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PTA 260 (Pathology) > Ch 3 Tissue Healing: Collagen > Flashcards

Ch 3 Tissue Healing: Collagen Flashcards

1
Q

Predominant structural collagen of the body

A

Type I Collagen

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2
Q

Collagen that constitutes 80-85% of dermal collagen

A

Type I Collagen

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3
Q

Collagen that’s prominent in mature scars, tendon, bone, dentin, joints

A

Type I Collagen

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4
Q

Predominant component of hyaline cartilage (outer ear, end of nose, joint)

A

Type II Collagen

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5
Q

Collagen not present in skin

A

Type II Collagen

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6
Q

Collagen that’s found in nucleus pulposus external annulus

A

Type II Collage

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7
Q

Collagen that is prominent in vascular and visceral structures (blood vessels, GI tract, liver, uterus) but absent in bone and tendon

A

Type III Collagen

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8
Q

Collagen that constitutes 15-20% of dermal collagen

A

Type III Collagen

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9
Q

Collagen that is abundant in embyronic tissues

A

Type III Collagen

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10
Q

The first collagen deposited in wound healing (granulation tissues)

A

Type III Collagen

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11
Q

Collagen found in basement membranes (base of epithelial, endothelial, and mesenchymal cells found in developing fetus), glomeruli of kidney nephron

A

Type IV (4) Collagen

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12
Q

Collagen present in most tissues but never as a major component

A

Type V (5) Collagen

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13
Q

Collagen that’s prominent in fetal membrane, cornea, heart valve, minor component of skin, and synovial membrane

A

Type V (5) Collagen

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14
Q

Prevalent in most connective tissues

A

Type VI (6) Collagen

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15
Q

May be involved in matrix and bone disorders

A

Type VII (7) Collagen

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16
Q

Collagen that anchors filaments of lymphatic vessels

A

Type VII (7) Collagen

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17
Q

Secreted by rapidly proliferating cells

A

Type VIII (8) Collagen

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18
Q

Collage found in basement membranes and may provide a molecular bridge between different types of matrix molecules

A

Type VIII (8) Collagen

19
Q

Minor component of hyaline cartilage; vitreous humor (fluid of eye)

A

Type IX (9) Collagen

20
Q

Formed only in the epiphyseal growth plate cartilage

A

Type X (10) Collagen

21
Q

May have a role in angiogenesis and involved in matrix and bone disorders

A

Type X (10) Collagen

22
Q

Hyaline Cartilage

A

Type XI (11) Collagen

23
Q

Embryonic skin and tendon, periodontal ligament

A

Type XII (12) Collagen

24
Q

Endothelial cells

A

Type XIII (13) Collagen

25
Q

Fetal skin and tendons; similar to type I

A

Type XIV (14) Collagen

26
Q

Provides structural support and tensile strength for almost all tissues and organs of the body

A

Collagen

27
Q

A fibrous protein molecule consisting of three chains of amino acid coiled around one another in a triple helix

A

Collagen

28
Q

What type of stimuli is collagen in extracellular matrix of muscle and tendon sensitive to?

A

Mechanical

29
Q

What type of collagen organization contributes to strength of tendons?

A

Unidirectional or parallel bundles

30
Q

What type of collagen organization contributes to the flexibility of skin and rigidity of bone?

A

In random arrangements

31
Q

What type of collagen organization allows transmission of light in the cornea and vitreous?

A

Right angles

32
Q

What type of collagen organization allows for elasticity of blood vessels?

A

Tubular fashion

33
Q

What type of collagen organization impart tensile strength to collagen fibers and prevent slippage of molecules past one another under tension?

A

Cross-linked (thicker, stronger filamentous structures)

34
Q

Structural stability of the extracellular matrix is primarily a consequence of?

A

Collagen and the extent of cross linking

35
Q

What is the most common form of collagen?

A

Type I Collagen

36
Q

What type of collagen is assembled in a thick bundle that is structurally very strong and found in all body tissues in which it forms bundles together with other collagen types?

A

Type I Collagen

37
Q

What type of collagen is assembled into thin supporting filaments?

A

Type II Collagen

38
Q

What type of collagen has a half-life of about 3 months?

A

Type II Collagen

39
Q

What type of collagen allows maintenance of nutritive exchanges between degenerative external annulus and any healthy remaining tissue, possibly delaying or avoiding further degeneration?

A

Type II Collagen

40
Q

What type of collagen is assembled into thin filaments that make tissues strong but supple and elastic?

A

Type III Collagen

41
Q

What type of collagen is more prevalent in newborns?

A

Type III Collagen

42
Q

What type of collagen enhances wound tensile strength and is the main component of scar tissue that remains after repair is completed?

A

Type I Collagen

43
Q

What type of collagen occurs during the initial stages of tissue repair and secreted by fibroblasts?

A

Type III Collagen

44
Q

What type of collagen is not assembled into fibers and forms the basement membrane to which epithelial, endothelial, and certain mesenchymal cells are anchored?

A

Type IV (4) Collagen

PTA 260 (Pathology) (32 decks)

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