Ch16 Kidney Flashcards

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1
Q

Osmoregulation

A
  1. Ultrafiltration
  2. Reabsorption
  3. Medulla Na+ gradient
  4. Reabsorption of water
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2
Q

Ultrafiltration

A
  1. Hydrostatic pressure in glomerulus than bowman’s capsule
  2. Small molecules such as water, glucose and ions
  3. pass through basement membrane
  4. proteins are too large to go through
  5. podocytes in renal capsule
  6. glomerular filtrate produced
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3
Q

Adaptations of glomerulus

A
  1. afferent arteriole has greater diameter of efferent arteriole
  2. high hydrostatic pressure
  3. endothelium have pores(filtrate)
  4. podocytes
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4
Q

Reabsorption

A
  1. Na+ actively transported out of proximal convoluted tubule into blood capillaries
  2. Na+ diffuse down concentration gradient from lumen into cells lining proximal convoluted tubule
  3. co-transport occurs with Na+ ions through carrier proteins
  4. glucose, amino acids and ions
  5. molecules then diffuse down concentration gradient into blood capillaries
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5
Q

Proximal convoluted tubule adaptations

A
  1. microvilli and infoldings- large SA for reabsorption
  2. high density mitochondria to provide ATP for active transport
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6
Q

Loop of Henle

A
  1. Na+ ions actively transported out of ascending limb
  2. ascending limb impermeable to water
  3. lowers water potential in medulla
  4. water moves out descending limb via osmosis
  5. Na+ ions diffuse into bottom of descending limb
  6. water leaves collecting duct via osmosis down water potential gradient
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7
Q

Distal convoluted tubule

A
  1. reabsorbs material from filtrate via active transport
  2. water diffused out via osmosis down water potential gradient
  3. remains transported to urine
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8
Q

Longer loop of Henle

A
  1. more ions actively transported out of ascending limb
  2. concentration of ions increases down medulla- lower water potential
  3. more water reabsorbed by osmosis
  4. from collecting duct into blood
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9
Q

ADH low wpt

A
  1. detected by osmoreceptors in hypothalamus- sends nerve impulses
  2. posterior pituitary gland secretes ADH
  3. ADH increases number of aquaporins in DCT/collecting duct- more permeable
  4. more water is reabsorbed into blood via osmosis down water potential gradient
  5. more concentrated urine produced
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10
Q

ADH

A

antidiuretic hormone
binds with csm receptors
activates enzyme phosphorylase
cell vesicles move and fuse with csm
increase number aquaporins

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11
Q

Role of the nephron

A
  1. filter the blood
  2. removes waste
  3. selectively reabsorbs useful substances
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