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Book - Elston > Ch. 18 - Fungal infections > Flashcards

Ch. 18 - Fungal infections Flashcards

1
Q

Tinea

A

Non-pigmented hyphae in stratum corneum, which may be parakeratotic or have inflammatory cells.

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2
Q

Bullous tinea

A

Nonpigmented hyphae in stratum corneum, with massive papillary dermal edema (resembles polymorphous light eruption or Sweet’s syndrome).

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3
Q

Onychomycosis

A

PAS-positive hyphae in subungual debris

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4
Q

Tinea versicolor

A

Loose hyperkeratosis with groups of round spores and short hyphae in stratum corneum (“ziti and meatballs”).

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5
Q

Candidiasis

A

Pseudohyphae in stratum corneum (often vertically oriented) with neutrophils and hyperkeratosis.

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6
Q

Coccidioidomycosis

A

Large uniform spherules with lacy/granular cytoplasm. Refractile wall.

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7
Q

Cryptococcosis

A

Pleomorphic encapsulated yeast. Amount of capsular material inversely proportional to granulomatous infiltrate.

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8
Q

Blastomycosis

A

Pseudoepitheliomatous hyperplasia with intraepidermal pustules. Few organisms within giant cells. Broad-based budding.

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9
Q

Paracoccidioides

A

Small yeast without thick refractile wall. Mariner’s wheel pattern of budding.

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10
Q

Histoplasmosis

A

Small uniform dots within histiocytes, each surrounded by a pseudocapsule. Narrow-based budding.

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11
Q

African histoplasmosis

(organism?)

A

Larger uniform dots with pseudocapsule. Looks like lobomycosis.

Histoplasma duboisii

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12
Q

Lobomycosis (keloidal blastomycosis)

(organism?)

A

Large organisms with pop-bead chain appearance within histiocytes.

Lacazia loboi

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13
Q

Sporotrichosis

A

Stellate abscess with granuloma containing rare cigar-shaped yeasts

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14
Q

Eumycetoma

A

Sinus tracts filled with neutrophils. Central grains made up of fungal hyphae with club-shaped accumulations of immunoglobulins (Splendore-Hoeppli phenomenon)

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15
Q

Acinetomycetoma

A

Sinus tracts filled with neutrophils. Central grains made up of filamentous bacteria with smooth Splendore-Hoeppli phenomenon at periphery.

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16
Q

Tinea nigra

(organism?)

A

Gold to brown hyphae in stratum corneum of acral skin.

Hortaea werneckii

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17
Q

Phaeohyphomycosis

(organism?)

A

Pigmented thick-walled hyphae in tissue with vesicular swelling.

Many black molds (dematiaceous fungi, mildew)

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18
Q

Chromomycosis (chromoblastomycosis)

A

Pseudoepitheliomatous hyperplasia with intraepidermal pustules. Round copper-colored Medlar bodies.

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19
Q

Mucormycosis

A

Broad, hollow, 90-degree branching refractile hyphae with vesel invasion and tissue necrosis.

20
Q

Entomophthoromycosis

A

Indolent infection that resembles zygomycetes.

21
Q

Hyalohyphomycosis

(organism?)

A

Narrow, non-pigmented hyphae in tissue invading vessels causing tissue necrosis.

(any invasive mold excluding zygomycetes)

22
Q

Protothecosis

(organism?)

A

Morulae or eyeball collections of Prototheca.

23
Q

Rhinosporidiosis

(organism?)

A

Huge sporangia with many endospores. Can resemble coccidoides.

Rhinosporidium (but Microcystis aeruginosa is synergistic)

24
Q
A

Tinea

25
Q
A

Bullous tinea

26
Q
A

Onychomycosis (PAS)

27
Q
A

Tinea versicolor

28
Q
A

Candidiasis

29
Q
A

Coccidioidomycosis

30
Q
A

Cryptococcosis

31
Q
A

Blastomycosis

32
Q
A

Paracoccidiomycosis

33
Q
A

Histoplasmosis

34
Q
A

African histoplasmosis

35
Q
A

Lobomycosis

36
Q
A

Sporotrichosis

37
Q
A

Eumycetoma

38
Q
A

Acinetomycetoma

39
Q
A

Tinea nigra

40
Q
A

Phaeohyphomycosis

41
Q
A

Chromomycosis

42
Q
A

Zygomycosis (Rhizopus)

43
Q
A

Hyalohyphomycosis (aspergillosis)

44
Q
A

Protothecosis

45
Q
A

Rhinosporidiosis

Book - Elston (30 decks)

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