Ch 8 Test Materials Flashcards
Muscle Structure and Force Generation
Specialized cellular composition: Muscles are made of muscle fibers (cells) containing proteins like actin and myosin. These fibers contract, sliding past each other, generating force and movement.
Types of Muscle Tissue
Skeletal muscle: Voluntary, striated, attaches to bones, and is responsible for body movement.
Cardiac muscle: Involuntary, striated, found in the heart.
Smooth muscle: Involuntary, non-striated, found in the walls of internal organs.
Connective Tissue covering muscles
Epimysium: The outer layer of connective tissue that surrounds the entire muscle.
Connective Tissue
Connective tissue consists of cells and extracellular matrix, and it supports, binds, and insulates organs and tissues.
Actin
Actin is a thin protein filament involved in muscle contraction. It forms part of the sarcomere in muscle fibers.
Myosin
Myosin is a thick protein filament that interacts with actin to produce muscle contraction.
Striations in Skeletal Muscle
Striations are caused by the arrangement of actin and myosin filaments within the muscle fiber, creating alternating light and dark bands.
Neuromuscular Junction
The site where a motor neuron meets a muscle fiber, transmitting nerve impulses for contraction.
Motor Neurons
Nerve cells that transmit electrical impulses to muscles, causing them to contract.
Neurotransmitter Secretion
Neurotransmitters (e.g., acetylcholine) are released from synaptic vesicles in the axon terminal, crossing the synapse to bind with receptors on muscle fibers.
Muscle Fiber Contraction
A muscle contracts when the motor neuron releases acetylcholine, which triggers the muscle’s action potential and initiates the sliding filament mechanism between actin and myosin.
Cross-Bridge Linkages
The connection formed when the myosin head binds to actin, allowing for muscle contraction.
Force Generation in Muscular Contraction
The force of contraction comes from the repeated cross-bridge cycling between actin and myosin filaments.
Acetylcholine (ACh)
A neurotransmitter that stimulates muscle contraction at the neuromuscular junction.
Muscle Fiber Shortening
The interaction between actin and myosin causes the sarcomere to shorten, which in turn shortens the muscle fiber.
Acetylcholinesterase
An enzyme that breaks down acetylcholine in the synaptic cleft, ending the signal and allowing the muscle to relax.
ATP
ATP (Adenosine Triphosphate) is the energy source for muscle contraction. It provides the energy needed for the cross-bridge cycle and pumps calcium back into the sarcoplasmic reticulum.
Creatine Phosphate
A molecule that helps regenerate ATP in muscles during short bursts of intense activity.
Cellular Respiration
The process by which cells produce ATP from nutrients, typically involving glycolysis, the citric acid cycle, and oxidative phosphorylation.
Aerobic Respiration
ATP production using oxygen, typically producing more ATP than anaerobic processes.
Myoglobin
A protein that binds oxygen in muscle cells, aiding in oxygen storage and delivery during muscle activity.
Oxygen Debt
The amount of oxygen required to restore muscle cells to their pre-exercise state (replenishing oxygen stores and removing lactic acid).