Ch.12 "Learning and Memory" Flashcards
Alzheimer’s Disease
A disorder characterized by progressive brain deterioration and impairment of memory and other mental abilities; the most common cause of dementia.
Anterograde Amnesia
An impairment in forming new memories.
Associative Long-Term Potentiation
Strengthening of a weak synapse when it and a strong synapse on the same postsynaptic neuron are active simultaneously.
Brain-Derived Neurotrophic Factor (BDNF)
A protein that contributes to neuron growth and survival.
Confabulation
Fabrication of stories and facts, which are then accepted by the individual, to make up for those missing from memory.
Consolidation
The process in which the brain forms a permanent representation of a memory.
Declarative Memory
The memory process that records memories of facts, people, and events that the person can verbalize, or declare.
Dementia
Substantial loss of memory and other cognitive abilities usually, but not necessarily, in the elderly.
Dendritic Spines
Outgrowths from the dendrites that partially bridge the synaptic cleft and make the synapse more sensitive.
Hebb Rule
The principle stating that if an axon of a presynaptic neuron is active while the postsynaptic neuron is firing, the synapse between them will be strengthened.
(Synapse is strengthened if axon of pre is active and post is firing)
Korsakoff Syndrome
A form of dementia in which brain deterioration is almost always caused by chronic alcoholism.
Long-Term Depression (LTD)
Weakening of a synapse when stimulation of presynaptic neurons is insufficient to activate the postsynaptic neurons.
Long-Term Potentiation (LTP)
An increase in synaptic strength that occurs when presynaptic neurons and postsynaptic neurons are active simultaneously.
Neurofibrillary Tangles
Abnormal accumulations of the protein tau that develop inside neurons and are associated with the death of brain cells in people with Alzheimer’s disease and Down syndrome.
Nondeclarative Memory
Non-statable memories that result from procedural or skills learning, emotional learning, and simple conditioning.