Ch 8 Immunity Flashcards

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1
Q

natural immunity

A

Protection against a disease formed without medical intervention.

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2
Q

artificial immunity

A

Protection against a disease formed as a result of medical intervention. Also known as induced immunity.

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3
Q

active immunity

A

Protection against a disease created by antibodies and memory cells formed by a person’s own adaptive immune system.

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4
Q

passive immunity

A

Protection against a disease created by antibodies from an external source.

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5
Q

natural active immunity

A

Protection against a disease created by antibodies and memory cells produced by an individual’s own immune system without medical intervention. Also known as naturally acquired active immunity.

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6
Q

artificial active immunity

A

Protection against a disease created by antibodies and memory cells produced by an individual’s own immune system after medical intervention. Also known as artificially acquired active immunity.

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6
Q

natural passive immunity

A

Protection against a disease created by antibodies from an external non-medical source. Also known as naturally acquired passive immunity.

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7
Q

vaccine

A

A medical treatment typically containing antigens designed to stimulate a person’s adaptive immune system to create immunity to a pathogen without actually causing disease.

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8
Q

primary immune response

A

The reaction of the adaptive immune system to an antigen it has not previously been exposed to.

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9
Q

artificial passive immunity

A

Protection against a disease created by antibodies from an external medical source. Also known as artificially acquired passive immunity.

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9
Q

vaccination program

A

A series of vaccinations designed to create long-term immunity to a disease. Also known as a vaccination schedule.

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10
Q

secondary immune response

A

The heightened reaction of the adaptive immune system to an antigen it has previously been exposed to.

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11
Q

booster vaccine

A

A vaccination given to a person later in time after they have completed their initial vaccination program to enhance their existing immunity against a disease. Also known as a booster shot.

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12
Q

antivenom

A

A medical treatment containing antibodies specific to the toxins present in venomous bites or stings.

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13
Q

herd immunity

A

Protection against a disease conferred to non-immune individuals when a high percentage of a population is immune to the same disease. Herd immunity is often achieved through high rates of vaccination.

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14
Q

pathogen

A

An agent that causes disease.

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14
Q

non-infectious disease

A

An illness not caused by a pathogen.

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15
Q

infectious disease

A

An illness caused by a pathogen.

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15
Q

virulence

A

The potential of a pathogen or disease to cause serious illness or harm.

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16
Q

contagious disease

A

An illness caused by a pathogen that can be transmitted and spread between different people.

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17
Q

contagious

A

A property of a pathogen or disease meaning that it can be transmitted from one organism to another.

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18
Q

emerging disease

A

An infectious disease that is new to the human population, or that is rapidly increasing in incidence.

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19
Q

incidence

A

The frequency of a disease in a population.

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19
Q

re-emerging disease

A

An infectious disease that was previously under control but that is now increasing in incidence.

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20
Q

reservoir

A

A population of animals or environment in which a pathogen normally lives.

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20
Q

zoonosis

A

An infectious disease that is caused by a pathogen that has transferred from an animal to a human.

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21
Q

outbreak

A

A sudden and unexpected increase in the occurrence of a disease.

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22
Q

pandemic

A

An epidemic that has spread across multiple countries and/or continents.

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22
Q

epidemic

A

A dramatically increased occurrence of a disease in a particular community at a particular time.

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22
Q

endemic

A

When a disease occurs at a relatively constant baseline level in a population.

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23
Q

natural active immunity

A

Protection against a disease created by antibodies and memory cells produced by an individual’s own immune system without medical intervention. Also known as naturally acquired active immunity.

24
Q

pathogen

A

An agent that causes disease.

25
Q

contagious

A

A property of a pathogen or disease meaning that it can be transmitted from one organism to another.

26
Q

virulence

A

The potential of a pathogen or disease to cause serious illness or harm.

27
Q

outbreak

A

A sudden and unexpected increase in the occurrence of a disease.

28
Q

epidemic

A

A dramatically increased occurrence of a disease in a particular community at a particular time.

29
Q

pandemic

A

An epidemic that has spread across multiple countries and/or continents.

30
Q

serology

A

The study of blood serum, typically to determine the presence of antibodies and/or antigens.

31
Q

serum

A

The fluid and solute component of blood that excludes blood cells, platelets, and clotting factors.

32
Q

host

A

An organism that harbours a pathogen.

33
Q

enzyme-linked immunosorbent assay (ELISA)

A

An experimental technique used to identify a pathogen by determining the presence of antigens or antibodies in a sample.

34
Q

transmission

A

The passing of a pathogen from an infected host to another individual or group.

35
Q

droplet transmission

A

The spread of pathogens through air and contaminated surfaces via respiratory droplets.

35
Q

airborne transmission

A

The spread of pathogens through air via small particles (traditionally <5 μm).

36
Q

respiratory droplets

A

Droplets (traditionally >5 μm) produced by breathing, talking, vomiting, and coughing. They may contain saliva, mucus, and other substances from the respiratory tract, including cells/particles of pathogens.

37
Q

direct physical contact transmission

A

The spread of pathogens through contact between a host and another individual.

38
Q

vertical transmission

A

Spread of pathogens from mother-to-child during gestation, during childbirth, or post-birth due to close physical contact and breastfeeding of a newborn.

39
Q

iatrogenic

A

Describes a disease caused by medical intervention.

40
Q

fomites

A

An inanimate object that, when contaminated with a pathogen, can transmit that pathogen to a new host.

41
Q

indirect physical contact transmission

A

The spread of pathogens via contaminated objects or vectors.

42
Q

vector

A

An organism that is not affected by a disease but spreads it between hosts.

42
Q

antiseptic

A

A substance that is applied to living tissue to kill or slow the growth of microorganisms.

43
Q

faecal-oral transmission

A

The spread of pathogens via oral consumption of contaminated faeces.

44
Q

antibiotic

A

Medications used to kill bacteria or slow their growth.

45
Q

disinfectant

A

A substance that is applied to non-living materials to kill or slow the growth of microorganisms.

46
Q

antiviral

A

Medications used to treat viral infections.

47
Q

fungicide

A

Medications used to treat fungal infections.

48
Q

antimicrobial resistance

A

The ability of a microorganism to survive exposure to an antimicrobial agent.

49
Q

immunotherapy

A

Medical interventions that treat disease by modulating the immune system, typically by either amplifying or reducing an immune response.

50
Q

monoclonal antibodies (mAbs)

A

Identical laboratory-made antibodies produced by plasma cell clones.

51
Q

chimeric

A

An organism or cell containing genetic material from another organism or cell.

52
Q

cancer

A

A disease caused by the uncontrolled replication of cells with the ability to migrate to other parts of the body.

53
Q

autoimmune disease

A

A disease in which an individual’s immune system initiates an immune response against their own cells.

54
Q

B lymphocyte

A

A type of lymphocyte that plays an important role in humoral immunity and differentiates into plasma cells and B memory cells.

55
Q

myeloma cells

A

Rapidly-dividing cancerous plasma cells which are fused with extracted B cells from mice to produce hybridomas.

56
Q

hybridoma

A

The product of the fusion between a mouse’s extracted plasma cell and a myeloma cell.

57
Q

naked monoclonal antibodies

A

Monoclonal antibodies that do not have any other molecules attached to them.

58
Q

conjugated monoclonal antibodies

A

Monoclonal antibodies with other molecules (e.g. chemotherapy drugs or radioisotopes) attached to them.

59
Q

complement proteins

A

A number of different types of proteins found in the blood that opsonise, cause lysis, and attract phagocytes to invading pathogens.

60
Q

membrane attack complex (MAC)

A

A pore formed by complement proteins in the cell membrane of a pathogen, disrupting the membrane and leading to the pathogen’s destruction.

61
Q

apoptosis

A

The controlled death of cells in the body. Also known as programmed cell death.

62
Q

autoantibodies

A

Antibodies directed against an organism’s own tissues.

63
Q

autoreactive

A

A cell that recognises a self-tissue or self-antigen as non-self.

64
Q

immunosuppression

A

A reduction in the ability of the immune system to generate an immune response.

65
Q

immune deficiency

A

A state in which the immune system is no longer able to protect the body against infection or disease. Also known as immunodeficiency.