choline diffuse across synaptic cleft to presynaptic neurone
  3. Sodium channels close in postsynaptic knob- no new action potentials
  4. ATP reforms acetylcholine
17
Q

Spatial summation

A
  1. different presynaptic neurones converging on one synapse
  2. release enough neurotransmitter at same time to exceed threshold value
  3. Action potential produced
18
Q

Temporal summation

A
  1. One neurone release neurotransmitter many times over short period
  2. Neurotransmitter accumulate to exceed threshold value
  3. Action potential produced
19
Q

Mitochondria use

A
  1. Maintain active transport ions in sodium potassium pump
  2. Synthesis of neurotransmitter
  3. Movement of vesicles
  4. Synthesis of enzyme acetylcholinterase
20
Q

Unidirectionality

A
  1. Synaptic vesicles with neurotransmitter only synthesised in presynaptic neurone
  2. Neurotransmitter receptor only located at postsynaptic neurone
  3. Neurotransmitter diffused down concentration gradient
21
Q

Inhibition

A
  1. Neurotransmitter binds to receptor
  2. K+ and Cl- channels open
  3. K+ passes out and Cl- passes in
  4. Membrane potential hyperpolarised
  5. increased stimulation needed to reach threshold value
  6. more Na+ required