CH 3 Tissue Healing

Question 1

Regrowth of original tissue

Answer 1

Regeneration

Question 2

Formation of connective tissue scar

Answer 2

Repair

Question 3

When does tissue healing begin?

Answer 3

Soon after tissue injury/death

Question 4

How does tissue healing occur?

Answer 4

Regeneration or repair

Question 5

The inflammatory cells recruited from blood circulation begin the healing process by?

Answer 5

Breaking down and removing necrotic tissue

Question 6

How does the body break down and remove necrotic tissue?

Answer 6

By phagocytes that secrete degradative enzymes and also phagocytose the cellular debris, connective tissue fragments, and plasma proteins present in dead tissue

Question 7

A complex process influenced by components such as fibronectin, proteoglycans and elastin, collagen, and parenchymal (organ) and endothelial (skin) cells

Answer 7

Healing process

Question 8

One of the earliest proteins to provide structural support that stabilizes the healing tissue

Answer 8

Fibronectin

Question 9

What component of tissue healing has functions that include the formation of scaffold, the provision of tensile strength, and ability to glue other substances and cells together?

Answer 9

Fibronectin

Question 10

Proteins containing carbohydrate chains and sugar

Answer 10

Proteoglycans

Question 11

Secreted in abundance by fibroblasts early during the tissue repair reaction

Answer 11

Proteoglycans

Question 12

Binds to fibronectin and to collagen to help stabilize the tissue undergoing repair

Answer 12

Proteoglycans

Question 13

Can retain water and aid in hydration of the tissue being repaird

Answer 13

Proteoglycans

Question 14

Once the tissue heals, what component contributes to the organization and stability of collagen and creates an electrical charge that gives basement membranes the property of functioning like molecular sieves?

Answer 14

Proteoglycans

Question 15

A protein synthesized and secreted by fibroblasts that becomes cross-linked to form fibrils or long sheets that provide tissues with elasticity

Answer 15

Elastin

Question 16

A molecule that acts as a binding enhancer to facilitate phagocytosis

Answer 16

Opsonin

Question 17

Responsible for attracting fibroblasts and macrophages by chemotaxis to the healing tissue

Answer 17

Fibronectin

Question 18

What tissues have decreased blood supply and healing process requires additional time?

Answer 18

Tendons, ligaments, cartilage, and disk

Question 19

What happens to factors that impede local circulation or deplete the necessary materials?

Answer 19

Delays rehabilitation

Question 20

What are the factors the physiological variables that influence healing?

Answer 20

Age, growth factors, vascular sufficiency

Question 21

What are the general health of individual factors that influence healing?

Answer 21

Immunocompetency, psychological, emotional, and spiritual well-being

Question 22

What are some comorbidities factors that influence healing?

Answer 22

Diabetes, COPD, CHF, cancer, immobility, neurological impairment, alzheimer’s disease, etc

Question 23

What type of factors influence healing?

Answer 23

Physiological variables, general health of individual, presence of comorbidities/diseases, tobacco, alcohol, caffeine, nutrition, local or systemic infection, type of tissue, medical treatment

Question 24

What nutrient is essential for the activity of enzymes that degrade collagen and of enzymes that are responsible ultimately for the induction of protein synthesis?

Answer 24

Zinc

Question 25

What type of nutritional deficiency impairs healing?

Answer 25

Zinc

Question 26

A medical condition or disease that is simultaneously present with another

Answer 26

Comorbidities

Question 27

Proteins produced in cells involved in tissue repair response and regulate a number of cellular reactions involved in healing

Answer 27

Growth factors

Question 28

Regulate cell proliferation, differentiation, and migration; biosynthesis and degradation or proteins; and angiogenesis

Answer 28

Growth factors