Ch. 9: The Digestive System Flashcards
Intracellular digestion
Involves the oxidation of glucose and fatty acids to make energy
Extracellular digestion
Occurs in the lumen of the alimentary canal
Mechanical digestion
Physical breakdown of large food particles into smaller food particles
Chemical digestion
Enzymatic cleavage of chemical bonds, such as peptide bonds of proteins or the glycosidic bonds of starches
Pathway of the digestive tract
oral cavity, pharynx, esophagus, stomach, small intestine, large intestine, rectum
Accessory Organs of Digestion
Salivary glands, pancreas, liver, and gallbladder
Enteric Nervous System
Wall of the alimentary canal and controls peristalsis. Its activity is upregulated by the parasympathetic nervous sys and downregulated by the sympathetic nervous sys
Hormones which regulate feeding behavior
Including antidiuretic hormone (ADH Or vasopressin) and aldosterone, which promote thirst; glucagon and ghrelin, which promote hunger; and leptin and cholecystokinin, which promote satiety
Oral Cavity
Mastication (chewing) starts the mechanical digestion of food
Salivary amylase and lipase
In the oral cavity, start the chemical digestion of food.
Bolus
Food is formed into a bolus and swallowed
Pharynx
Connects the mouth and posterior nasal cavity to the esophagus
Esophagus
Propels food to the stomach using peristalsis.
lower esophageal (cardiac) sphincter
Food enters stomach through the lower esophageal (cardiac) sphincter
Parts of the stomach
Fundas, body, antrum, and pylorus
Structure of the stomach
Lesser and greater curvature and is thrown into folds called rugae
Mucous cells
Produce bicarbonate-rich mucus to protect the stomach
Chief cells
Secrete pepsinogen, a protease activated by the acidic environment of the stomach
Parietal cells
Secrete hydrochloric acid and intrinsic factor, which is needed for vitamin B12 absorption
G-cells
Secrete gastrin
Gastrin
A peptide hormone that increases HCl secretion and gastric motility
Chyme
After mechanical and chemical digestion of food
Pyloric sphincter
Food passes into the duodenum through this
Duodenum:
First part of the small intestine and is primarily involved in chemical digestion
Disaccharides
Brush-border enzymes that break down maltose, isomaltose, lactose, and sucrose into monosaccharides
Brush-border peptidases
Include aminopeptidase and dipeptidase
Enteropeptidase
Activates trypsinogen and procarboxypeptidase, initiating and activation cascade
Secretin
Stimulates the release of pancreatic juices into the digestive tract and slows motility
Cholecystokinin
Stimulates bile release from the gallbladder, release of pancreatic juices, and satiety
Acinar cells
In the pancreas, produce pancreatic juices that contain bicarbonate, pancreatic amylase, pancreatic peptidases (trypsinogen, chymotrypsinogen, carboxypeptidases A and B) and pancreatic lipase
Liver
Synthesizes bile, processes nutrients through glycogenesis and glycogenolysis, storage and mobilization of fats, and gluconeogenesis), produces urea, detoxifies chemicals, activates or inactivates medications, and synthesizes albumin and clotting factors.
Bile
Can be stored in the gallbladder or secreted into the duodenum directly; emulsifies fats, making them soluble and increasing their surface area. Main components of bile are bile salts, pigments (especially bilirubin from the breakdown of hemoglobin) and cholesterol.
Gallbladder
Stores and concentrates bile
Jejunum and ileum
Of the small intestine, primarily involved in absorption
Villi
The small intestine is lined w villi, which are covered with microvilli increasing the surface area available for absorption. They contain a capillary bed and lacteal
Lacteal
A vessel of the lymphatic system; fat soluble compounds, such as fats, cholesterol, and fat-soluble vitamins, enter the lacteal
Villi Capillary bed
Water soluble compounds such as monosaccharides, amino acids, water-soluble vitamins, small fatty acids, and water, enter the capillary bed
Large intestine
Absorbs water and salts, forming semisolid feces
Cecum
Outpocketing that accepts fluid from the small intestine through the ileocecal valve and is the site of attachment of the appendix
Colon
Divided into ascending, transverse, descending and sigmoid portions
Rectum
Stores feces, which are then excreted through the anus
Gut bacteria
Produce vitamin K and biotin (vitamin B7)