Ch15 Eukaryotic &Archael Genome Rep And Expression

Question 1

ORC

Answer 1

Origin recognition complex. Platform for other proteins like helicases that participate in replication

Question 2

Replicons

Answer 2

Unit of genome that contains an origin of replication where DNA is replicated

Question 3

Pre RC

Answer 3

Complex made of ORC and mini chromosome maintenance complexes surrounds both DNA strands ( G1)

Question 4

CMG helicases

Answer 4

Fully formed helicases that move away from each other and open the dsDNA to start replication during S phase

Question 5

End replication problem

Answer 5

RNA primer on 5’end of linear chromosomes results in shortening of the daughter strand b/c no 3’OH to allow for DNA pol to start replication with

Question 6

Telomeres

Answer 6

Complexes of DNA and proteins at the end of eukaryotic chromosomes.

Question 7

Telomerase

Answer 7

An enzyme that replicates the ends of chromosomes in eukaryotes

Question 8

Pre-mRNA

Answer 8

RNA transcript produced by transcription prior to processing that adds 5’ cap, 3’ poly-A tail and removal of introns

Question 9

5’cap

Answer 9

7-methylguanosine cap

Question 10

3’ tail

Answer 10

Poly A tail

Question 11

Spliceosome

Answer 11

Ribozyme that removes introns from pre-mRNA