Ch 10 Cell form and function Flashcards
Why are kinases important players in signaling pathways?
They phosphorylate other proteins
Why is phosphorylation important?
they induce a change in protein structure, regulating protein activity by turning it on or off
What are the three components of the cytoskeleton?
Microfilaments, Intermediate filaments, and Microtubules.
What does the cytoskeleton function in?
cell shape, movement, transport, division, and contraction.
Basic info on Microtubules
- Made of tubulin
- Act as tracks for motor proteins
- make cilia and flagella
- maintain shape and structure
- “9+2” array
- are what centrioles are made of
Microfilaments
- Made of Actin
- Cell movement/ shape
- in cytoplasm
- Needed for cell to split
- Act with myosin for transport
Intermediate filaments
1.Made mostly of Keratin
2. coiled into thick cables
3. attach to cell junctions
4. hold skin together
What two components are dynamic
Microtubules and Microfilaments
What are the two types of motor proteins?
dyenin- moves cargo toward negative end
Kinesin- moves cargo towards the plus end
What are cell junctions?
specialized structures in the plasma membrane where cells adhere to other cells and the ECM
What is Caherin adhesion
Cell to cell
What is integrin adhesion
Cell to ECM
Adheren Juction
Connect cells to cells all the way around through cadherins and anchored to actin microfilaments
Desmosomes
Connect cells to cells by cadherins and Intermediate filaments
Tight Junctions
Connect Cells to Cells with no movement of materials. The junctions connect to actin filaments