Ch.12-13 DNA and RNA Test Flashcards
This scientist is responsible for discovering the mature of the gene in 1928. They were trying to figure out how certain types of bacteria produce pneumonia
Frederick Griffith
How did Griffith discover transformation?
Injecting mice with disease-causing bacteria and observing results
Process in which one type of bacteria is changed permanently into another
Transformation
Who discovered that DNA was the transforming factor?
Oswald Avery
- studied viruses
- studied bacteriophage
- used radioactive markers to tell which molecule entered bacteria and carried genetic info
- concluded that genetic material of the bacteriophage was DNA not protein
Hershey and Chase
A nucleic acid made up of nucleotides joined into long strands or chains by covalent bonds
DNA
3 parts of a nucleotide
5-carbon sugar: deoxyribose
phosphate group
nitrogenous base (A, T, C, G)
4 kinds of nitrogenous bases
adenine (A)
thymine (T)
cytosine (C)
guanine (G)
sugar and phosphate make up the ____ of DNA while the bases make up the ___
outside
inside
Scientist who discovered that the percentages of adenine and thymine bases re almost equal in any sample of DNA. Same thing with guanine and cytosine
Chargaff
Scientist who used x-ray diffraction to reveal X-shaped pattern of DNA and that it has 2 stands
Rosalind Franklin
Built a model that explained the specific structure and properties of DNA. Double helix. Credited with discovering structure of DNA
Watson and Crick
“antiparallel”
2 strands of DNA run in opposite directions
What type of bonds hold nitrogenous bases together?
hydrogen
enzyme that unzips two strands of DNA
helicase
principle enzyme involved in DNA replication that joins individual nucleotides to produce new strands of DNA
DNA polymerase
tips of chromosomes that contain repeated DNA sequences
telomeres
single, circular DNA molecule in prokaryotes
plasmid
3 important differences between DNA and RNA
-RNA sugar-ribose DNA sugar-deoxyribose -RNA single stranded DNA double stranded -RNA uracil DNA thymine
RNA uses the base sequence copied form DNA to..
direct the production of proteins
DNA stays in the nucleus while RNA…
go to the protein-building sites in the cytoplasm called the ribosomes
RNA functions
- protein synthesis
- assembly of amino acids
3 types of RNA
messenger RNA (mRNA) transfer RNA (tRNA) ribosomal RNA (rRNA)
This type of RNA carries copies of instructions from DNA
messenger RNA
This type of RNA are subunits that make up ribosomes
ribosomal RNA
This type of RNA transfers each amino acid to the ribosome
transfer RNA
During this process segments of DNA serve as templates to produce complementary RNA molecules
transcription
enzyme required for transcription that only bonds to promoters
RNA polymerase
These are the pieces that are cut out and discarded during RNA editing
introns
These are the pieces that remain during RNA editing
exons
4 nitrogenous bases of RNA
adenine
uracil
guanine
cytosine
consists of 3 consecutive bases
codon
“start” codon
methionine
The decoding of an mRNA message into a protein in known as…
translation
Steps of translocation
- Ribosome attaches to an mRNA molecule in the cytoplasm
2. tRNA is directed to bring specified amino acid into ribosome
DNA->RNA->Proteins
Central Dogma of Biology
any mistake in DNA
mutations
2 types of mutations
Gene and Chromosomal mutations
What are point mutations?
mutations that occur at a single point
Point mutations include…
substitutions, insertions, deletions
Insertions and deletions are _____ mutations because they shift the reading frame of the genetic message
frameshift
4 types of chromosomal mutations…
deletion, duplication, inversion, translocation
reverses the direction of parts of a chromosome (looks like crossing over)
inversion
occurs when part of one chromosome breaks off and attaches to another
translocation
mutation causing elements
mutagens
pesticides, plant alkaloids, tobacco smoke are all _____ mutagens
chemical
x-rays and ultraviolet light are ____ mutagens
physical