Ch.12-13 DNA and RNA Test Flashcards

(47 cards)

1
Q

This scientist is responsible for discovering the mature of the gene in 1928. They were trying to figure out how certain types of bacteria produce pneumonia

A

Frederick Griffith

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2
Q

How did Griffith discover transformation?

A

Injecting mice with disease-causing bacteria and observing results

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3
Q

Process in which one type of bacteria is changed permanently into another

A

Transformation

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4
Q

Who discovered that DNA was the transforming factor?

A

Oswald Avery

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5
Q
  • studied viruses
  • studied bacteriophage
  • used radioactive markers to tell which molecule entered bacteria and carried genetic info
  • concluded that genetic material of the bacteriophage was DNA not protein
A

Hershey and Chase

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6
Q

A nucleic acid made up of nucleotides joined into long strands or chains by covalent bonds

A

DNA

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7
Q

3 parts of a nucleotide

A

5-carbon sugar: deoxyribose
phosphate group
nitrogenous base (A, T, C, G)

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8
Q

4 kinds of nitrogenous bases

A

adenine (A)
thymine (T)
cytosine (C)
guanine (G)

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9
Q

sugar and phosphate make up the ____ of DNA while the bases make up the ___

A

outside

inside

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10
Q

Scientist who discovered that the percentages of adenine and thymine bases re almost equal in any sample of DNA. Same thing with guanine and cytosine

A

Chargaff

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11
Q

Scientist who used x-ray diffraction to reveal X-shaped pattern of DNA and that it has 2 stands

A

Rosalind Franklin

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12
Q

Built a model that explained the specific structure and properties of DNA. Double helix. Credited with discovering structure of DNA

A

Watson and Crick

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13
Q

“antiparallel”

A

2 strands of DNA run in opposite directions

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14
Q

What type of bonds hold nitrogenous bases together?

A

hydrogen

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15
Q

enzyme that unzips two strands of DNA

A

helicase

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16
Q

principle enzyme involved in DNA replication that joins individual nucleotides to produce new strands of DNA

A

DNA polymerase

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17
Q

tips of chromosomes that contain repeated DNA sequences

A

telomeres

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18
Q

single, circular DNA molecule in prokaryotes

A

plasmid

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19
Q

3 important differences between DNA and RNA

A
-RNA sugar-ribose
 DNA sugar-deoxyribose
-RNA single stranded
 DNA double stranded
-RNA uracil
 DNA thymine
20
Q

RNA uses the base sequence copied form DNA to..

A

direct the production of proteins

21
Q

DNA stays in the nucleus while RNA…

A

go to the protein-building sites in the cytoplasm called the ribosomes

22
Q

RNA functions

A
  • protein synthesis

- assembly of amino acids

23
Q

3 types of RNA

A
messenger RNA (mRNA)
transfer RNA (tRNA)
ribosomal RNA (rRNA)
24
Q

This type of RNA carries copies of instructions from DNA

A

messenger RNA

25
This type of RNA are subunits that make up ribosomes
ribosomal RNA
26
This type of RNA transfers each amino acid to the ribosome
transfer RNA
27
During this process segments of DNA serve as templates to produce complementary RNA molecules
transcription
28
enzyme required for transcription that only bonds to promoters
RNA polymerase
29
These are the pieces that are cut out and discarded during RNA editing
introns
30
These are the pieces that remain during RNA editing
exons
31
4 nitrogenous bases of RNA
adenine uracil guanine cytosine
32
consists of 3 consecutive bases
codon
33
"start" codon
methionine
34
The decoding of an mRNA message into a protein in known as...
translation
35
Steps of translocation
1. Ribosome attaches to an mRNA molecule in the cytoplasm | 2. tRNA is directed to bring specified amino acid into ribosome
36
DNA->RNA->Proteins
Central Dogma of Biology
37
any mistake in DNA
mutations
38
2 types of mutations
Gene and Chromosomal mutations
39
What are point mutations?
mutations that occur at a single point
40
Point mutations include...
substitutions, insertions, deletions
41
Insertions and deletions are _____ mutations because they shift the reading frame of the genetic message
frameshift
42
4 types of chromosomal mutations...
deletion, duplication, inversion, translocation
43
reverses the direction of parts of a chromosome (looks like crossing over)
inversion
44
occurs when part of one chromosome breaks off and attaches to another
translocation
45
mutation causing elements
mutagens
46
pesticides, plant alkaloids, tobacco smoke are all _____ mutagens
chemical
47
x-rays and ultraviolet light are ____ mutagens
physical