Ch. 14 Muscarinic Agonists and Antagonists

Question 1

What drug is representative of muscarinic agonists?

Answer 1

bethanecol (mimics effects of Ach)

Question 2

What drug(s) representative of muscarinic antagonists?

Answer 2

atropine (blocks effects of Ach)

Question 3

Bethanecol uses

Answer 3

urinary retention, investigational GI uses

Question 4

Bethanecol adverse effects

Answer 4

hypotension, bradycardia, excessive salivation, increased secretion of gastric acid, abdominal cramps, diarrhea, increased pressure in urinary tract, exacerbation of asthma, dysrythmias in hyperthyroid patients

Question 5

Antidote for muscarinic poisoning?

Answer 5

atropine

Question 6

Atropine uses

Answer 6

preanesthetic medication, eye exams and ocular surgery, bradycardia, intestinal hypertonicity and hypermotility

Question 7

Atropine adverse effects

Answer 7

dry mouth, blurred vision and photophobia, elevation of intraocular pressure, urinary retention, constipation, absence of sweat, tachycardia, asthma

Question 8

Muscarinic antagonists are also used in the treatment of ___________

Answer 8

overactive bladder

Question 9

Antidote for antimuscarinic poisoning

Answer 9

physostigmine