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Book - Elston > Ch. 21 - Tumors of fat, muscle, cartilage, and bone > Flashcards

Ch. 21 - Tumors of fat, muscle, cartilage, and bone Flashcards

1
Q

Lipoma, intramuscular lipoma

A

Well-cirumscribed mature lipocytes within a thin capsule.

Intramuscular: Usually of the forehead, displacing muscle fibers

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2
Q

Angiolipoma

A

Clinically tender lipoma with capillary proliferation. Often with erythrocytes and scattered fibrin microthrombi.

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3
Q

Spindle cell lipoma

A

Firm and fixed lipoma with bland CD34+ spindle cells and variable collagen.

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4
Q

Fibrolipoma

A

Well-circumscribed tumor of mature lipocytes containing large bundles of mature collagen

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5
Q

Pleomorphic lipoma

A

Firm tumor of lipocytes containing multinucleate floret giant cells. May have myxoid areas and ropey collagen bundles.

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6
Q

Angiomyolipoma

A

Well-circumscribed tumor with mature fat and smooth muscle radiating in a pinwheel fashion from the walls of muscular vessels.

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7
Q

Hibernoma

A

Grossly brown tumor with multivacuolated mulberry cells.

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8
Q

Nevus lipomatosis superficialis of Hoffmann and Zurhelle

A

Replacement of the dermis with mature fat.

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9
Q

Leiomyoma

A

Long, thin cigar-shaped nuclei with blunt ends. Often with paranuclear glycogen vacuole.

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10
Q

Piloleiomyoma

A

Circumscribed but non-encapsulated nodule of interlaced smooth muscle fibers without mitoses.

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11
Q

Angioleiomyoma

A

Tender subcutaneous nodule with several layers of smooth muscle merging with slit-like vascular spaces.

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12
Q

Leiomyosarcoma

A

Highly cellular, mitotically active and atypical lesion with fusiform cells.

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13
Q

Osteoma cutis

A

Dermal or subcutaneous bone with normal bone features such as haversian canals, osteocytes in lacunae, and osteoclasts.

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14
Q

Relapsing polychondritis

A

Cartilage with surrounding perichondral neutrophils. DIF with continuous IgG/A/M and C3 in the perichondrium.

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15
Q

Accessory tragus (cartilaginous rest)

A

Fibrovascular polyp containing numerous vellus follicles and a core of adipose tissue & cartilage.

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16
Q

Chondroma

A

Circumscribed mass of mature hyaline cartilage with chondrocytes in lacunae. Can calcify

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17
Q

Chordoma

(IHC?)

A

Axial lesion with lobules of physaliphorous cells in a chondroid stroma.

S100+, vimentin+, keratin+

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18
Q

Pseudocyst of the auricle

A

Usually reactive intracartilaginous space without a true lining or inflammatory reaction.

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19
Q

Supernumerary nipple (polythelia)

A

Subtle epidermal thickening with underlying pilosebaceous structures, smooth muscle bundles, adn mammary duct.

20
Q

Mobile encapsulated lipoma (encapsulated fat necrosis, nodular-cystic fat necrosis)

A

Lobules of necrotic fat surrounded by fibrous capsule

21
Q

Smooth muscle hamartoma, becker’s nevus

A

Numerous haphazard bundles of smooth muscle in the dermis.

Becker’s: Hyperpigmented and hypertrichotic

22
Q

Subungual exostosis

A

Bony stalk with fibrocartilaginous cap under the nail plate.

23
Q

Focal dermal hypoplasia (Goltz syndrome)

(cause?)

A

Markedly hypoplastic dermis with adipocytes approaching the papillary dermis

X-linked dominant mutation in PORCN

24
Q
A

Lipoma

25
Q
A

Angiolipoma

26
Q
A

Spindle cell lipoma

27
Q
A

Fibrolipoma

28
Q
A

Pleomorphic lipoma

29
Q
A

Angiomyolipoma

30
Q
A

Hibernoma

31
Q
A

Nevus lipomatosis superficialis

32
Q
A

Piloleiomyoma

33
Q
A

Angioleiomyoma

34
Q
A

Leiomyosarcoma

35
Q
A

Osteoma cutis

36
Q
A

Relapsing polychondritis

37
Q
A

Accessory tragus

38
Q
A

Chondroma

39
Q
A

Chordoma

40
Q
A

Pseudocyst of the auricle

41
Q
A

Supernumerary nipple

42
Q
A

Mobile encapsulated lipoma (localized fat necrosis)

43
Q
A

Smooth muscle hamartoma

44
Q
A

Subungual exostosis

45
Q
A

Goltz syndrome

Book - Elston (30 decks)

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