Ch 3 Reversible Cell Injury and Irreversible Cell Injury

Question 1

What produces a stress to the cell’s ability to attain and maintain homeostasis?

Answer 1

Alteration in a cell’s functional environment

Question 2

The extent to which the cell is able to alter mechanisms and regain homeostasis in the altered environment is considered?

Answer 2

An adaptation by the cells or tissues

Question 3

When the cell is unable to adapt, what occurs?

Answer 3

Injury

Question 4

What type of injury occurs if the stress is sufficiently small in magnitude or short enough in duration that the cell is able to recover homeostasis after removal of the stress?

Answer 4

Sublethal or reversible injury

Question 5

When will normal cell structure and function return?

Answer 5

After removal of the stressors or injurious stimulus

Question 6

How do cells react to injurious stimuli?

Answer 6

By changing their steady state to continue to function in a hazardous environment

Question 7

What is caused by the mechanisms of cell injury (Ischemia; infectious agents; immune reactions; genetic, nutritional, physical, and chemical factors)?

Answer 7

Reversible (sublethal) injury

Question 8

What is a sublethal (reversible) injury caused by any of the mechanisms of cell injury?

Answer 8

A transient impairment in the cell’s normal structure or function

Question 9

What type of reversible injury causes an impairment of ion homeostasis within the cells and lead to increased intracellular levels of sodium and calcium?

Answer 9

Acute reversible injury

Question 10

What happens when the cell nucleus remains undamaged and the energy source is restored or the toxic energy is neutralized in an acute reversible injury?

Answer 10

Cell is able to recover and pump ions and excess fluid back out. Swelling will disappear and cell will return to original steady state (reversible cell injury)

Question 11

Plasma membranes that seal off and detach from the cell surface in injured cells

Answer 11

Blebs