Ch. 336 - IBD Flashcards
most common time of onset of IBD is during
the preadolescent/adolescent era and young adulthood
IBD may begin as early as
1st yr of life
UC vs Crohn: pANCA
UC
UC vs Crohn: Smoking is a risk factor
Crohn
UC vs Crohn: Smoking is protective
UC
UC vs Crohn: Rectal bleeding
UC
UC vs Crohn: Diarrhea, mucus, pus
UC
UC vs Crohn: Abdominal pain
Crohn
UC vs Crohn: Abdominal mass
Crohn
UC vs Crohn: Growth failure
Crohn
UC vs Crohn: Perianal disease
Crohn
UC vs Crohn: Rectal involvement
UC
UC vs Crohn: Pyoderma gangrenosum
UC
UC vs Crohn: Erythema nodosum
Crohn
UC vs Crohn: Mouth ulceration
Crohn
UC vs Crohn: Thrombosis
UC
UC vs Crohn: Colonic disease
UC
UC vs Crohn: Ileal disease
Crohn
UC vs Crohn: Backwash ileitis
UC
UC vs Crohn: Stomach-esophageal disease
UC
UC vs Crohn: Chronic gastritis
UC
UC vs Crohn: Strictures, fissures, fistulas
Crohn
UC vs Crohn: Toxic megacolon
UC
UC vs Crohn: Sclerosing cholangitis
UC
UC vs Crohn: Risk for cancer GREATLY increased
UC, increased in both but more with UC
UC vs Crohn: Skip lesions
Crohn
UC vs Crohn: Transmural involvement
Crohn
UC vs Crohn: Crypt abscess
UC
UC vs Crohn: Granulomas
Crohn
UC vs Crohn: Linear ulcerations
UC
UC vs Crohn: Localized to the colon and spares the upper GIT
Idiopathic chronic UC
Fulminant colitis is defined as
Fever, severe anemia, hypoalb, leukocytosis, >5 bloody stools/day for 5 days
Colon cancer is preceded by changes of mucosal dysplasia hence it is recommended that patients with UC >___ should be screened with colonoscopy and biopsies every 1-2 years
10 years
Management for intractable UC and fulminant disease unresponsive to medical management
Colectomy
Major complication of total colectomy for UC
Pouchitis
Used to prevent pouchitis as a complication of total colectomy for UC
Probiotics
UC vs Crohn: Aka regional ileitis/enteritis
Crohn
UC vs Crohn: Systemic signs and symptoms
Crohn
May be the only manifestation of Crohn
Growth failure
UC vs Crohn: Associated with Anti-saccharomyces cervisiae, antibody to E. coli, and anti-flagellin antibodies
Crohn
Most characteristic histologic finding in Crohn disease
Noncaseating granulomas similar to sarcoidosis
UC vs Crohn: Partial small bowel obstruction or thumbprinting of the colon wall on plain abdominal films
Crohn
UC vs Crohn: Cobblestone appearance of ulcerations
Crohn
Trial of this medication may be attempted for mild terminal ileal disease or mild Crohn disease of the colon
Mesalamine
Used for infectious complications and first-line therapy for perianal disease of Crohn
Metronidazole
Mainstay of therapy for acute exacerbation of pediatric Crohn disease
Corticosteroids
Crohn: Treatment of choice for localized disease unresponsive to medical treatment, bowel perforation, fibrosed stricture with partial obstruction, and intractable bleeding
Surgery