Ch16 Kidney Flashcards
1
Q
Osmoregulation
A
- Ultrafiltration
- Reabsorption
- Medulla Na+ gradient
- Reabsorption of water
2
Q
Ultrafiltration
A
- Hydrostatic pressure in glomerulus than bowman’s capsule
- Small molecules such as water, glucose and ions
- pass through basement membrane
- proteins are too large to go through
- podocytes in renal capsule
- glomerular filtrate produced
3
Q
Adaptations of glomerulus
A
- afferent arteriole has greater diameter of efferent arteriole
- high hydrostatic pressure
- endothelium have pores(filtrate)
- podocytes
4
Q
Reabsorption
A
- Na+ actively transported out of proximal convoluted tubule into blood capillaries
- Na+ diffuse down concentration gradient from lumen into cells lining proximal convoluted tubule
- co-transport occurs with Na+ ions through carrier proteins
- glucose, amino acids and ions
- molecules then diffuse down concentration gradient into blood capillaries
5
Q
Proximal convoluted tubule adaptations
A
- microvilli and infoldings- large SA for reabsorption
- high density mitochondria to provide ATP for active transport
6
Q
Loop of Henle
A
- Na+ ions actively transported out of ascending limb
- ascending limb impermeable to water
- lowers water potential in medulla
- water moves out descending limb via osmosis
- Na+ ions diffuse into bottom of descending limb
- water leaves collecting duct via osmosis down water potential gradient
7
Q
Distal convoluted tubule
A
- reabsorbs material from filtrate via active transport
- water diffused out via osmosis down water potential gradient
- remains transported to urine
8
Q
Longer loop of Henle
A
- more ions actively transported out of ascending limb
- concentration of ions increases down medulla- lower water potential
- more water reabsorbed by osmosis
- from collecting duct into blood
9
Q
ADH low wpt
A
- detected by osmoreceptors in hypothalamus- sends nerve impulses
- posterior pituitary gland secretes ADH
- ADH increases number of aquaporins in DCT/collecting duct- more permeable
- more water is reabsorbed into blood via osmosis down water potential gradient
- more concentrated urine produced
10
Q
ADH
A
antidiuretic hormone
binds with csm receptors
activates enzyme phosphorylase
cell vesicles move and fuse with csm
increase number aquaporins
11
Q
Role of the nephron
A
- filter the blood
- removes waste
- selectively reabsorbs useful substances