Ch. 8 Genomics And Gene Expression Flashcards
Which of the following is utilized in genomic research?
All of the above
- micro-satellite polymorphism
- restriction fragment length polymorphism
- single nucleotide polymorphism
- variable number tandem repeat
What is contig mapping?
Determination of regions that overlap from one clone to the next in a library
Assembly of these adjacent, overlapping (“contiguous”) maps allows a complete restriction map to be assembled for the entire region
Which method was used to sequence the human genome?
All of the above were used in combination to complete the project.
- cytogenetic mapping
- shotgun sequencing
- chromosome walking
- radiation hybrid mapping
Which organism has the most genes?
P. trichocarpa
What is a gene?
All of the above
- a segment of DNA that encodes a protein
- a segment of DNA that encodes non-translated RNA
- sequences of DNA that are not transcribed
- a segment of DNA that is transcribed
Which of the following is considered a field of study related to bioinformatics?
All of the above.
- proteomics
- computational biology
- genomics
- cheminformatics
How is data mining useful to biotechnology research?
Data mining allows researchers to use computers to study, sort, and compile the vast amounts of raw data generated through bioinformatics
Which type of mutation is the most common?
Base substitutions
Which of the following statements about mutations is NOT true?
Mutations occur in all organisms at the same rate.
DNA polymerase never produces mutations during replication because of..
The proofreading ability of this enzyme
Mutations often occur at methylated ___ ___.
Cytosine residues
Mutations such as duplications or deletions occur due to..
Repetitive sequences causing strand slippage
When comparing mutation rates to coding capacity, mutation rates are usually the same for most organisms, which suggests..
A mechanism to control the rate
Which one of the following is often used to establish family trees for organisms because it is present in all organisms and does not accumulate mutations quickly?
rRNA
Which of the following statements about DNA microarrays is NOT correct?
Hybridization to a DNA microarray can only occur once.