Ch. 573 - Hyperparathyroidism

Question 1

Hyperparathyroidism: Caused by excessive production of PTH from defect in the parathyroid gland such an adenoma or hyperplasia

Answer 1

Primary Hyperparathyroidism

Question 2

Hyperparathyroidism: Increased PTH as a compensatory mechanism, usually aimed at correcting hypocalcemic states of diverse origins

Answer 2

Secondary Hyperparathyroidism

Question 3

Childhood hyperparathyroidism is rare and is usually the result of ___ and becomes manifest after ___

Answer 3

A single benign adenoma, 10 y/o

Question 4

Hyperparathyroidism: May occur as part of syndromes

Answer 4

MEN I and Hyperparathyroidism-jaw tumor syndrome

Question 5

Components of MEN I

Answer 5

Neoplasia of the endocrine pancreas, anterior pituitary, and parathyroid glands

Question 6

Parathyroid adenomas + fibro-osseous jaw tumors

Answer 6

Hyperparathyroidism-jaw tumor syndrome

Question 7

T/F Transient neonatal hyperparathyroidism can occur in infants born to mothers with hypoparathyroidism

Answer 7

T

Question 8

Transient neonatal hyperparathyroidism can occur in infants born to mothers with pseudohypoparathyroidism (chronic hypocalcemia)

Answer 8

T, results in hyperplasia of the fetal parathyroid glands

Question 9

Hyperparathyroidism: Serum calcium

Answer 9

Elevated

Question 10

Hyperparathyroidism: Serum phos

Answer 10

Low

Question 11

Hyperparathyroidism: Serum Mg

Answer 11

Low

Question 12

Hyperparathyroidism: Calcitonin

Answer 12

Normal

Question 13

Hyperparathyroidism: Most consistent radiographic finding

Answer 13

Resorption of subperiosteal bone best seen along margins of phalanges of hands

Question 14

Primary Hyperparathyroidism: Serum phos

Answer 14

Low

Question 15

Primary Hyperparathyroidism: Serum Ca

Answer 15

High

Question 16

T/F Surgical exploration is indicated in ALL instances of Hyperparathyroidism

Answer 16

T

Question 17

T/F Most neonates with severe hypercalcemia require total parathyroidectomy

Answer 17

T