Ch 11 Cell Division Flashcards

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1
Q

What is cell division in Prokaryotes called?

A

Binary Fission

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2
Q

Where do cells spend most of their life

A

Interphase

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3
Q

What are the three phase of Interphase

A

G1- growth
S Phase- DNA replication
G2- Groth

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4
Q

S phase DNA replication turns homologous chromosomes into?

A

Homologous chromosomes with sister chromatids

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5
Q

What are the five phase of Mitosis and what happens during each?

A
  1. Prophase- Chromosomes compact, coil, and become visible, centrosomes make spindles, kite chores are made
  2. Prometaphase- the nuclear envelope breaks down and spindles attach to the kinetochores of the centromeres
  3. metaphase- Chromosomes line up inn the middle of the cell
  4. Anaphase- Spindles retract and pull apart chromosomes drawing then to opposite poles
    5 Telophase/cytokinesis- chromosomes finish moving and uncoil, spindles break down, and nuclear envelope is reformed
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6
Q

To fully split the cells in cytokinesis a ring made of what is needed?

A

Actin ring that pinches them off

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7
Q

What is Meiosis?

A

Production of sexual gametes

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8
Q

Gametes contain how many chromosomes?

A

23 they are haploid until they fuse during reproduction

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9
Q

What is a synapsis?

A

Precise alignment of 2 Homologous chromosomes

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10
Q

How many stages in meiosis?

A

Two stages Meiosis 1 and Meiosis 2

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11
Q

What is the difference between Mitosis and Meiosis?

A

Meiosis has two stages, produces haploid gametes, and In stage 1 homologous chromosomes separate then in meiosis 2 is when the sister schematics separate, in addition meiosis has crossing over that creates variation so none are identical

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12
Q

Haploid Vs Diploid

A

Haploid is gametes that have 23 chromosomes
Diploid is somatic cells who ave 48

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13
Q

What is nondisjunction?

A

Extra or missing chromosomes

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14
Q

What are the three cell cycle checkpoints and where are they?

A

After G1 and it checks for DNA Damage
After G2 and it checks DNA Replication
Before M phase and checks for spindle assembly

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15
Q

What is a CDK?

A

A cyclin dependent kinase

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16
Q

How does a CDK work?

A

When the cyclin binds to the CDK it is the key and phosphorylates target proteins that promote cell division.

17
Q

What happens to P53 that it acts like a tumor suppressor

A

When it becomes phosphorylated it acts as a Transcription Factor that Inhibits the Cell Cycle.

18
Q

What are oncogenes?

A

The mutated form of a proto-oncogene that promotes cancer

19
Q

What is a tumor suppressor?

A

Proteins whose normal job is to inhibit the cell cycle when something goes wrong

20
Q

How do Oncogenes and tumor suppressor work together to promote cancer when mutated?

A

Oncogenes are activated as Tumor Suppressors are Inactivated

21
Q

What is apoptosis?

A

cell programmed death where cells are cut up into blebs and ingested by surrounding cells

22
Q

What is necrosis?

A

When a cell is damaged or starved it Burts causing inflammation