Ch. 18 Adrenergic antagonists

Question 1

Relevant therapeutic applications of Alpha blockade

Answer 1

essential blockade, reversal of toxicity from A1 agonists

Question 2

Adverse effects of A1 blockade

Answer 2

orthostatic hypotension, reflex tachycardia, nasal congestion, inhibition of ejaculation

Question 3

Adverse effects A2 blockade

Answer 3

potentiation of reflex tachycardia

Question 4

Prazosin uses

Answer 4

hypertension, can benefit men with BPH

Question 5

Prazosin adverse effects

Answer 5

orthostatic hypotension, reflex tachycardia, nasal congestion

Question 6

Therapeutic applications of Beta blockade

Answer 6

angina pectoris, hypertension, cardiac dysrhythmias, MI, reduction of perioperative mortality, HF, hyperthyroidism, migraine prophylaxis, stage fright, glaucoma

Question 7

Adverse effects of Beta blockade

Answer 7

bradycardia, reduced cardiac output, precipitation of HF, AV heart block, rebound cardiac excitation

Question 8

Adverse effects of B2 block

Answer 8

bronchoconstriction (do not give to people with asthma), hypoglycemia

Question 9

Propranolol uses

Answer 9

HTN, angina, cardiac dysrhythmias, MI

Question 10

Propranolol adverse effects

Answer 10

bradycardia, AV heart block, HF, rebound cardiac excitation, bronchoconstriction, inhibition of glycogenolysis, CNS effects, effects in neonates

Question 11

Metoprolol uses

Answer 11

HTN is primary use, also can be used for angina, MI, HF

Question 12

Metoprolol adverse effects

Answer 12

bradycardia, reduced cardiac output, AV block, rebound cardiac excitation