Ch 21 Drugs Treating Parkinson And Other Movement Disorders

Question 0

What are 2 other names for Parkinson’s disease

Answer 0

Idiopathic Parkinsonism

Paralysis agitate

Question 1

What is the extrapyramidal system resp 4

Answer 1

Coarse control of voluntary muscles

Composed of basal ganglia cortical areas of the brain

Question 2

How are manifestations of PD described

Answer 2

Degeneration of the neurons that supply dopamine to the striatum occurs resulting in reduced dopamine in the nerve terminals of the nigrostriatal tract

Question 3

What causes PD

Answer 3

Decreased amts of dopamine and increases In the amt of acetylcholine

Question 4

What is the core drug knowledge regarding carbidopa levodopa

Answer 4

Contraindications and precautions: hypersensitivity, undiagnosed pigment lesions
Adverse effects: nausea, vomiting,anorexia, orthostatic hypotension, abnormal movements, cardiac arrhythmias, bruxism, and ballistics
Drug interactions:hydantoins, MAOI, phenothiazines, or TCA

Question 5

How can one maximize therapeutic effects of carbidopa levodopa

Answer 5

Take on an empty stomach

Monitor diet for high protein and pyridoxine