CH 14 Flashcards
TBI’s (concussion, contusion)
- drowsiness
- lack of focus
- confusion
- amnesia
- headache
Rostral
toward the forehead
Caudal
toward the spinal cord
Cerebrum
83% of brain volume
Cerebellum
50 % of the neurons, 2nd largest region.
Longitudinal fissure
deep groove that separates cerebral hemispheres
Corpus callosum
thick nerve bundle at bottom of longitudinal fissure that connects hemispheres.
Brainstem
-major components
- diencephalon
- midbrain
- pons
- medulla oblongata
Gray matter
the seat of neuron cell bodies, dendrites, and synapses.
- form cortex over cerebrum and cerebellum
- fors nuclei deep within brain.
White matter
bundles of axons
- lies deep to cortical gray matter, opposite than the spinal chord.
- composed of tracts, or bundles of axons, that connect one part of the brain to another, and to the spinal cord.
Meninges
3 connective fissure membranes the envelop the brain.
- dura mater, arachnoid mater, pia mater
- protect the brain and provide structural frame work for it arteries and veins.
Dura mater
2 layers
- periosteal
- meningeal
-cranial dura mater is pressed closely against cranial bones
(no epidural space)
-layers separated by DURAL SINUSES
Arachnoid mater
- subarachnoid space separates it from pia mater below.
- Subdural space separates it from dura mater above in some places.
Pia mater
-very thin membrane that follows contours of brain, even dipping into sulci.
Meningitis
inflammation of the meninges.
- serious disease of infancy and childhood.
- especially between 3 mons and 2 years.
- cause by bacterial and virus invasion of the CNS by way of the nose and throat.
Bacterial meningitis
can cause swelling of the brain, enlargement of the ventricles, and hemorrhage.
- headache, nausea, and stiff neck.
- diagnosed by examining the CSF for bacteria (spinal tap)
lumbar puncture (spinal tap)
draws fluid from subarachnoid space between two lumbar vertebrae.
-L2-L3 or L3-L4
Choroid plexus
spongy mass of blood capillaries.
Ependyma
Neuroglia that lines the ventricles and covers choroid plexus.
-produces CSF
Cerebrospinal fluid
clear, colorless liquid that fills the ventricles and canals of CNS.
-Brain produces and absorbs 500mL/day.
slides 24-28
Functions of CSF
- Buoyancy
- protection (shaken child syndrome and concussions do occur from severe jolting)
- Chemical stability (sleep)
Brain is only___% of the adult body weight, and receives ____% of the blood
2% ; 15%
A 10 second interruption of blood flow may cause ___.
loss of consciousness
A 1 to 2 minute interruption can cause ______.
impairment of neural function.
Going 4 mins without blood cause ______.
irreversible brain damage.
2 points of entry the must be guarded.
- blood capillaries throughout the brain tissue.
- capillaries of the choroid plexus.
Blood-brain barrier
protects blood capillaries through brain tissue.
Astrocytes
reach out and contact capillaries with their perivascular feet.
- induce endothelial cells to form tight junctions that completely seal off gaps between them.
- anything leaving the blood must pass through the cell and not between them.
Endothelial cells
can exclude harmful substances from passing to the brain tissue while allowing necessary ones to pass.
Blood-CSF barrier
protects the brain at the choroid plexus
- blood barrier system is HIGHLY permeable to water, glucose, and lipid soluble substances like oxygen, carbon dioxide, alcohol, caffeine, nicotine, and anesthetics.
- SLIGHTLY permeable to sodium, potassium, chloride, and the waste products urea and creatinine.
circumventricular organs
CVO’s
places in the third and fourth ventricles where the barrier is absent.
- blood has direct access to brain.
- a route for invasion (HIV)
- cocaine and meth damage BBB.
Medulla oblongata
- cardiac center
- vasomotor center
- respiratory center
- reflex center
Pons
communicates with cerebellum.
-sleep and posture
Substantia nigra
produce dopamine
degeneration of neurons leads to tremors of ______ disease.
parkinsons
reticular formation
sleep and consciousness :
-plays a role in states of consciousness such as alertness and sleep.
Habituation (thalamus): process in which the brain learns to ignore repetitive info.
cerebellum
monitors muscle contractions and aids in motor coordination.
- evaluation of sensory input
- timekeeping center
Lessions in the cerebellum may result in ____ and ____.
emotional overreactions and trouble with impulse control.
FAS=ADHD
Diencephalon
- thalamus
- hypothalamus
- epithalamus
Thalamus
- gateway to cerebral cortex
- memory and emotional functions of the limbic system.
Hypothalamus
major control center of autonomic nervous system and endocrine system.
- autonomic effects
- thermoregulation
- food and water intake
- rhythm of sleep and walking
- memory
- emotional behavior